New Research Study Offers Essential Acumen on Proprotein Convertase Subtilisin - Pipeline Review, H2 2017

Recently, Market Research Hub (MRH) included an in-depth and fact based research publication titled “Proprotein Convertase Subtilisin Pipeline Review, H2 2017” in its extensive research repository. This report publication portrays a comprehensive intelligence on the therapeutics targeted for proprotein convertase subtilisin/ Kexin type 9 (Neutral Apoptosis Regulated Convertase or Proprotein Convertase 9 or EC 3.4.21 or PCSK9) along with complete analysis on stage of development, various indications, route of administration, mechanism of action as well as molecule type.

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The molecules produced by companies in Phase I, Phase II, Phase III, Preclinical, IND/CTA filed, Discovery as well as unknown stages are 4, 3, 1, 8, 3, 6, 1 correspondingly. This research report encompasses all products from the therapeutic areas such as cardiovascular, metabolic disorders, gastrointestinal, infectious diseases, immunology as well as oncology. It also includes indications such as hyperlipidemia, hypercholesterolemia, cardiovascular disease, atherosclerosis, HoFH (Homozygous Familial Hypercholesterolemia), Type 2 diabetes, NASH (Non-Alcoholic Steatohepatitis), hypertriglyceridemia, bacterial sepsis, liver diseases, inflammation, NAFLD (Non-Alcoholic Fatty Liver), metabolic syndrome and PVD (Peripheral Vascular Disease) or PAD (Peripheral Arterial Disease).

Proprotein convertase subtilisin is a PCSK9 gene encoded enzyme in humans. It belongs to the proprotein convertase family which is involved in activation of other proteins in the body. It is universally expressed in several cell types and tissues. It has high medical significance as it participates in homeostasis of lipoproteins. It has a vital role in homeostasis of bad cholesterol, especially reducing the LDLR levels. It is typically synthesized as zymogen which is soluble and in the endoplasmic reticulum it undergoes intermolecular processing that is autocatalytic in nature. It sometimes also has a vital function of differentiating cortical neurons.
Key Competitor Analysis

This research publication also includes analysis on key players dealing with the development of therapeutics associated with PCSK9 along with developments taking into consideration all dormant or active projects in this section. The data is garnered from SEC filings, company websites, proprietary databases, university websites, conferences, registries of clinical trials, press releases as well as investor presentations. Companies like AFFiRiS AG, Betagenon AB, Bioleaders Corp, BioLingus AG, Catabasis Pharmaceuticals Inc., Dicerna Pharmaceuticals Inc., Eli Lilly and Co, Ensemble Therapeutics Corp, Kowa Co Ltd., Novartis AG, Pfizer Inc., Regeneron Pharmaceuticals Inc., Serometrix LLC, Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co Ltd., and The Medicines Company.

Scope of the Report
The report on pipeline analysis for H2 2017 for proprotein convertase subtilisin or PCSK9 covers a global therapeutic scenario of PCSK9 in the second half of 2017. This research report covers weighted analysis on products in pipeline, drug profiles, key players participating in this market along with the completed, on-going or dormant research projects and also reviews upcoming trends, latest news associated with the targeted therapeutics for proprotein convertase subtilisin (PCSK9).

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The Whys to Invest in this Research Report
The report on the pipeline review of proprotein convertase subtilisin offers the much needed value addition considering all angles in this sector. It portrays essential acumen on key competition, strategies, SWOT, and their product developments. It also assists the reader to identify revenue pockets, new clients and partners in targeted regions and also devise and execute vital decisions from a strategic standpoint to gain competitive advantage.

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This release was published on openPR.