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Acute Coronary Syndrome Market Set for Steady Growth to USD 14.70 Billion by 2031, Led by North America's 42% Market Share | DataM Intelligence

01-09-2026 08:38 AM CET | Health & Medicine

Press release from: DataM intelligence 4 Market Research LLP

Acute Coronary Syndrome Market

Acute Coronary Syndrome Market

The Global Acute Coronary Syndrome Market reached USD 9.94 billion in 2023 and is expected to reach USD 14.70 billion by 2031, growing at a CAGR of 5.1% during the forecast period 2024-2031.

Market growth is driven by the rising prevalence of cardiovascular diseases, increasing incidence of acute myocardial infarction and unstable angina, and growing adoption of antiplatelet and anticoagulant therapies. Advancements in percutaneous coronary interventions (PCI), expanding use of novel oral anticoagulants, rising investments in cardiovascular R&D, and increased regulatory approvals for next-generation stents and imaging diagnostics are further accelerating market expansion.

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United States: Key Industry Developments
✅ November 2025: Janssen Research & Development advanced its Phase III PCSK9 inhibitor for Acute Coronary Syndrome (ACS), showing improved lipid-lowering efficacy in post-ACS patients, targeting residual cardiovascular risk reduction.​

✅ September 2025: The Asia Pacific ACS market projected growth to USD 2.64 billion, driven by China's investments in cardiovascular research and Japan's precision medicine initiatives for ACS treatment.​

✅ August 2025: Over five active ACS pipeline assets, including Factor XIa inhibitors from Hyloris Pharmaceuticals, focusing on antithrombotic therapies to prevent recurrent events.​

Asia Pacific / Japan: Key Industry Developments
✅ November 2025: Japan advanced precision medicine for ACS via extensive healthcare infrastructure, emphasizing personalized treatment protocols amid rising cardiovascular cases.​

✅ October 2025: China allocated substantial funding for ACS patient outreach and research programs, boosting early intervention as part of national health strategies.​

✅ September 2025: Asia Pacific cath-lab infrastructure expanded rapidly in urban areas, with telecardiology support enhancing ACS emergency care access in emerging markets like India.

Key Mergers and Acquisitions:
✅ Bristol Myers Squibb enhanced its cardiovascular portfolio through the acquisition of Kiniksa Pharmaceuticals, advancing therapies for inflammatory conditions linked to Acute Coronary Syndrome.​

✅ AstraZeneca partnered with Ionis Pharmaceuticals to develop eplontersen, targeting proteins involved in ACS-related cardiovascular events.​

✅ Leading ACS market players pursued strategic mergers to broaden treatment portfolios and reinforce dominance in acute cardiovascular care segments.​​

Market Segmentation Analysis:
-By Type: NSTEMI Leads with Highest Incidence
Non-ST-elevation myocardial infarction (NSTEMI) holds the largest share at 50%, common in partial blockages causing ongoing chest pain without full infarction.
ST-elevation myocardial infarction (STEMI) captures 35%, marked by complete artery blockage needing urgent reperfusion.
Unstable angina accounts for 15%, involving reduced blood flow without heart damage, often a precursor to infarction.

-By Drugs: Antithrombotics Dominate for Clot Prevention
Antithrombotic drugs lead at 60%, including antiplatelets and anticoagulants essential for preventing thrombus formation in ACS events.
Statin drugs follow at 25%, lowering cholesterol to stabilize plaques and reduce recurrence risk.
Antihypertensive drugs take 15%, controlling blood pressure to ease cardiac strain post-ACS.

-By End-User: Hospitals Command Acute Care
Hospitals hold the top share at 65%, central for emergency interventions, catheterization, and inpatient monitoring in ACS crises.
Specialty clinics capture 25%, focusing on cardiology follow-ups and risk management.
Others, including ambulatory centers, account for 10%, supporting outpatient rehab and diagnostics.

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Why is the Acute Coronary Syndrome Market Growing?
The rapid expansion of the Acute Coronary Syndrome (ACS) market in 2026 stems from rising cardiovascular disease burdens and healthcare innovations.​

-Rising Prevalence of Risk Factors
Increasing incidences of obesity, diabetes, hypertension, and smoking drive ACS cases, particularly among aging populations worldwide. The global geriatric demographic shift amplifies demand for ACS diagnostics and treatments. Lifestyle-associated disorders like high cholesterol further elevate the need for interventions.​

-Technological and Therapeutic Advances
Innovations in antiplatelet therapies, catheter-based procedures, and personalized medicine enhance treatment efficacy and patient outcomes. Novel biologics, thrombolytics, and minimally invasive options expand market opportunities. Improved diagnostic technologies enable earlier detection, boosting overall market dynamics.​

-Healthcare Infrastructure and Awareness
Enhanced healthcare spending and infrastructure in emerging markets improve ACS care access. Growing public awareness of heart health promotes timely interventions. Regional investments, especially in Asia-Pacific, accelerate commercialization of ACS therapies.​

Regional Insights:
-North America leads the Acute Coronary Syndrome (ACS) market with the largest share, accounting for approximately 42% of the global market in recent assessments, driven by advanced healthcare infrastructure, high prevalence of cardiovascular risk factors like obesity and diabetes, and widespread adoption of innovative diagnostics and therapies such as PCI and novel anticoagulants.​

-Europe follows closely with around 32% market share, supported by strong public health systems, early detection programs, and research collaborations that enhance treatment access across countries like Germany and the UK.​

-Asia Pacific holds about 18% of the market, experiencing the fastest growth due to rising healthcare investments, urbanization-induced lifestyle risks, and expanding cardiac care infrastructure in nations like China and India.​

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Key Players:
Teva Pharmaceuticals | Dr. Reddy's Laboratories | Boehringer Ingelheim | Johnson & Johnson | Merck | Novartis | Amgen Inc. | AbbVie Inc. | AstraZeneca PLC | GlaxoSmithKline Plc

Key Highlights (Top 5 Key Players) for Acute Coronary Syndrome Market:
-Teva Pharmaceuticals develops generic antiplatelet agents and anticoagulants, enabling affordable access to essential therapies like clopidogrel for preventing thrombotic events in ACS patients.

-Boehringer Ingelheim advances anti-thrombotic treatments such as rivaroxaban-based combinations, focusing on reducing recurrent ischemic risks post-ACS through pivotal trials like COMPASS.

-Johnson & Johnson (via Janssen) pioneered blockbuster anticoagulants like Xarelto (rivaroxaban), targeting factor Xa inhibition to lower stroke and mortality rates in high-risk ACS populations.

-AstraZeneca PLC drives innovation with Brilinta (ticagrelor), a P2Y12 inhibitor proven in PLATO trials to improve outcomes in ACS by enhancing platelet inhibition speed and reversibility.

-Novartis supports ACS management via lipid-lowering therapies like Inclisiran, an siRNA-based PCSK9 inhibitor that sustains LDL reductions to mitigate long-term cardiovascular complications.

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