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Global Cancer Antibody Drug Conjugates Market & Cancer ADC Clinical Pipeline Insight 2022

07-07-2017 08:49 AM CET | Health & Medicine

Press release from: Kuick Resarch

Global Cancer Antibody Drug Conjugates Market & Cancer ADC

Cancer incidences are rapidly escalating across the globe due to which high unmet medical necessities have been felt. Pharmaceutical companies have introduced innovative therapeutics for the cancer treatment which belongs to different drug categories. They have made significant investments in research and development for offering better medical care.

ADCs are new addition to the cancer therapeutic segment which is already overcrowded and consists of numerous competitors. ADCs are based on monoclonal antibodies which delivers chemotherapeutic drugs in highly targeted manner. Their superior pharmacological profiles have allowed the pharmaceutical companies to commercialize them in highly competitive cancer segment.

Monoclonal antibodies have quite strong hold in cancer market due to high therapeutic efficacy along with minimized side effects. But, it was realized that pharmacological profiles of presently available monoclonal antibodies would not be able to offer benefits in future as cancerous cells develop resistance. Moreover, other benefits like remission, quality of life, morbidity, mortality rates and other parameters are modest at their best.

Definitely, monoclonal antibodies are way superior as compared to their traditional counterparts but more improvement is required in order to offer better therapeutic effects. To overcome such issues, concept of ADCs was developed; now this concept has been materialized due to availability of advanced technology.

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Report Table of Contents

Impetus of Antibody Drug Conjugates
1.1 Prologue to Cancer Antibody Drug Conjugate
1.2 The ABCs of ADCs

Structural Entities of Antibody Drug Conjugate
2.1 Rational Design of Antibody Drug Conjugates
2.1.1 Monoclonal Antibody
2.1.2 Linker
2.1.3 Drug Payload
2.2 Aspects of Conjugational Chemistry

Revolutionizing Antibody Drug Conjugates Generation
3.1 First and Second Generation ADCs
3.2 Third Generation ADCs

Mechanism of Cancer Antibody Drug Conjugates
4.1 Sequential Therapeutic Mechanism for Cancer
4.1.1 Selecting an Appropriate Target
4.1.2 Antigen Binding Complex
4.1.3 Antibody Drug Conjugate Internalization
4.2 Approved Antibody Drug Conjugate

Global Cancer Antibody Drug Conjugates Market Overview

Global Cancer Antibody Drug Conjugate Clinical Pipeline Overview
6.1 Phase
6.2 Indication
6.3 Mechanism of Action
6.4 Company
6.5 Formulation

Global Cancer Antibody Drug Conjugates Market Dynamics
7.1 Favorable Market Parameters
7.2 Commercialization Challenges

Global Cancer Antibody Drug Conjugates Market Future Prospects
8.1 Approaching Newer Approaches
8.2 Upcoming Future Market Prospects

Global Cancer Antibody Drug Conjugate Pipeline by Company, Indication and Phase
9.1 Research
9.2 Preclinical
9.3 Clinical
9.4 Phase-I
9.5 Phase-I/II
9.6 Phase-II
9.7 Phase-II/III
9.8 Phase-III
9.9 Preregistration

Marketed Cancer Antibody Drug Conjugate Clinical Insight
10.1 Brentuximab Vedotin (Adcetris)
10.2 Mifamurtide (Junovan and Mepact)
10.3 Gemtuzumab Ozogamicin (Mylotarg)
10.4 Trastuzumab Emtansine (Kadcyla)
10.5 Ibritumomab Tiuxetan (Zevalin and Zevamab)
10.6 Satumomab (OncoScint CR/OV)

Competitive Landscape
11.1 AbbVie
11.2 AbGenomics Corporation
11.3 Biogen Idec
11.4 Biotest
11.5 Bristol-Myers Squibb
11.6 Celldex Therapeutics Inc
11.7 Helix BioPharma
11.8 IBC Pharmaceuticals
11.9 ImmunoGen
11.10 Immunomedics
11.11 Merck
11.12 Millennium
11.13 Nordic Nanovector
11.14 Novartis
11.15 PDL BioPharma
11.16 Progenics Pharmaceuticals
11.17 Roche
11.18 Seattle Genetics
11.19 Stem CentRx
11.20 UCB
11.21 Viventia Biotechnologies

Kuick Research is a market research and analytics company that provides targeted information for critical decisions at business, product and service levels. We are quick, predictive and known by the recommendations we have made in the past. Our result-oriented research methodology offers understanding of multiple issues in a short period of time and gives us the capability to keep you full with loads of practical ideas. By translating research answers into strategic insight and direction, we not only rate the success potential of your products and/or services, but also help you identify the opportunities for growth in new demographies and find ways to beat competition.

Neeraj Chawla
KuicK Research
Avanta Business Center 4th Floor,
Statesman House Barakhamba Road,
Connaught Place New Delhi – 110 001, India

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