Press release
Japan Powers Next-Generation Precision Healthcare as Genomic Medicine Market Enters High-Growth Era, Strengthening National Medical Innovation Leadership.
Tokyo-Japan- The Japan's Genomic medicine market is projected to grow at a CAGR of 14.6% from 2025 to 2035, driven by advancements in personalized medicine and sequencing technologies.Market growth is driven by the increasing prevalence of cancer and rare genetic disorders, rising focus on precision and personalized medicine, and expanding adoption of next-generation sequencing technologies across healthcare institutions in Japan. Additionally, strong government initiatives supporting genomic research, advancements in clinical genomics and precision oncology, increasing integration of AI-based genomic analysis, and improving reimbursement policies for genomic testing are further supporting market expansion.
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Japan: Key Industry Developments
✅ November 2025: Takeda Pharmaceutical advanced genomic-guided therapies for rare hereditary diseases, improving precision in treatment selection and enhancing patient outcomes, reinforcing its leadership role in Japan's genomic medicine sector.
✅ October 2025: Daiichi Sankyo launched expanded genomic sequencing programs for oncology patients to enable personalized therapy planning and strengthen precision oncology decision-making capabilities in clinical settings across Japan.
✅ September 2025: Sysmex Corporation introduced integrated genomic diagnostic platforms aimed at early cancer detection and ongoing patient monitoring, improving test accuracy and broadening clinical genomic applications in Japanese hospitals and labs.
✅ August 2025: Fujifilm Toyama Chemical rolled out gene-expression profiling tools designed to predict immunotherapy response, enhancing treatment efficacy and reinforcing precision genomics adoption in Japan.
✅ July 2025: Chugai Pharmaceutical expanded collaborations with biotech startups to accelerate next-generation genomic medicine innovation, boosting development pipelines for novel therapies in genetic and complex diseases.
Recent Key Approvals:-
Illumina's TruSight Oncology Comprehensive received MHLW approval on May 27 for comprehensive genomic profiling of over 500 genes in solid tumors, building on its FDA-approved status as the first distributable CGP IVD kit with pan-cancer companion diagnostics. Guardant Health Japan secured approval on December 21 for Guardant360 CDx, the first blood-based companion diagnostic for genomic profiling, aiding targeted therapies and trials.
Market Impact
These approvals address Japan's drug lag, with PMDA streamlining reviews for gene therapies and oncology drugs amid 43 anticipated novel approvals. They support genomic integration in cancer care, driven by partnerships and infrastructure investments
Market Segmentation Analysis:
By Technology
- CRISPR/Cas9 dominates with 44.14% market share in 2024, favored for its precision, cost-effectiveness, and versatility in research and therapeutics across biotech and pharma sectors.
- Other technologies like TALENs and base editors hold the balance, supporting niche applications in gene therapy development and agricultural biotech.
By Delivery Method
- In vivo genome editing leads at 50.63% share in 2024, driven by investments in direct gene therapies using vectors like AAVs for inherited diseases and cancers.
- Ex vivo methods follow, gaining from cell-based therapies but limited by scalability challenges in Japan's clinical infrastructure.
By Application
- Genetic engineering commands 73.16% share in 2024, powering disease modeling, functional genomics, and precision breeding in agriculture.
- Therapeutics and diagnostics contribute smaller portions, with oncology and rare diseases as key growth areas amid Japan's aging population.
By End-User
- Biotechnology and pharmaceutical companies hold 49.66% share in 2024, leading through R&D pipelines and collaborations for drug discovery.
- Academic and research institutions trail, bolstered by government-funded genome projects, while hospitals expand via clinical adoption.
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Growth Drivers:
Advancements in Genomic Technologies
Rapid improvements in sequencing technologies like next-generation sequencing (NGS), gene expression profiling, and integrated genomic diagnostic platforms are enhancing test accuracy, speed, and clinical utility, which boosts adoption in hospitals and research institutions across Japan.
