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Chronic Heart Failure Therapeutics Pipeline Analysis, 2017 - Clinical Trials & Results, Collaboration, and Other Developments
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Chronic heart failure is a condition, in which heart muscles gets damaged and cannot pump blood properly. This condition slows down the rate of blood flow and increases the pressure, resulting in insufficient supply of oxygen and nutrients to the body. The damage can be a result of heart attack or long-term health issues like diabetes, high blood pressure and heart disease. Heart failure can be caused by several conditions including heart attack, coronary artery disease, thyroid, kidney disease and cardiomyopathy. Some of the symptoms of chronic heart failure include lung congestion, dizziness, fluid and water retention, fatigue, irregular heartbeats and weakness. Chronic heart failure is categorized into two types, systolic dysfunction and diastolic dysfunction. Heart failure is diagnosed by analysing patient’s medical history and examining the symptoms. Also, alcohol consumption, smoking and drugs intake are considered while diagnosing the disease. Certain tests are also conducted for confirmation which includes blood tests, chest X-ray, B-type natriuretic peptide blood test, electrocardiogram, echocardiogram, cardiac catheterization and the ejection fraction test. Chronic heart failure can be treated with strict medications and healthy lifestyle with regular monitoring. The treatment initially aims to decrease the symptoms and improve the quality of life of the patient.
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Some of the companies having a pipeline of chronic heart failure therapeutics include Amgen, Inc., Bayer AG, Boehringer Ingelheim GmbH, GlaxoSmithKline plc, Daiichi Sankyo Company Ltd., F. Hoffmann-La Roche Ltd., Merck & Co. Inc., Novartis AG, Sulfagenix Australia Pty Ltd., Janssen Research & Development, LLC, AstraZeneca plc, Bristol-Myers Squibb Company, MorphoSys AG.
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