Opioids Market - Global Industry Analysis 2024
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Opioids are a class of drugs that include potential pain relievers prescribed legally and also includes the illegal drug heroin. Pain relieving drugs are chemically related with opioid receptors on nerve cells in the body. Use of prescribed opioid drug for a short period of time is safe for pain management. However, these drugs are frequently misused by taking the dose through a different route and in a greater quantity than the quantity actually prescribed, as they provide a sense of euphoria along with relieving pain. Such is the nature of opioid drugs that drug dependence can occur despite use as prescribed over prolonged use. Overdose of opioid pain relievers can be fatal. Furthermore, according to National Institute of Drug Abuse, there has been significant increase in deaths related to drug overdose, which involved the prescription opioid pain relievers and various federal and state laws have been applied to curb this epidemic. In 2011, the White House released an interagency strategy that focuses on federal agencies working in close coordination with states, education providers, parents, youth, patients and pharmacists. The main objective of the strategy is to increase awareness among the populace and across the value chain about consequences of prescription drug abuse and the requirement of appropriate prescribing, disposal and dispensing for effective prescription drug monitoring programs and also to enable exact medication disposal through prescription take-back initiatives.
Aggressive government strategies have led to fruition, with a noticeable decrease in prescription opioid drugs availability and lower number of case of deaths caused by overdose across various regions. While a large number of applications for opioids and its derivatives exist in the healthcare sector, research currently underway are expected to lead to several more novel applications of opioids. This in turn is projected to favor growth of the opioid market over the forecast period. Furthermore, chronic pain is a widespread problem and a major reason for rise significant potential for legally prescribed opioids such as morphine and codeine. According to British Journal of Anesthesia, in 2013, around 20% of the population in Europe suffered from chronic pain, leading to an estimated economic burden of over US$ 250 billion in Europe and around $150 billion per annum in the U.S.
The pain relieving segment is projected to gain significant traction over the forecast period, owing to the various new product launches and extensive R&D activities leading to major product advancements, which is further due to significant number of collaborations and acquisitions taking place in the opioids market. In 2015, Depomed, Inc.—a specialty pharmaceuticals company focused on products to treat pain and other neurological conditions—officially entered into a definitive agreement to acquire NUCYNTA—a Janssen Pharmaceuticals, Inc. franchise, in order to strengthen the pain management segment of the company. Furthermore, in 2016, China-based drug maker Humanwell Healthcare Group and PuraCap Pharmaceutical LLC.—a generic drug maker—entered into a definitive agreement to acquire 100% assets of Epic Pharma for US$ 550 Mn. This is expected to strengthen the company’s product portfolio by inclusion of drugs such as naltrexone and oxycodone hydrochloride.
Key takeaways of the market:
The global opioids market is expected to expand at a CAGR of 4.2% during the forecast period (2016–2024). Rising prevalence of chronic pain worldwide is expected to favor growth of the market for opioids over the forecast period.
The codeine segment in the global opioids market was estimated to be the largest in 2015 and is expected to dominate the market throughout the forecast period in terms of value.
By therapeutic application, opioids are expected to witness majority of the demand from pain management. The segment accounted for 79.6% of overall market revenue in 2015. Much of the demand generates from neuropathic pain.
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The global opioids market is characterized by strategic research and development and advancements in the technology of vaccines production. Also, the rise in adoption for poultry business globally is expected to favor the market for opioids market.
Some of the major players are Pfizer Inc., Purdue Pharma, Boehringer Ingelheim, Janssen Pharmaceuticals, Inc., Actavis Plc., Sanofi, Sun Pharmaceutical Industries Ltd., Mallinckrodt Pharmaceuticals, Egalet Corporation, and Endo Pharmaceuticals Inc.
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