Personalized and Precision Medicine Adoption
Growing demand for personalized care, especially in oncology, rare diseases, and pharmacogenomics, is driving the integration of genomic data into treatment decision-making, enabling tailored therapies and improving patient outcomes.
Strong Government Support & Funding Initiatives
Strategic national programs, funding for genomic research, and supportive regulatory frameworks (e.g., precision medicine initiatives and cancer genomic promotion plans) are fostering innovation, collaboration, and clinical implementation of genomic medicine technologies.
Aging Population & Rising Disease Burden
Japan's rapidly aging demographics and increasing prevalence of genetic disorders, cancer, and chronic diseases are significantly raising the clinical demand for genomic testing and personalized therapeutic approaches.
Academic-Industry Collaboration & Research Ecosystem
Partnerships between hospitals, biotech firms, universities, and research centers accelerate innovation, facilitate data sharing, and support the development of novel genomic applications, strengthening Japan's overall genomic medicine ecosystem.
Regional Insights:
Kanto region (Tokyo, Kanagawa, Saitama, Chiba) holds the dominant share of Japan's genomic medicine market, driven by the concentration of leading national research institutions, major university hospitals, advanced sequencing facilities, and biotech companies. Tokyo serves as the core hub for precision medicine programs, large-scale genome databases, and government-backed initiatives, supported by strong funding, clinical trial activity, and rapid adoption of NGS-based diagnostics in oncology and rare diseases.
Kansai region (Osaka, Kyoto, Hyogo) stands as the second-largest contributor, supported by world-class medical universities, pharmaceutical innovation clusters, and active participation in regenerative medicine, rare disease genomics, and cancer genome profiling projects. The presence of major pharma companies, clinical research centers, and patient registries strengthens deployment of personalized treatment approaches, though market size estimates vary across assessments.
Chubu region (Aichi, Nagoya and surrounding prefectures) represents a steadily expanding genomic medicine hub, fueled by growing investments in medical innovation, hospital-based genetic testing programs, and collaborations between universities and industry for precision oncology and hereditary disease studies. Rising diagnostic adoption and strengthening healthcare infrastructure are supporting gradual yet consistent market expansion in this region.
Kyushu & Okinawa region is emerging as a high-growth area, driven by increasing participation in national genome research frameworks, growing hospital capabilities in advanced diagnostics, and supportive regional innovation policies. Expanding access to genomic testing, especially in cancer care and inherited disease screening, is expected to accelerate market penetration over the coming years.
Hokkaido & Tohoku region demonstrates developing yet promising market potential, supported by academic research centers, improving genomic testing infrastructure, and increasing awareness of precision medicine. Although the region currently trails major metropolitan clusters in adoption levels, government-supported healthcare digitization, regional innovation programs, and broader clinical integration of genomic diagnostics are gradually enhancing growth prospects.
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Key Players:
RIKEN GENESIS CO., LTD., Chugai Pharmaceutical Co., Ltd., Illumina, Inc., QIAGEN, Agilent Technologies, Inc., Thermo Fisher Scientific Inc., Oxford Nanopore Technologies plc., Takara Bio Inc, and Eurofins Scientific.
Key Highlights (Top 5 Key Players) :
RIKEN GENESIS CO., LTD. leads Japan's genomic medicine with clinical sequencing services, BNA nucleic acid tech, and genetic analysis support for pharma development and diagnostics.
Chugai Pharmaceutical Co., Ltd., a Roche subsidiary, drives genomic therapies via biotech partnerships, next-gen medicines, and precision oncology innovations in Japan.
Illumina, Inc. dominates with next-generation sequencing platforms, enabling rapid genetic analysis for personalized medicine and research in Japan's genomic market.
QIAGEN provides molecular diagnostics, sample prep kits, and NGS workflows, supporting genomic profiling and clinical applications across Japanese healthcare.
Takara Bio Inc. excels in gene editing tools, PCR reagents, and sequencing services, advancing biotech R&D and genomic medicine in Japan.
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