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Global Cancer Immunotoxins Market Sales Revenue Clinical Trials Pipeline Report 2020

06-30-2017 12:19 PM CET | Health & Medicine

Press release from: Kuick Resarch

Global Cancer Immunotoxins Market Sales Revenue Clinical

Immunotoxins are new generation chemotherapeutic agents innovated to include the specificity of monoclonal antibody and cytotoxicity of toxins extracted from plant or bacterial source. The targeting moiety carries the specificity of the antibody and is directed to the target where it either binds to the cell surface antigen, receptor or the ligand of the targeted disease. Cytotoxicity is mediated by the protein toxins, which maybe protein at times.

Download Report:

https://www.kuickresearch.com/report-Global-Cancer-Immunotoxins-Market-&-Clinical-Pipeline-Insight-2020.php

For Report Sample Contact: neeraj@kuickresearch.com or +91-11-47067990

"Cancer Immunotoxins Market & Clinical Pipeline Insight 2020"

Table of Contents

1. Introduction to Immunotoxins

2. Immunotoxins: The Three Generations & Advancements

3. Sources of Toxins
3.1 Plant Toxins
3.2 Bacterial Toxins

4. Production of Immunotoxins

5. Types of Immunotoxins
5.1 Anthrax Based Toxins
5.2 Diphtheria Toxin (DT) & DT Derivatives
5.3 Pseudomonas Exotoxin (PE) & PE Derivatives
5.4 Ribosome Inactivating Proteins Based Immunotoxins
5.4.1 Ricin
5.4.2 Saporin based Immunotoxins
5.4.3 Recombinant Constructs of RIP I Toxins
5.5 Ribonucleases based Immunotoxins
5.6 Proapoptotic Proteins as Targeted Immunotoxins

6. Cancer Immunotoxins Therapy Analysis
6.1 Immunotoxins for Hematologic Malignancies
6.1.1 Denileukin Diftitox (ONTAK, DAB389IL-2)
6.1.2 LMB-2 (anti-Tac[Fv]-PE38)
6.1.3 Moxetumomab Pasudotox
6.1.4 A-dmDT390-bisFv (UCHT1)
6.1.5 DT2219ARL
6.1.6 HuM195-Gelonin
6.2 Immunotoxins for Solid Tumors
6.2.1 SS1P
6.2.2 RG7787
6.2.3 Oportuzumab Monatox
6.2.4 VB6-845
6.2.5 D2C7-(scdsFv)-PE38KDEL

7. Advantages of Immunotoxins upon other Anticancerous Drugs

8. Applications of Immunotoxins
8.1 Immunotoxins against Solid Tumors
8.1.1 Immunotoxin against Colon Carcinoma
8.1.2 Immunotoxin against Breast Cancer & Sarcoma
8.1.3 Immunotoxin against Glioma & Head & Neck Squamous Cell Carcinoma
8.1.4 Immunotoxin against Prostate & Lung Cancer
8.2 Immunotoxins against Leukemias
8.3 Immunotoxin Complementation of HAART to Deplete Persisting HIV-Infected Cell Reservoirs

9. Global Cancer Immunotoxins Market Outlook
9.1 Current Market Scenario
9.2 Cancer Immunotoxins Clinical Pipeline Overview

10. Global Cancer Immunotoxins Market Dynamics
10.1 Favorable Parameters
10.1.1 Large Segment of Patient Still Devoid of Appropriate Medication
10.1.2 Cancer: A Severe Pathological Condition
10.1.3 Unmet Requirement of Completely Curative Agents
10.1.4 Unwanted Effects of the Existing Drugs
10.2 Commercialization Challenges
10.2.1 Stern Regulatory Guidelines: A Major Hurdle
10.2.2 Never Ending Phase of Research & Development
10.2.3 Conduction of Clinical Trials
10.2.4 Funding Research & Development: A Super Costly Affair
10.2.5 Immunogenicity of Immunotoxins

