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Canavan Disease Therapeutics Patent, Designation, Collaboration, & Other Developments
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Neonatal/infantile Canavan disease is the most common and most severe form of the condition. Affected infants appear normal for the first few months of life. By the age of three to five months, problems with the infant development become noticeable. These infants usually do not develop motor skills such as turning over, controlling head movement, and sitting without support. Other common features of Canavan disease include weak muscle tone (hypotonia), an unusually large head size (macrocephaly), and irritability. Feeding and swallowing difficulties, seizures, and sleep disturbances may also develop.
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The mild/juvenile form of Canavan disease is less common. Affected individuals have mildly delayed development of speech and motor skills starting in childhood. These delays may be so mild and nonspecific that they are never recognized as being caused by Canavan disease. The drug candidates in the pipeline of Canavan disease include, but are not limited to, OPC 1 and ALD 101. Some of the companies having drugs in the Canavan disease pipeline include Turing Pharmaceuticals AG and Pfizer Inc.
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The report provides a comprehensive understanding of the pipeline activities covering all drug candidates under various stages of development, with detailed analysis of pipeline and clinical trials. Pipeline analysis of drugs by phases includes product description and development activities including information about clinical results, designations, collaborations, licencing, grants, technology and others.
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Canavan-van Bogaert-Bertrand or Canavan disease is a rare and fetal genetic condition. It is an autosomal recessive condition that causes damage to cells of nervous system in the brain. It is a common progressive cerebral disease in newborns.
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Canavan disease is caused by the lack of aminoacylase 2 enzyme. Canavan disease is one of the disease condition in leukodystrophies. Leukodystrophies is a set of genetic…
