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Glioma Therapeutics Pipeline Analysis, 2017 - Designation, Collaboration, and Other Developments
The pipeline for glioma therapeutics is expected to experience rising research activities in future due to raise in funding by the orphan disease organization such as, National Organization of Rare Disorders. Many novel therapies such as, gene therapies, cell therapies are being developed for the treatment of glioma. Various technological advancements in research and development techniques is also be one of the key factors leading to the upsurge in the growth of glioma pipeline therapeutics. Additionally, increasing awareness among people regarding various health issues and treatments available is also adding to the development of glioma therapeutic pipeline.Explore Report at: www.psmarketresearch.com/market-analysis/glioma-therapeutics-pipeline-analysis
Glioma is a type of brain tumour that arise from glial cells, which provide a protective aid to the neuron in brain. There are basically three types of tumours in which glial cells are involved such as, astrocytoma, ependymomas and oligodendromas. Some of the most common symptoms that occur in glioma are, nausea, headache, confusion, memory loss, seizure, one-sided weakness, difficulty in walking and personality changes. Patients already suffering from brain tumour are usually at a high risk of also developing other diseases such as deep vein thrombosis, pulmonary embolism or brain stroke. Glioma in brain can be diagnosed with the help of MRI scanning. The treatments of glioma include, surgery, chemotherapy, brachytherapy, radiation therapy and treatments with steroids.
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In October 2015, Merck & Co., Inc. and DNAtrix entered into a collaboration for the purpose of developing as well as monitoring the safety and efficacy of the drug DNX-2401, which mostly target the retinoblastoma (Rb) pathway. DNX-2401 has shown strong killing potential against recurrent glioblastoma by inhibiting Retinoblastoma (Rb) pathway, which is usually present in many cancers. In January 2015, Bristol-Myers Squibb and Eli Lilly and Co. entered into a collaboration to evaluate nivolumab in combination with galunisertib in advance solid tumours. Opdivo is a programmed cell death blocker and galunisertib selectively blocks TGF beta signalling pathway, which led to suppression of tumour cell growth.
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Some of the companies having a pipeline of glioma therapeutics include, Teva Pharmaceutical Industries, Ltd., Sun Pharmaceutical Industries, Ltd., Arbor Pharmaceuticals LLC., and F. Hoffmann-Le Roche AG, Agios Pharmaceuticals, Inc., Merck & Co., Inc., Daiichi Sankyo Co., Ltd., Angiochem Inc., Eurofarma Laboratorios S.A., Genentech, Inc.
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