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Fallopian Tube Cancer Therapeutics Pipeline Analysis, 2017 by P&S Market Research
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The fallopian tube is a part of female reproductive system and are a pair of thin tubes that transport ova from women’s ovaries to the uterus where they are either fertilized by male sperm or discarded during menstruation. In fallopian tube cancer, an abnormal growth of malignant cells occurs in one or both of a woman's fallopian tubes. The most common fallopian tube cancers are papillary serous adenocarcinomas. The papillary serous adenocarcinomas are an abnormal growth of the fallopian tube cells. Fallopian tube cancer mainly affects women from ages 18-88, and is most commonly found in women aged between 40 and 65 years old.
The pipeline of fallopian tube cancer therapeutics includes, but is not limited to atezolizumab (MPDL 3280A), Ribociclib and Binimetinib. Atezolizumab is being developed by F. Hoffmann-La Roche AG. It is a monoclonal antibody targeting programmed cell death-1 ligand 1 (PD-L1 or CD274 antigen). PD-L1 plays an important role in suppressing the immune system triggered by disease.
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According to the National Cancer Institute, a part of National Institute of Health (NIH), in the year 2016, an estimated 22,280 women in the U.S. are expected be diagnosed with ovarian cancer, and the vast majority of these are high-grade serous ovarian cancers which begins in a fallopian tube. Around 14,240 deaths from the fallopian tube occurred in the year 2016.
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Some of the companies having a pipeline of fallopian tube cancer therapeutics include Amgen Inc., AstraZeneca plc, Bayer AG, Boehringer Ingelheim GmbH,
Bristol-Myers Squibb, Celgene Corporation, Eli Lilly and Company, GlaxoSmithKline plc, Incyte Corporation and F. Hoffmann-La Roche AG.
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