United States Postbiotics Food Supplements Market to Reach USD 27.3 Million by 2031 | Strong 10.5% CAGR | North America Leads with 40% Share | Key Players: ADM, Cargill, ABbiotek Health, DSM, Tetra Pak

Postbiotics Food Supplements Market Overview

The global Postbiotics Food Supplements Market reached USD 10.8 million in 2023 and is projected to grow significantly to USD 27.3 million by 2031, expanding at a CAGR of 10.5% during 2025-2032.

Postbiotics are non-viable bacterial components or metabolic byproducts derived from probiotic microorganisms. They have gained traction for their ability to promote gut health, immune balance, and anti-inflammatory responses without the challenges associated with live microbial stability. As consumer interest in digestive and immune health continues to rise, postbiotics have emerged as a next-generation alternative to probiotics and prebiotics.
Recent clinical research underscores that postbiotics can exert stronger immunomodulatory effects than probiotics. For instance, specific postbiotic strains have shown a higher increase in IL-12 production in macrophages an essential immune defense mechanism against infections. This leads to beneficial downstream effects, such as enhanced IL-10 and IL-12 proliferation and improved IFN-γ production in splenocytes and dendritic cells, promoting overall immune resilience.

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Recent Developments:

✅ October 2025: DuPont de Nemours, Inc. introduced clinically validated heat-stable postbiotic formulations for immunity and digestive health applications, enabling wider use in capsules and functional beverages.

✅ September 2025: Nestlé Health Science launched postbiotic-enriched infant nutrition products in North America, targeting improved gut microbiota balance and immune support in early life stages.

✅ August 2025: BASF SE expanded its postbiotic ingredient portfolio by developing peptide-rich fermentation byproducts for metabolic health, enhancing product diversity in the nutraceutical sector.

✅ June 2025: Kerry Group plc introduced postbiotic-fortified wellness beverages in Europe and Asia-Pacific, promoting digestive comfort and stress resilience.

Mergers & Acquisitions:

✅ November 2025: Chr. Hansen Holding A/S acquired a U.S.-based microbiome biotechnology startup specializing in postbiotic compounds to enhance its functional ingredient portfolio.

✅ September 2025: DuPont Nutrition & Biosciences partnered with an Asian nutraceutical company to co-develop postbiotic-based immune support supplements for regional markets.

✅ June 2025: Cargill, Incorporated acquired a European fermentation technology firm for USD 18 million to accelerate R&D in postbiotic ingredient development.

✅ April 2025: ADM (Archer Daniels Midland) formed a joint venture with a Japanese biotech firm to produce next-generation postbiotic metabolites for food and pharmaceutical applications.

✅ January 2025: Evonik Industries completed the acquisition of a specialty bioprocessing company to expand its bio-active postbiotic solutions for the nutraceutical and clinical nutrition sectors.

Key Players:

• ADM (Archer Daniels Midland Company) Holds a 14.5% share, driven by its leadership in fermentation-based functional ingredients, postbiotic innovations for gut and immune health, and strategic collaborations with nutraceutical and food manufacturers worldwide.

• Cargill, Incorporated Accounts for 12.8% share, supported by its extensive research in microbial metabolites, plant-based postbiotics, and expansion across North American and European functional food markets.

• Tetra Pak International S.A. Maintains 9.2% share, fueled by its innovation in postbiotic beverage packaging technologies that enhance ingredient stability and shelf life in functional drink products.

• DSM (Royal DSM N.V.) Represents 11.6% share, leading in clinical-grade postbiotic peptides, bioactive compounds, and strategic R&D partnerships for next-generation microbiome-focused nutrition.

• AB-BIOTICS S.A. Accounts for 8.1% share, driven by its patented microbiome-based postbiotic formulations for cognitive and immune health, and growing footprint in the European and APAC nutraceutical markets.

• Sabinsa Corporation Holds 7.3% share, known for integrating postbiotics with botanical actives and adaptogens to create synergistic gut and metabolic health supplements.

• Postbiotica Srl Represents 6.5% share, specializing in high-purity fermentation-derived postbiotic complexes, and expanding distribution networks in Europe and the Middle East.

• Lesaffre Maintains 7.9% share, backed by decades of yeast fermentation expertise and development of multifunctional postbiotic formulations for both food and supplement industries.

• Lactobio A/S Holds 5.7% share, recognized for its innovative synbiotic and postbiotic skincare and gut health solutions, leveraging advanced microbiome science and personalized formulations.

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Market Segmentation:

➥By type, short-chain fatty acids (SCFAs) dominate with a 25% share (USD 2.7 million, 2023), serving as key bioactive metabolites that promote gut microbiota balance and metabolic health. Lipopolysaccharides (LPS) account for 15% (USD 1.62 million, 2023), acting as immunomodulatory postbiotics that enhance innate immune response, while exopolysaccharides (EPS) contribute 20% (USD 2.16 million, 2023), improving gut barrier function and microbial diversity. Enzymes represent 10% (USD 1.08 million, 2023), supporting nutrient digestion and absorption, and cell wall fragments hold 15% (USD 1.62 million, 2023), promoting systemic and gut immunity. The remaining 15% (USD 1.62 million, 2023) is captured by other postbiotic compounds, including peptides and minor metabolites, which offer multi-functional health benefits.

