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Candidiasis Therapeutics Pipeline Analysis, 2017 - Clinical Trials & Results, Collaboration, and Other Developments

05-18-2017 01:10 AM CET | Health & Medicine

Press release from: P&S Market Research - Pharmaceuticals

Candidiasis Therapeutics Pipeline Analysis, 2017 - Clinical

Candidiasis therapeutic pipeline is expected to witness increase in coming years due to rising prevalence of the disease resulting from use of corticosteroid medications, pregnancy, long-term use of broad-spectrum antibiotics and increasing health awareness. According to the data by Centers for Disease Control and Prevention, around 46,000 new cases of candidiasis occur every year in the U.S. Also, nearly 75% of all adult women have had at least one "yeast infection" in their lifetime. Candidiasis has become common healthcare-associated infection globally. The incidence and the distribution of candida species causing infection vary significantly by geographic location and patient population. Candida infections are often associated with high rates of mortality and morbidity as well as increases in hospital cost for patients and duration of hospital stay. It affects mainly females and occurs very rarely in males.

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Candidiasis is a type of common fungal infection caused by fungus known as candida. Candida lives in various parts of our body including mouth, skin or belly and cause no harm. But when it gets right environment it multiplies and grows uncontrollably, resulting in the occurrence of the infection, known as candidiasis. There are many different types of candidiasis like thrush (oropharyngeal candidiasis), genital yeast infection (genital candidiasis), diaper rash from yeast infection and invasive candidiasis. The symptoms of candidiasis include disfiguring lesions, nausea, vomiting, abdominal pain, sore and painful mouth, whitish patches on the oral mucosa, dysphagia, retrosternal pain, fever and chills. The diagnosis of candidiasis is based on the type of candidiasis. Mucocutaneous candidiasis is diagnosed by wet mount, microscope examination and gram stain, cutaneous candidiasis is diagnosed by wet mount, microscope examination and potassium hydroxide smears. Genitourinary candidiasis is diagnosed by urinalysis and urine fungal cultures while gastrointestinal candidiasis is diagnosed by endoscopy. The treatment of candidiasis includes the use of topical antifungal agents or fluconazole.

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Some of the companies having a pipeline of candidiasis therapeutics include Matinas BioPharma Nanotechnologies, Inc., Pfizer, Medinova AG, Merck Sharp & Dohme Corp., ProFem GmbH, Scynexis, Inc., Cidara Therapeutics Inc., Viamet Pharmaceuticals, Inc., NovaDigm Therapeutics, Inc., TGV-Laboratories.

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