openPR Logo
Press release

Develop business Strategies Of Myelofibrosis Market 2025

Develop business Strategies Of Myelofibrosis Market 2025

"The Latest Research Report OpportunityAnalyzer: Myelofibrosis - Opportunity Analysis and Forecasts to 2025 provides information on pricing, market analysis, shares, forecast, and company profiles for key industry participants. - MarketResearchReports.biz"

About Myelofibrosis Market

Myelofibrosis (MF) is a rare blood disorder, which is characterized by bone marrow fibrosis. Currently, there is only one approved drug, Incyte/Novartis Jakafi (ruxolitinib), for the treatment of MF, and other conventional therapies used in MF are off-label. However, none of these drugs are curative, and the only potentially curative intervention is allogeneic stem cell transplant (allo-SCT), which is available to a very small percentage of eligible patients because of the high risk of morbidity and mortality. Therefore, there is a huge unmet need for the treatment of MF.

This report highlights the significant unmet need for novel drug treatment for MF, both to alleviate MF-associated complications and to reverse the disease course, across the seven major markets; it also discusses the associated commercial opportunities for new market entrants to gain a foothold in the market. GlobalData anticipate the MF market to almost double, from $545.2m to $1.01 billion, over the forecast period of 2015-2025. The key drivers wills be the launch of pipeline drugs, increasing incidence and an increase in the use of drugs for splenomegaly and constitutional symptoms in the 5EU and Japan.

Highlights

Get Sample Copy Of This Report @ https://www.marketresearchreports.biz/sample/sample/959624

Key Questions Answered

- The MF market has high unmet need. What are the main unmet needs in this market? How will the drugs under development fulfil the unmet needs of the MF market?
- There are three middle- to late-stage MF pipeline drugs expected to launch during the forecast period. Will these drugs make a significant impact on the MF market? Which of these drugs will have the deepest patient penetration and highest peak sales, and why?
- The current MF market is dominated by one JAK inhibitor, Jakafi. How will the launch of pipeline drugs with novel mechanism of action change this? How will the way MF patients are treated change over the next years? What are the key drivers and barriers to this change?

Key Findings

- The launch of premium priced products, in particular second-line treatments for patients who are refractory to Jakafi, will be the main drivers of growth in he MF market.
- There are high unmet needs in MF. The biggest unmet need is for curative treatments. The unmet needs will only be partially addressed by the major pipeline drugs. In addition, there are currently no approved or major pipeline drugs for MF-associated anemia. Any drug that can get approved in this setting can expect a lucrative return.
- Key Opinion Leaders urged pharma companies to focus their R&D strategies on trying to reverse the disease course of MF. This will involve collaborating with academics to identify new molecular targets.
- One key R&D strategy will be developing drugs that reverse bone marrow fibrosis.

View Report @ https://www.marketresearchreports.biz/reports/959624/opportunityanalyzer-myelofibrosis-opportunity-analysis-and-forecasts-to-2025-market-research-reports

Scope

- Overview of MF, including epidemiology, etiology, pathophysiology, symptoms, diagnosis, treatment guidelines and disease management.
- Annualized MF therapeutics market revenue, average cost of therapy and treatment usage pattern data from 2015 and forecast for seven years to 2025.
- Key topics covered include strategic competitor assessment, market characterization, unmet needs, clinical trial mapping and implications for the MF therapeutics market.
- Pipeline analysis: comprehensive data split across different phases, emerging novel trends under development, and detailed analysis of middle- to late-stage pipeline drugs.
- Analysis of the current and future market competition in the global MF therapeutics market. Insightful review of the key industry drivers, restraints and challenges. Each trend is independently researched to provide qualitative analysis of its implications.

Reasons to buy

The report will enable you to -
- Develop and design your in-licensing and out-licensing strategies through a review of pipeline products and technologies, and by identifying the companies with the most robust pipeline. Additionally a list of acquisition targets included in the pipeline product company list.
- Develop business strategies by understanding the trends shaping and driving the global MF therapeutics market.
- Drive revenues by understanding the key trends, innovative products and technologies, market segments, and companies likely to impact the global MF therapeutics market in future.
- Formulate effective sales and marketing strategies by understanding the competitive landscape and by analysing the performance of various competitors.
- Identify emerging players with potentially strong product portfolios and create effective counter-strategies to gain a competitive advantage.
- Track drug sales in the global MF therapeutics market from 2015-2025.
- Organize your sales and marketing efforts by identifying the market categories and segments that present maximum opportunities for consolidations, investments and strategic partnerships.