11. Global Cancer Immunotoxins Market Future Prospects

12. Global Cancer Immunotoxins Clinical Pipeline by Company, Indication & Phase
12.1 Research
12.2 Preclinical
12.3 Phase-I
12.4 Phase-I/II
12.5 Phase-II
12.6 Phase-II/III
12.7 Phase-III

13. Discontinued & No Development in Cancer Immunotoxins Clinical Pipeline by Company, Indication & Phase
13.1 No Development Reported
13.2 Discontinued
13.3 Suspended

14. Competitive Landscape
14.1 AbbVie
14.2 AbGenomics
14.3 Agensys
14.4 Ambrx
14.5 Amgen
14.6 AREVA Med
14.7 Bayer HealthCare
14.8 Biotest
14.9 Celldex Therapeutics
14.10 CuraGen Corporation
14.11 Genentech
14.12 Genmab
14.13 Heidelberg Pharma
14.14 ImmunoGen
14.15 Neurocrine Biosciences
14.16 Research Corporation Technologies
14.17 Sanofi
14.18 Seattle Genetics
14.19 Sorrento Therapeutics
14.20 Spirogen

Figure 2-1: Immunotoxins & Their Recombinant Forms
Figure 3-1: Sources of Toxins
Figure 4-1: Steps Involved in Production of Immunotoxins
Figure 5-1: Different Types of Immunotoxins
Figure 5-2: Mechanism of Action of Anthrax Based Immunotoxins
Figure 5-3: Composition of the Diphtheria Derived Toxins
Figure 5-4: Steps Involved in Apoptosis by Diphtheria Derived Immunotoxins
Figure 5-5: Domains of PE with Their Specificities
Figure 5-6: Mode of Apoptosis Taken by Pseudomonas Exotoxin (PE) & PE Derivatives
Figure 6-1: Major Targets of Immunotoxins as Anticancer Agents
Figure 6-2: Some of Important Immunotoxins Targeting Hematological Malignancies
Figure 6-3: Some of Important Immunotoxins Targeting Solid Tumors
Figure 8-1: Major Applications of Immunotoxins
Figure 9-1: Cancer Immunotoxins Pipeline by Phase (%), 2016
Figure 9-2: Cancer Immunotoxins Pipeline by Phase (Numbers), 2016
Figure 9-3: Cancer Immunotoxins Pipeline by Phase (%), 2016
Figure 9-4: Cancer Immunotoxins Pipeline by Phase (Numbers), 2016
Figure 10-1: Favorable Parameters for Global Cancer Immunotoxins Market
Figure 10-2: Commercialization Challenges for Global Cancer Immunotoxins Market
Figure 14-1: AbGenomics - Clinical Pipeline
Figure 14-2: Amgen - Clinical Pipeline
Figure 14-3: Biotest – Clinical Pipeline
Figure 14-4: Genmab - Clinical Pipeline
Figure 14-50: Genmab - Clinical Pipeline
Figure 14-6: Neurocrine Biosciences – Clinical Pipeline
Figure 14-7: Sorrento Therapeutics – Clinical Pipeline

Table 5-1: Immunotoxins in Clinical Development using Diphtheria as a Toxin Moiety
Table 5-2: Clinically evaluated/under evaluation PE-based Immunotoxins against Hematologic Malignancies
Table 5-3: Clinically evaluated/under evaluation PE-based Immunotoxins against Solid Tumors
Table 5-4: Clinical Trials in Patients with Saporin Containing Immunotoxins
Table 6-1: Immunotoxins for Leukemia

Kuick Research is a market research and analytics company that provides targeted information for critical decisions at business, product and service levels. We are quick, predictive and known by the recommendations we have made in the past. Our result-oriented research methodology offers understanding of multiple issues in a short period of time and gives us the capability to keep you full with loads of practical ideas. By translating research answers into strategic insight and direction, we not only rate the success potential of your products and/or services, but also help you identify the opportunities for growth in new demographies and find ways to beat competition.

Neeraj Chawla
neeraj@kuickresearch.com
KuicK Research
Avanta Business Center 4th Floor,
Statesman House Barakhamba Road,
Connaught Place New Delhi – 110 001, India
+91-11-47067990

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