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Kaposi sarcoma Therapeutics Pipeline Analysis, 2017 - Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments
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According to American Cancer Society, Kaposi sarcoma (KS) is a cancer that develops from the cells that line lymph or blood vessels. It usually appears as tumors on the skin or on mucosal surfaces such as inside the mouth, but tumors can also develop in the other parts of the body, such as in the lymph nodes (bean-sized collections of immune cells throughout the body), the lungs, or digestive tract. The abnormal cells of kaposi sarcoma form purple, red, or brown blotches or tumors on the skin. These affected areas are called lesions. The skin lesions of Kaposi sarcoma most often appear on the legs or face. They may look bad, but they usually cause no symptoms. At times, some lesions on the legs or in the groin area may cause the legs and feet to swell painfully.
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Many companies have a pipeline of drugs for the treatment of Kaposi sarcoma, which are under clinical development. Vasgene Therapeutics, Inc plans to introduce a recombinant EphB4-HSA fusion protein, which is currently in Phase II. Recombinant EphB4-HSA fusion protein showed a promising result in blocking growth of blood vessels that provide blood to cancer. Apogee Biotechnology Corporation also plans to introduce a drug ABC294640, which is currently in Phase I clinical development for treatment of Kaposi sarcoma. Chiltern International Inc. plans to introduce a biological, XmAb13676, which is currently in Phase I clinical development. XmAb13676 is a monoclonal antibody expected to target CD20 expressing malignancies.
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Some of the companies having a pipeline of kaposi sarcoma therapeutics include Bristol-Myers Squibb, Eli Lilly and Co., F. Hoffman-La Roche, AG, GlaxoSmithKline plc, Johnson & Johnson, Pfizer, Inc., and Merck & Co., Inc.
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