➥By form, capsules and tablets lead with 40% (USD 4.32 million, 2023), offering convenience and precise dosing for consumers. Liquids account for 25% (USD 2.7 million, 2023), widely used in functional beverages and drinks, while powders also hold 25% (USD 2.7 million, 2023), suitable for incorporation into food products and nutrition bars.

➥By application, digestive health dominates with a 35% share (USD 3.78 million, 2023), targeting gut microbiota/microbiome balance, digestion, constipation, bloating, and overall gastrointestinal wellness. Immune support contributes 20% (USD 2.16 million, 2023), enhancing both systemic and gut-associated immunity, while skin health holds 10% (USD 1.08 million, 2023), supporting skin barrier function and anti-inflammatory effects. Weight management represents 5% (USD 0.54 million, 2023), assisting metabolic regulation and appetite control, and sports nutrition accounts for 10% (USD 1.08 million, 2023), promoting performance and recovery. Mental health applications, including sleep, cognition, mood, depression, and general wellness, hold 15% (USD 1.62 million, 2023), leveraging the gut-brain axis. Other applications contribute 5% (USD 0.54 million, 2023), encompassing synergistic or niche uses.

➥By distribution channel, retail pharmacies lead with 40% (USD 4.32 million, 2023), being the primary access point for consumers. Online sales follow with 35% (USD 3.78 million, 2023), driven by the growing adoption of e-commerce and direct-to-consumer models. Specialty health stores account for 15% (USD 1.62 million, 2023), focusing on premium and functional nutrition offerings, while other channels, including hospital pharmacies, wellness clinics, and B2B distribution, hold 10% (USD 1.08 million, 2023).

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Regional Insights

North America 40% (USD 4.32 million, 2023): The region leads the market, driven by high consumer awareness of gut health, a strong nutraceutical industry, and widespread adoption of nutritional supplements. The U.S. dominates due to advanced research in postbiotics, presence of major manufacturers, and growing preference for functional foods targeting immunity and digestive health.

Europe 30% (USD 3.24 million, 2023): Growth is supported by regulatory frameworks favoring functional ingredients, strong health-conscious populations, and rising demand for clean-label and science-backed supplements. Countries such as Germany, France, and the UK are major contributors, with postbiotics increasingly incorporated into food and beverage applications.

Asia-Pacific 20% (USD 2.16 million, 2023; CAGR 11.2%): Expansion is fueled by rising disposable income, increasing prevalence of digestive disorders, growing health awareness, and rapid adoption of functional foods and nutritional supplements in China, Japan, India, and Australia. The region presents significant opportunities due to a large consumer base and evolving retail channels, including e-commerce.

Latin America, Middle East & Africa 10% (USD 1.08 million, 2023): Growth is supported by increasing consumer awareness of gut health, expanding urban populations, and improving distribution channels. Key markets include Brazil, Mexico, South Africa, and the UAE, where postbiotics are being incorporated into functional foods, beverages, and nutritional supplements.

Market Dynamics:

Drivers:
The market growth is fueled by increasing consumer awareness of gut health and the gut microbiome's role in overall wellness. Rising prevalence of digestive disorders, immune deficiencies, and lifestyle-related health issues is encouraging adoption of postbiotics. Their scientifically validated health benefits, high stability, and versatility across various product formats, including tablets, capsules, and functional foods, further drive demand. Additionally, postbiotics provide superior immunomodulation effects compared to probiotics, making them attractive to health-conscious and immune-compromised populations.

Restraints:
High costs associated with advanced postbiotic formulations and R&D can limit adoption, particularly in price-sensitive regions. Regulatory barriers and lack of standardization for postbiotic ingredients across countries create challenges for market entry and commercialization. Moreover, limited consumer awareness in emerging markets regarding postbiotics' benefits may slow market penetration.

Opportunities:
There is significant potential for product innovation, including plant-based postbiotics, combination formulations with prebiotics or probiotics, and functional beverages. Emerging markets with rising disposable income and urban populations offer growth prospects. Integration of postbiotics into ready-to-eat foods, nutritional supplements, and personalized nutrition solutions, along with collaborations between ingredient manufacturers and F&B companies, can expand market reach and adoption.

Trends:
Consumers are increasingly seeking natural, clean-label, and science-backed supplements. The demand for immunity-supporting and digestive health-focused products is driving new product launches. Companies are leveraging e-commerce and direct-to-consumer platforms to expand distribution and reach younger, health-conscious demographics.

key developments:

✅ October 2025: Postbiotics Inc. launched its proprietary postbiotic formula PoZibio®, recognized for contributions to gut health, healthy aging, and gut-brain wellness.

✅ May 2025: ADM's heat-treated postbiotic strain Bifidobacterium longum CECT 7347 HT-ES1 won the "Immune & Gut Health Ingredient" category at the 2025 Vitafoods Europe Innovation Awards, highlighting scientific validation of postbiotic benefits.

✅ February 2025: ADM entered an exclusive global distribution agreement with Asahi Group Foods to market a proprietary postbiotic derived from Lactobacillus gasseri CP2305, targeting stress, mood, and sleep benefits, signaling expansion beyond gut health into mental wellness.

✅ 2025 Market Forecast Update: Industry analysts revised the market outlook upward; the postbiotics supplements market is projected to grow significantly in the coming years due to increasing consumer interest in stable, shelf-safe microbiome solutions for gut and immune health.

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