Presbyopia Pipeline 2025: Key Companies, MOA, ROA, and Clinical Trials Evaluation by DelveInsight

(Las Vegas, Nevada, United States) As per DelveInsight's assessment, globally, Presbyopia pipeline constitutes 6+ key companies continuously working towards developing 6+ Presbyopia treatment therapies, analysis of Clinical Trials, Therapies, Mechanism of Action, Route of Administration, and Developments analyzes DelveInsight.

"Presbyopia Pipeline Insight, 2025" report by DelveInsight outlines comprehensive insights into the present clinical development scenario and growth prospects across the Presbyopia Market.

The Presbyopia Pipeline report embraces in-depth commercial and clinical assessment of the pipeline products from the pre-clinical developmental phase to the marketed phase. The report also covers a detailed description of the drug, including the mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, collaborations, mergers acquisition, funding, designations, and other product-related details.

Some of the key takeaways from the Presbyopia Pipeline Report: https://www.delveinsight.com/sample-request/presbyopia-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=gpr
• Companies across the globe are diligently working toward developing novel Presbyopia treatment therapies with a considerable amount of success over the years.
• Presbyopia companies working in the treatment market are Cellix Bio, Plex Pharmaceuticals, Santen Pharmaceutical, Glaukos Corporation, Ocuphire Pharma, Visus Therapeutics, LENZ Therapeutics, Eyenovia, Orasis Pharmaceuticals, Ocuphire Pharma, AbbVie, and others, are developing therapies for the Presbyopia treatment
• Emerging Presbyopia therapies in the different phases of clinical trials are- CLX-OPH-162, Research programme, STN 1013600, GLK-302, Nyxol, VTI-001, LNZ100, MicroLine (Pilocarpine Ophthalmic), CSF-1 (PresbiDrops), Nyxol, VT-101 (Brimochol), AGN-241622, and others are expected to have a significant impact on the Presbyopia market in the coming years.
• In December 2025, LENZ Therapeutics and Lotus Pharmaceutical announced that Lotus has filed a New Drug Application (NDA) with the Ministry of Food and Drug Safety (MFDS) in South Korea seeking approval of VIZZ for treating presbyopia in adults. This marks the first regulatory submission under the exclusive licensing and commercialization agreement for South Korea that the two companies finalized in May 2025.
• In October 2025, LENZ Therapeutics announced the U.S. availability of VIZZ, the first and only FDA-approved aceclidine-based eye drop for treating presbyopia in adults. Nationwide sample distribution to eye care professionals has begun, with commercial shipments to consumers set to start in October. This launch establishes LENZ as a significant player in the sizable and previously underserved U.S. presbyopia market, with clinical trials demonstrating rapid and lasting near-vision improvement for most patients.
• In April 2025, Tenpoint Therapeutics, Ltd. ("Tenpoint"), a global clinical-stage biotech company dedicated to pioneering therapies that restore vision in aging eyes, has announced the submission of a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) for BRIMOCHOLTM PF. The drug is intended for the treatment of presbyopia, an age-related condition that causes near-vision loss and affects around two billion people worldwide, including 128 million in the United States.
• In January 2025, Tenpoint Therapeutics, Inc., a global clinical-stage biotechnology company focused on innovative therapies to restore vision in aging eyes, announced encouraging topline results from its second Phase 3 pivotal trial, BRIO-II. The trial successfully met the pre-determined primary endpoints established in collaboration with the U.S. FDA, European Medicines Agency (EMA), and the UK's Medicines and Healthcare products Regulatory Agency (MHRA).
• In September 2024, Ocuphire Pharma, Inc. (Nasdaq: OCUP), a clinical-stage biopharmaceutical company specializing in small-molecule therapies for retinal and refractive eye disorders, announced the initiation of the VEGA-3 Phase 3 clinical trial. The study, evaluating Phentolamine Ophthalmic Solution 0.75% for the treatment of presbyopia, has commenced dosing its first participants.

Presbyopia Overview
Age-related presbyopia is a condition that results in blurry near vision. It usually manifests around the age of 40 and affects all people, including those who have never experienced visual issues previously. Presbyopia is a disorder of the eyes when the eye gradually loses its ability to concentrate quickly on nearby things.