Send An Enquiry Request @ https://www.marketresearchreports.biz/sample/enquiry/959624

Table of Contents

1 Table of Contents 9
1.1 List of Tables 14
1.2 List of Figures 17
2 Introduction 19
2.1 Catalyst 19
2.2 Related Reports 19
2.3 Upcoming Related Reports 20
3 Disease Overview 21
3.1 Etiology and Pathophysiology 21
3.1.1 Etiology 22
3.1.2 Pathophysiology 23
3.2 Classification and Prognosis 25
3.3 Symptoms 27
3.4 Quality of Life 30
4 Epidemiology 31
4.1 Risk Factors and Comorbidities 32
4.2 Global Trends 34
4.2.1 US 35
4.2.2 5EU 37
4.2.3 Japan 37
4.3 Forecast Methodology 37
4.3.1 Sources Used 37
4.3.2 Forecast Assumptions and Methods 48
4.3.3 Sources Not Used 61
4.4 Epidemiological Forecast of Myelofibrosis (2015-2025) 62
4.4.1 Diagnosed Incident Cases 62
4.4.2 Diagnosed Prevalent Cases 77
4.5 Discussion 90
4.5.1 Epidemiological Forecast Insight 90
4.5.2 Limitations of the Analysis 91
4.5.3 Strengths of the Analysis 92
5 Current Treatment Options 93
5.1 Overview 93
5.2 Diagnosis and Treatment 94
5.2.1 Diagnosis 94
5.2.2 Treatment Guidelines and Leading Prescribed Drugs 99
5.2.3 Clinical Practice 100
5.3 Major Brands - JAK Inhibitors 108
5.3.1 Jakafi (Ruxolitinib) 108
5.4 Conventional Medical Therapy (Off-Label) 120
5.4.1 Cytoreductive Drugs 120
5.4.2 Androgen Therapies 121
5.4.3 Erythropoiesis-Stimulating Agents 124
5.4.4 Immunomodulatory Imide Drugs 124
5.4.5 Anti-fibrotic Agents 126
6 Unmet Needs Assessment and Opportunity Analysis 127
6.1 Overview 127
6.2 Development of Curative Treatments 128
6.2.1 Unmet Need 128
6.2.2 Gap Analysis 129
6.2.3 Opportunity 130
6.3 Treatments for MF Patients with Severe Thrombocytopenia 131
6.3.1 Unmet Need 131
6.3.2 Gap Analysis 131
6.3.3 Opportunity 132
6.4 Second-Line Treatments for MF Patients Refractory to Jakafi 132
6.4.1 Unmet Need 132
6.4.2 Gap Analysis 133
6.4.3 Opportunity 133
6.5 Approved Treatment for MF-Associated Anemia 134
6.5.1 Unmet Need 134
6.5.2 Gap Analysis 134
6.5.3 Opportunity 135
6.6 Effective Treatments with Better Long-Term Safety 135
6.6.1 Unmet Need 135
6.6.2 Gap Analysis 136
6.6.3 Opportunity 137
7 Research and Development Strategies 138
7.1 Overview 138
7.1.1 Targeting the JAK/STAT Signaling Pathway 138
7.1.2 Developing Drugs that Reverse Bone Marrow Fibrosis 139
7.1.3 Second-Line Therapies for Patients After Jakafi Treatment 139
7.1.4 Novel Drugs in Combination with Jakafi 140
7.1.5 Immuno-oncology Approach 141
7.2 Clinical Trial Design 142
7.2.1 Shifting Paradigm of Primary Endpoints Selection 144
7.2.2 Inclusion of MF Patients with Severe Thrombocytopenia 145
7.2.3 Selection of an Appropriate Comparator 146

About us

MarketResearchReports.biz is the most comprehensive collection of market research reports. MarketResearchReports.Biz services are specially designed to save time and money for our clients. We are a one stop solution for all your research needs, our main offerings are syndicated research reports, custom research, subscription access and consulting services. We serve all sizes and types of companies spanning across various industries.

Contact

Mr. Nachiket
State Tower
90 Sate Street, Suite 700
Albany, NY 12207
Tel: +1-518-621-2074
USA: Canada Toll Free: 866-997-4948
Website: http://www.marketresearchreports.biz/
E: sales@marketresearchreports.biz

This release was published on openPR.

Permanent link to this press release:

Copy
Please set a link in the press area of your homepage to this press release on openPR. openPR disclaims liability for any content contained in this release.

