Global Cancer Kinase Inhibitors Market Sales Revenue Clinical Trials Pipeline Report

The recent years have witnessed the emergence of kinase inhibitors, which have the potential to offer less toxic and more efficient therapeutic alternatives for patients. Over the past two decades, the researchers have increased their learning about the functioning of these inhibitors, which has led to the achievement of significant milestones of development during this period. The use of inhibitors for treating cancer is gradually increasing. The rising market availability of these agents has enabled the pharmaceutical companies to develop novel combination approaches which have the capability to provide even greater insight into the body’s acceptance of inhibitors so as to develop more efficient drugs.

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"Global Cancer Kinase Inhibitors Market & Pipeline Insight" Table of Contents

1. Introduction to Kinase Inhibitors
1.1 Cancer Growth Blockers
1.2 Types of Cancer Growth Blockers
1.3 Tyrosine Kinase Inhibitors

2. Kinase Inhibitors Classification
2.1 Type I Kinase Inhibitors
2.2 Type II Kinase Inhibitors
2.3 Type III Kinase Inhibitors
2.4 Type IV Kinase Inhibitors or Substrate Directed Inhibitors
2.5 Covalent Inhibitors

3. Mechanisms of Kinase Inhibitors
3.1 Biochemical Mechanism of Action of Tyrosine Kinase
3.2 Oncogenic Activation of Tyrosine Kinase
3.2.1 Activation by Mutation
3.2.2 BCR-ABL and Human Leukemia
3.2.3 TEL-ABL and Human Leukemia
3.2.4 Autocrine-Paracrine Loops
3.2.5 EGFR in Autocrine Paracrine Loops
3.2.6 PDGFR in Autocrine Paracrine Loop
3.2.7 Insulin like Growth Factor Receptors in Autocrine Growth Loop
3.3 Tyrosine Kinases as Targets for Anticancer Agents

4. Need for Cancer Kinase Inhibitor Therapy

5. Cancer Kinase Inhibitors Therapy Market Overview
5.1 Current Market Scenario
5.2 Cancer Kinase Inhibitors Pipeline Overview

6. Cancer Kinase Inhibitors Therapy Market Dynamics
6.1 Favorable Parameters
6.2 Growth Restraints

7. Cancer Kinase Inhibitors Therapy Market Future Outlook

8. Cancer Kinase Inhibitors Therapy Pipeline by Phase, Indication, Company & Country
8.1 Phase: Unknown
8.2 Phase: Research
8.3 Phase: Preclinical
8.4 Phase: Clinical
8.5 Phase-I
8.6 Phase-I/II
8.7 Phase-II
8.8 Phase-II/III
8.9 Phase-III
8.10 Preregistration
8.11 Registered

9. Marketed Cancer Kinase Inhibitors Therapy by Indication, Company & Country

10. Suspended & Discontinued in Cancer Kinase Inhibitors Therapy Pipeline
10.1 No Development Reported
10.2 Discontinued
10.3 Suspended

11. Competitive Landscape
11.1 Amgen
11.2 AstraZeneca
11.3 AVEO Pharmaceuticals
11.4 Bayer HealthCare Pharmaceuticals
11.5 Boehringer Ingelheim
11.6 Deciphera Pharmaceuticals
11.7 Genentech
11.8 GlaxoSmithKline
11.9 Incyte Corporation
11.10 Novartis
11.11 Pfizer
11.12 Takeda

Figure 2-1: Kinase Inhibitors Classification
Figure 3-1: Mechanisms of Constitutive Activation of Kinase Inhibitors
Figure 5-1: Global Market for Kinase Inhibitors (US$ Billion), 2013-2020
Figure 5-2: Global Market for Cancer Kinase Inhibitors (US$ Billion), 2013-2020
Figure 5-3: Regional Break-Up for Kinase Inhibitors Market (%), 2013 & 2020
Figure 5-4: Cancer Kinase Inhibitors Pipeline by Phase (%), 2014
Figure 5-5: Cancer Kinase Inhibitors Pipeline by Phase (%), 2014
Figure 5-6: No Development Reported in Cancer Kinase Inhibitors Pipeline by Phase (%), 2014
Figure 5-7: No Development Reported in Cancer Kinase Inhibitors Pipeline by Phase (Number), 2014
Figure 5-8: Discontinued Cancer Kinase Inhibitors Pipeline by Phase (%), 2014
Figure 5-9: Discontinued Cancer Kinase Inhibitors Pipeline by Phase (Number), 2014
Figure 5-10: Suspended Cancer Kinase Inhibitors Pipeline by Phase (%), 2014
Figure 5-11: Suspended Cancer Kinase Inhibitors Pipeline by Phase (Number), 2014

Table 1-1: Drugs Targeting Kinase Inhibitors
Table 2-1: Comparison Between Different Types of Kinase Inhibitors

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Neeraj Chawla
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