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Exocrine Pancreatic Insufficiency (EPI) Market CAGR of around 5.9%
Exocrine Pancreatic Insufficiency (EPI) Market
The Exocrine Pancreatic Insufficiency (EPI) Market was valued at USD 3.4 billion in 2024 and is projected to reach USD 5.8 billion by 2034, growing at a CAGR of around 5.9%. Growth is driven by increasing prevalence of chronic pancreatitis, cystic fibrosis, and other digestive disorders, along with rising demand for pancreatic enzyme replacement therapies (PERT).
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Key Market Drivers
• Growing incidence of EPI from chronic pancreatitis and cystic fibrosis.
• Rising adoption of pancreatic enzyme replacement therapy (PERT) to improve digestion and nutrient absorption.
• Advancements in diagnostic tools like fecal elastase testing improving early detection.
• Increasing healthcare awareness and expanded gastroenterology care networks.
Challenges
• Long-term therapy adherence concerns.
• High cost of enzyme replacement products.
• Underdiagnosis in some regions due to nonspecific symptoms.
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Market Segmentation
By Treatment
• Pancreatic enzyme replacement therapy (PERT)
• Acid suppressants (PPIs/H2 blockers, adjunctive)
• Nutritional supplements
By Diagnosis
• Fecal elastase testing
• Serum tests (amylase/lipase)
• Imaging (MRI/CT/ultrasound)
• Breath tests
By End User
• Hospitals
• Gastroenterology clinics
• Specialty digestive disorder centers
• Homecare settings
By Distribution Channel
• Hospital pharmacies
• Retail pharmacies
• Online pharmacies
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Regional Snapshot
• North America leads due to high diagnostic rates, strong PERT uptake, and advanced GI care access.
• Europe shows steady growth backed by structured digestive disease management.
• Asia-Pacific is the fastest-growing region with rising awareness and expanding healthcare infrastructure.
Key Companies
AbbVie, Takeda, Allergan, Mylan, Nestlé Health Science, Sanofi, GSK (nutritional divisions), Fresenius Kabi.
Future Outlook
The EPI market will continue expanding with enhanced enzyme formulations, wider use of combination therapies, and improved early diagnosis. Growth in chronic pancreatitis and cystic fibrosis treatment programs, along with digital health management tools, will further support long-term market adoption.
This report is also available in the following languages : Japanese (膵外分泌機能不全市場), Korean (외분비 췌장 부전 시장), Chinese (外分泌性胰腺功能不全市场), French (Marché de l'insuffisance pancréatique exocrine), German (Markt für exokrine Pankreasinsuffizienz), and Italian (Mercato dell'insufficienza pancreatica esocrina), etc.
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