Global Gene Therapy Market Sales Revenue Clinical Trials Pipeline Report

There have been significant advancements in the area of gene therapy in terms of research of new drugs. Over the past 20 years, the gene therapy market has witnessed significant advances ranging from the stage of conception, to the current stage of clinical trials for various disease conditions. When compared to other conventional methods such as radiotherapy and chemotherapy, gene therapy enjoys a clear advantage mainly because this therapy does not inhibit the immune system. Also, there has been an increased use of innovative technologies, which has led to an expansion of the scope of gene therapy worldwide. With continuous growth in this market along with major research and developments breakthroughs, the global market opportunity for gene therapy is expected to reach USD 500 million by 2020.

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"Global Gene Therapy Market & Pipeline Insight" Table of Contents

1. Introduction to Gene Therapy
1.1 History of Gene Therapy
1.2 Vectors of Gene Therapy
1.2.1 Viral Vectors
1.2.2 Non-Viral Vectors
1.3 Gene Therapy Protocol

2. Gene Therapy Classification
2.1 Somatic Gene Therapy
2.1.1 Technique of Somatic Gene Therapy
2.2 Germline Cell Therapy
2.2.1 Technique of Germiline Therapy

3. Mechanism of Gene Therapy
3.1 Approach of Gene Therapy
3.2 Mechanism of Genetic Manipulation

4. Global Gene Therapy Market Overview
4.1 Current Market Scenario
4.2 Gene Therapy Clinical Pipeline Overview
4.3 Emerging Trends in Gene Therapy

5. Significance of Gene Therapy in Cancer Therapeutics

6. Current Applications of Gene Therapy to Cancer Treatment
6.1 Cancer Treatments Currently Available
6.2 Approaches to Cancer Gene Therapy
6.3 Gene Therapy Used in Cancer Treatment
6.4 Methods of Inserting Genes into Cancer Patients
6.5 Cancer Gene Therapy Clinical Insight

7. Global Gene Therapy Market Dynamics
7.1 Favorable Parameters
7.1.1 Curing the Incurable Diseases
7.1.2 Testing Technology
7.1.3 Reimbursement Policy
7.1.4 Rising Incidence of Cancer
7.1.5 Increasing Investments
7.1.6 Integration of Bioinformatics
7.2 Growth Restraints

8. Gene Therapy Market Future Growth Outlook

9. EMA Guidelines for Gene Therapy
9.1 Non Clinical Testing for Inadvertent Germline Transmission of Gene Transfer Vectors
9.2 Scientific Requirements for the Environmental Risk Assessment of Gene Therapy Medicinal Products
9.3 Risk Based Approach Applied to Advanced Therapy Medicinal Products
9.4 Quality, Non Clinical & Clinical Aspects of Medicinal Products Containing Genetically Modified Cells
9.5 Follow Up of Patients Administered with Gene Therapy Medicinal Products
9.6 Non Clinical Studies Required Before First Clinical Use of Gene Therapy Medicinal Products

10. FDA Guidelines for Gene Therapy
10.1 Preclinical Assessment of Investigational Cellular & Gene Therapy Products
10.2 Potency Tests for Cellular & Gene Therapy Products
10.3 Human Somatic Cell Therapy & Gene Therapy
10.4 Gene Therapy Clinical Trials - Observing Subjects for Delayed Adverse Events

11. Gene Therapy Pipeline by Phase, Indications, Country & Company
11.1 Unknown
11.2 Research
11.3 Preclinical
11.4 Clinical
11.5 Phase-I
11.6 Phase-I/II
11.7 Phase-II
11.8 Phase-II/III
11.9 Phase-III
11.10 Preregistration
11.11 Registered

12. Marketed Gene Therapies by Indications, Country & Company
12.1 Gendicine (Shenzhen SiBiono GeneTech)
12.2 Rexin-G (Epeius Biotechnologies)

13. Suspended & Discontinued Gene Therapy in Pipeline
13.1 No Development Reported
13.2 Discontinued
13.3 Suspended

14. Competitive Landscape
14.1 Advantagene
14.2 BioCancell
14.3 Celgene
14.4 Epeius Biotechnologies
14.5 GenVec
14.6 Genethon
14.7 Introgen Therapeutics
14.8 MultiVir
14.9 Shenzhen SiBiono GeneTech
14.10 Vical
14.11 ZIOPHARM Oncology

Figure 1-1: Protocol for Human Gene Therapy Clinical Trials
Figure 2-1: Technique of Somatic Gene Therapy
Figure 2-2: Steps Involved in a Human Germline Gene Therapy Protocol
Figure 3-1: Genetic Modification of Organisms

Figure 4-1: Global Gene Therapy Market Opportunity (US$ Million), 2014-2020
Figure 4-2: Gene Therapy Clinical Pipeline by Phase (%), 2014
Figure 4-3: Gene Therapy Clinical Pipeline by Phase (Number), 2014
Figure 4-4: No Development Reported in Gene Therapy Clinical Pipeline by Phase (%), 2014
Figure 4-5: No Development Reported in Gene Therapy Clinical Pipeline by Phase (Number), 2014
Figure 4-6: Discontinued Gene Therapy Clinical Pipeline by Phase (%), 2014
Figure 4-7: Discontinued Gene Therapy Clinical Pipeline by Phase (Number), 2014
Figure 4-8: Suspended Gene Therapy Clinical Pipeline by Phase (%), 2014
Figure 4-9: Suspended Gene Therapy Clinical Pipeline by Phase (%), 2014

Figure 6-1: Cancer Gene Therapy Drug Clinical Pipeline by Phase (%), 2014
Figure 6-2: Cancer Gene Therapy Drug Clinical Pipeline by Phase (Number), 2014
Figure 6-3: Suspended Cancer Gene Therapy Drug by Phase (%), 2014
Figure 6-4: Suspended Cancer Gene Therapy Drug by Phase (Number), 2014
Figure 6-5: Discontinued Cancer Gene Therapy Drug by Phase (%), 2014
Figure 6-6: Discontinued Cancer Gene Therapy Drug by Phase (Number), 2014
Figure 6-7: No Development Reported Cancer Gene Therapy Drug by Phase (%), 2014
Figure 6-8: No Development Reported Cancer Gene Therapy Drug by Phase (Number), 2014

Figure 14-1: Advantagene Clinical Pipeline
Figure 14-2: Genethon Clinical Pipeline
Figure 14-3: MultiVir Clinical Pipeline
Figure 14-4: Vical Clinical Pipeline
Figure 14-5: ZIOPHARM Oncology Clinical Pipeline

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Neeraj Chawla
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KuicK Research
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