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Emerging Presbyopia Drugs Under Different Phases of Clinical Development Include:
• CLX-OPH-162: Cellix Bio
• Research programme: Plex Pharmaceuticals
• STN 1013600: Santen Pharmaceutical
• GLK-302: Glaukos Corporation
• Nyxol: Ocuphire Pharma
• VTI-001: Visus Therapeutics
• LNZ100: LENZ Therapeutics
• MicroLine (Pilocarpine Ophthalmic): Eyenovia
• CSF-1 (PresbiDrops): Orasis Pharmaceuticals
• Nyxol: Ocuphire Pharma
• VT-101 (Brimochol): Visus Therapeutics
• AGN-241622: AbbVie

Presbyopia Route of Administration
Presbyopia pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs, such as
• Inhalation
• Inhalation/Intravenous/Oral
• Intranasal
• Intravenous
• Intravenous/ Subcutaneous
• NA
• Oral
• Oral/intranasal/subcutaneous
• Parenteral
• Subcutaneous

Presbyopia Molecule Type
Presbyopia Products have been categorized under various Molecule types, such as
• Antibody
• Antisense oligonucleotides
• Immunotherapy
• Monoclonal antibody
• Peptides
• Protein
• Recombinant protein
• Small molecule
• Stem Cell
• Vaccine

Presbyopia Pipeline Therapeutics Assessment
• Presbyopia Assessment by Product Type
• Presbyopia By Stage and Product Type
• Presbyopia Assessment by Route of Administration
• Presbyopia By Stage and Route of Administration
• Presbyopia Assessment by Molecule Type
• Presbyopia by Stage and Molecule Type

DelveInsight's Presbyopia Report covers around 6+ products under different phases of clinical development like
• Late-stage products (Phase III)
• Mid-stage products (Phase II)
• Early-stage product (Phase I)
• Pre-clinical and Discovery stage candidates
• Discontinued & Inactive candidates
• Route of Administration

Further Presbyopia product details are provided in the report. Download the Presbyopia pipeline report to learn more about the emerging Presbyopia therapies
https://www.delveinsight.com/sample-request/presbyopia-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=gpr

Some of the key companies in the Presbyopia Therapeutics Market include:
Key companies developing therapies for Presbyopia are - Eyenovia, Orasis Pharmaceuticals, Ocuphire Pharma, Visus Therapeutics, LENZ Therapeutics, Glaukos Corporation, AbbVie, and others.

Presbyopia Pipeline Analysis:
The Presbyopia pipeline report provides insights into
• The report provides detailed insights about companies that are developing therapies for the treatment of Presbyopia with aggregate therapies developed by each company for the same.
• It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Presbyopia Treatment.
• Presbyopia key companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
• Presbyopia Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.
• Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the Presbyopia market.
The report is built using data and information traced from the researcher's proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations, and featured press releases from company/university websites and industry-specific third-party sources, etc.

Download Sample PDF Report to know more about Presbyopia drugs and therapies
https://www.delveinsight.com/sample-request/presbyopia-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=gpr

Presbyopia Pipeline Market Drivers
• Increasing Prevalence of Presbyopia, increase in research and developmental activities are some of the important factors that are fueling the Presbyopia Market.

Presbyopia Pipeline Market Barriers
• However, high-cost associated with the disease, lack of healthcare infrastructure and other factors are creating obstacles in the Presbyopia Market growth.

Scope of Presbyopia Pipeline Drug Insight
• Coverage: Global
• Key Presbyopia Companies: Cellix Bio, Plex Pharmaceuticals, Santen Pharmaceutical, Glaukos Corporation, Ocuphire Pharma, Visus Therapeutics, LENZ Therapeutics, Eyenovia, Orasis Pharmaceuticals, Ocuphire Pharma, AbbVie, and others
• Key Presbyopia Therapies: CLX-OPH-162, Research programme, STN 1013600, GLK-302, Nyxol, VTI-001, LNZ100, MicroLine (Pilocarpine Ophthalmic), CSF-1 (PresbiDrops), Nyxol, VT-101 (Brimochol), AGN-241622, and others
• Presbyopia Therapeutic Assessment: Presbyopia current marketed and Presbyopia emerging therapies
• Presbyopia Market Dynamics: Presbyopia market drivers and Presbyopia market barriers

Contact Us:
Gaurav Bora
gbora@delveinsight.com
+14699457679
Healthcare Consulting
https://www.delveinsight.com/consulting-services

About DelveInsight
DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance. It also offers Healthcare Consulting Services, which benefits in market analysis to accelerate business growth and overcome challenges with a practical approach.

This release was published on openPR.