You can edit or delete your press release Develop business Strategies Of Myelofibrosis Market 2025 here

News-ID: 642088 • Views: 256

More Releases from MarketResearchReports.biz

Hydro-flyers Market: Moving Towards a Brighter Future
A hydro-flyer is an adventure sporting device which uses the propulsion of water jet technology to create continuous flight movement, where the lift and movement are controlled by the flyer. Hydro-flyers sporting devices make use of the flow of water power to drive the flyer to reach soaring heights. The rise in water sporting facilities is one of the major factors that promote the growth and demand for hydro-flyers in
Outdoor Floodlights: Technology and Market Dynamics
Outdoor floodlights is a reliable, highly efficient, and economical solution for a wide range of outdoor applications. These lights are resistant to temperature fluctuations and they remain stable even in extreme climatic conditions. Unlike the traditional lights, floodlights remain stable and functional even in harsh climatic conditions. This makes them ideal for use in any climate and any outdoor application. Outdoor floodlights save a significant amount of energy and consume
Snow Helmets Market Future Prospects and Regional Outlook
Riders are riding faster and getting bolder day by day. Hence, safety equipment need to be updated as per the requirement and changing time. Earlier, helmets were primarily used by extreme skiers and racers. They were used only on slopes. However, later, the use of helmets was made compulsory. Earlier, bulky black helmets were used by riders, which are outdated at present. Currently, new stylish helmets that can match with
Predictions for 2019: Global Sparkling Water Dispensers Industry Is Set to Boom
Sparkling water dispensers are equipment used for dispensing carbonated water. These dispensers mix the still, filtered water with carbon dioxide before dispensing. Sparkling water dispensers are mostly used in households and commercial establishments such as amusement parks, hotels, restaurants, and sports arenas. A sparkling water dispenser has separate outlets for hot water and cold water. The hot water outlet does not require a separate filtration process. However, cold water is

All 5 Releases


More Releases for Treatment

Medical Tourism Market Report by Treatment Type (Dental Treatment, Cosmetic Trea …
The global medical tourism market accounted for $104.68 billion in 2019, and is projected to reach $273.72 billion by 2027, registering a CAGR of 12.8% from 2019 to 2027 in terms of value. View Full Report: https://reports.valuates.com/market-reports/ALLI-Auto-0P310/medical-tourism In terms of volume, the global medical tourism market accounted for 23,042.90 thousand patients in 2019, and is projected to reach 70,358.61 thousand patients by 2027, registering a CAGR of 15.0% from 2019 to
Stretch Marks Treatment Market by Treatment & Forecast - 2025
Global Stretch Marks Treatment Market: Snapshot In order to expand their outreach and add to their product portfolio, keen players in the global stretch marks treatment market are taking the inorganic route of acquisitions. They are also pouring money into development of new and better products. Rising instances of obesity causing stretch marks is serving to catalyze growth in the market. In addition, growing aesthetic consciousness among people, especially among pregnant women,
Medical Tourism Market by Treatment Type (Dental Treatment, Cosmetic Treatment, …
Medical Tourism Market Overview: The global medical tourism market was valued at $53,768 million in 2017, and is estimated to reach at $143,461 million by 2025, registering a CAGR of 12.9% from 2018 to 2025. Organized travel across international borders to avail medical treatment of some form, which may or may not be available in the travelers home country is defined as medical tourism. Medical tourists travel abroad for the maintenance, enhancement,
Substance Use Disorder Treatment Market By Type (Alcohol abuse treatment, Nicoti …
According to World Health Organization (WHO), the leading cause of disability around the world is not a physical disease, but a serious mood disorder known as depression. Around 350 million people suffer from depression worldwide, and that only about 50% of these individuals will ever receive treatment. According to Anxiety and Depression Association of America, in the U.S., over 15 million adults experience an episode of clinical depression in any
Health Tourism Market Global Industry Analysis, By Key Players, Segmentation, Tr …
Huge increase in demand and new phenomenon in the healthcare industry known as health tourism. It is one of the fastest growing industry and economic growth areas globally, as people today demanding for better quality, faster and cheaper alternatives of healthcare offered in their own countries. Health tourism is also known as medical travel or global health care, defined as the act of travelling to foreign countries with purpose of
Addiction Treatment Market: Tobacco/Nicotine Addiction Treatment Dominates the M …
Transparency Market Research (TMR) has published a new report titled “Addiction Treatment Market – Global Industry Analysis, Size, Share, Growth, Trends, and Forecast, 2017–2025”. According to the report, the global addiction treatment market was valued at approximately US$ 4.0 Bn in 2016 is projected to expand at a CAGR of over 6.0% from 2017 to 2025. The report suggests that growing abuse of prescription drugs and favorable reimbursements for smoking