Chronic Myeloid Leukemia Clinical Trial Pipeline Appears Robust With 20+ Key Pharma Companies Actively Working in the Domain | DelveInsight

DelveInsight's, "Chronic Myeloid Leukaemia Pipeline Insight, 2026" report provides comprehensive insights about 20+ companies and 20+ pipeline drugs in Chronic Myeloid Leukaemia pipeline landscape. It covers the Chronic Myeloid Leukemia pipeline drug profiles, including clinical and nonclinical stage products. It also covers the Chronic Myeloid Leukemia pipeline therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

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Key Takeaways from the Chronic Myeloid Leukemia Pipeline Report

* On January 08, 2026- M.D. Anderson Cancer Center initiated a phase II trial studies the effect of ASTX727 and dasatinib in treating patients with newly diagnosed Philadelphia chromosome or BCR-ABL positive chronic myeloid leukemia in chronic phase. Philadelphia chromosome positive and BCR-ABL positive are types of genetic mutations (changes). Chemotherapy drugs, such as ASTX727, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Dasatinib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. ASTX727 and dasatinib may help to control Philadelphia chromosome-positive chronic myeloid leukemia or BCR-ABL positive chronic myeloid leukemia in chronic phase.
* On January 06, 2026- Novartis Pharmaceuticals announced a study is constituted of two stage: Treatment-Free Remission 1 (TFR1) stage and Treatment-Free Remission 2 (TFR2) stage. The purpose of the TFR1 stage is to assess the effect of nilotinib reduced to half the standard dose for 12 months on treatment-free remission in patients with Chronic Myeloid Leukemia - Chronic Phase (CML-CP) treated with first-line nilotinib who reached a sustained deep molecular response before entering the study.
* DelveInsight's Chronic Myeloid Leukemia pipeline report depicts a robust space with 20+ active players working to develop 20+ pipeline therapies for Chronic Myeloid Leukemia treatment.
* The leading Chronic Myeloid Leukemia Companies such as Kartos Therapeutics, AOP Orphan Pharmaceuticals, Biokine Therapeutics, Incyte Corporation, Sana Biotechnology, Novartis, Nerviano Medical Sciences, Sun Pharma Advanced Research Company and others.
* Promising Chronic Myeloid Leukemia Pipeline Therapies such as Imatinib mesyl, Dasatinib, Nilotinib, decitabine (5-aza-2'deoxycytidine), Asciminib, Bosutinib, Peginterferon alfa-2a , and others.

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Chronic Myeloid Leukemia Overview

Chronic Myeloid Leukemia is a type of blood cancer that starts in the bone marrow, where blood cells are made. It occurs when a genetic change leads to the uncontrolled growth of myeloid cells-the cells that normally develop into red blood cells, platelets, and certain white blood cells. CML is most often caused by a specific genetic abnormality called the Philadelphia chromosome, which forms when two chromosomes (9 and 22) swap pieces. This creates the BCR-ABL1 gene, which produces an abnormal protein that sends constant signals telling blood cells to grow and divide uncontrollably.

Chronic Myeloid Leukemia Emerging Drugs Profile

* Navtemadlin : Kartos Therapeutics

Navtemadlin (KRT-232) is a novel, potent, and selective oral MDM2 inhibitor. Currently, the drug is undergoing an Open-Label, Multicenter, Phase 1b/2 Study of the Safety and Efficacy of KRT-232 Combined with a Tyrosine Kinase Inhibitor (TKI) in Patients with Relapsed or Refractory Ph+ Chronic Myeloid Leukemia (CML).

* Ropeginterferon alfa 2b : AOP Orphan Pharmaceuticals

Ropeginterferon alfa-2b was discovered by PharmaEssentia Corp. based in Taiwan. BESREMi (Ropeginterferon alfa-2b) is a novel, long-acting, mono-pegylated proline interferon .Its pharmacokinetic properties offer a new level of tolerability.

The Chronic Myeloid Leukemia Pipeline Report Provides Insights into

* The report provides detailed insights about companies that are developing therapies for the treatment of Chronic Myeloid Leukemia with aggregate therapies developed by each company for the same.
* It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Chronic Myeloid Leukemia Treatment.
* Chronic Myeloid Leukemia Companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
* Chronic Myeloid Leukemia Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.
* Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the Chronic Myeloid Leukemia market

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Chronic Myeloid Leukemia Companies

Kartos Therapeutics, AOP Orphan Pharmaceuticals, Biokine Therapeutics, Incyte Corporation, Sana Biotechnology, Novartis, Nerviano Medical Sciences, Sun Pharma Advanced Research Company and others.

Chronic Myeloid Leukaemia pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as

* Intra-articular
* Intraocular
* Intrathecal
* Intravenous
* Ophthalmic
* Oral
* Parenteral
* Subcutaneous
* Topical
* Transdermal
* Molecule Type

Chronic Myeloid Leukemia Products have been categorized under various Molecule types such as

* Oligonucleotide
* Peptide
* Small molecule
* Product Type

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Scope of the Chronic Myeloid Leukemia Pipeline Report

* Coverage- Global
* Chronic Myeloid Leukemia Companies- Kartos Therapeutics, AOP Orphan Pharmaceuticals, Biokine Therapeutics, Incyte Corporation, Sana Biotechnology, Novartis, Nerviano Medical Sciences, Sun Pharma Advanced Research Company and others.
* Chronic Myeloid Leukemia Pipeline Therapies- Imatinib mesyl, Dasatinib, Nilotinib, decitabine (5-aza-2'deoxycytidine), Asciminib, Bosutinib, Peginterferon alfa-2a, and others.
* Chronic Myeloid Leukemia Therapeutic Assessment by Product Type: Mono, Combination, Mono/Combination
* Chronic Myeloid Leukemia Therapeutic Assessment by Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III

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Table of Contents

* Introduction
* Executive Summary
* Chronic Myeloid Leukaemia: Overview
* Pipeline Therapeutics
* Therapeutic Assessment
* Chronic Myeloid Leukaemia- DelveInsight's Analytical Perspective
* Late Stage Products (Phase III)
* Drug Name : Company Name
* Mid Stage Products (Phase I/ II)
* Navtemadlin: Kartos Therapeutics
* Early Stage Products (Phase I)
* Drug Name: Company Name
* Preclinical and Discovery Stage Products
* Drug Name: Company Name
* Inactive Products
* Chronic Myeloid Leukaemia Key Companies
* Chronic Myeloid Leukaemia Key Products
* Chronic Myeloid Leukaemia- Unmet Needs
* Chronic Myeloid Leukaemia- Market Drivers and Barriers
* Chronic Myeloid Leukaemia- Future Perspectives and Conclusion
* Chronic Myeloid Leukaemia Analyst Views
* Chronic Myeloid Leukaemia Key Companies

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