Press release
Global Osteoarthritis Therapeutics Market to Hit USD 22.85Bn by 2035
Osteoarthritis (OA) is a degenerative joint disease characterized by the gradual breakdown of cartilage, leading to pain, stiffness, and limited mobility. The rising prevalence of OA globally, especially among the aging population, has made the osteoarthritis therapeutics market a critical segment in musculoskeletal healthcare. Patients are increasingly seeking therapies that reduce pain, improve joint function, and delay the need for surgical interventions.
The global osteoarthritis therapeutics market was valued at USD 9.92 Billion in 2025 and is projected to grow at a CAGR of 8.70%, reaching USD 22.85 Billion by 2035. The market growth is driven by a combination of factors, including:
Increasing prevalence of osteoarthritis in developed and emerging economies
Rising geriatric population globally
Growing awareness and diagnosis of OA
Expansion of healthcare infrastructure
Innovation in therapeutic interventions and drug delivery methods
This report explores the market landscape, including drug classes, dosage forms, routes of administration, end users, distribution channels, regional trends, and key companies.
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Market Breakup by Type of Osteoarthritis
Osteoarthritis affects multiple joints, and therapeutic approaches are tailored accordingly. The market is segmented by disease type as follows:
Hip Osteoarthritis
Hip OA is associated with pain in the hip joint and reduced mobility. Treatments include:
NSAIDs for pain management
Corticosteroid injections
Hyaluronic acid injections
Emerging regenerative therapies
Spinal Osteoarthritis
Spinal OA affects vertebral joints and can lead to chronic back pain. Treatments commonly involve:
Analgesics and NSAIDs
Parenteral corticosteroids
Physical therapy adjuncts
Knee Osteoarthritis
Knee OA is the most prevalent form globally, leading to pain and mobility limitations. Treatments include:
Oral NSAIDs and other analgesics
Intra-articular corticosteroids or hyaluronic acid injections
Topical creams and gels
Hand Osteoarthritis
Hand OA is common among older adults and impacts fine motor functions. Management typically involves:
Oral and topical NSAIDs
Analgesic creams and gels
Non-pharmacological interventions
Others
Other joint-related OA includes shoulder, ankle, and foot osteoarthritis. Treatments are personalized based on severity and patient condition.
Market Breakup by Drug Class
The osteoarthritis therapeutics market is segmented into multiple drug classes, each targeting different aspects of disease management:
Nonsteroidal Anti-inflammatory Drugs (NSAIDs)
Most widely used for pain relief and inflammation control
Available in oral and topical forms
Other Analgesics
Acetaminophen and combination therapies
Provide mild to moderate pain relief
Corticosteroids
Injectable formulations for localized joint inflammation
Often used in combination with physical therapy
Hyaluronic Acid Injections
Used for cartilage lubrication and joint cushioning
Increasing adoption in knee and hip OA management
Others
Disease-modifying OA drugs (DMOADs) in clinical development
Emerging biologics and regenerative therapies
Market Breakup by Dosage Form
Osteoarthritis therapeutics are administered through various dosage forms tailored to patient needs and disease severity:
Tablets and Capsules
Commonly used for NSAIDs and other analgesics
Oral administration is preferred for chronic management
Injections
Corticosteroids and hyaluronic acid are mainly administered via intra-articular injections
Provide targeted pain relief and improve joint mobility
Creams and Gels
Topical analgesics reduce systemic side effects
Frequently used for hand and knee OA
Others
Emerging delivery systems include patches, inhalable analgesics, and combination therapies
Market Breakup by Route of Administration
Route of administration is critical in determining therapeutic efficacy and patient compliance:
Oral
Widely preferred for NSAIDs and other analgesics
Advantages: ease of use, systemic relief
Parenteral
Includes intra-articular injections and intravenous formulations
Provides localized or rapid relief
Topical
Creams, gels, and patches applied directly to the affected joint
Minimizes systemic exposure and side effects
Market Breakup by End User
End users in the osteoarthritis therapeutics market include healthcare institutions, clinics, and homecare settings:
Hospitals
Major contributors due to high patient volume and complex cases
Use of injectable therapies and advanced therapeutics
Specialty Clinics
Focus on orthopaedics, rheumatology, and pain management
Provide targeted OA treatments including injections and physiotherapy adjuncts
Homecare Settings
Oral medications, topical creams, and self-administered therapies
Increasing demand due to convenience and aging population
Others
Rehabilitation centers and outpatient facilities
Growing adoption of non-invasive therapies
Read the Full Report with the Table of Contents - https://www.expertmarketresearch.com/reports/osteoarthritis-therapeutics-market.
Market Breakup by Distribution Channel
The distribution channels for osteoarthritis therapeutics ensure widespread access:
Hospital Pharmacies
Key suppliers for injectable therapies and prescription medications
Retail Pharmacies
Widely used for oral NSAIDs, analgesics, and topical formulations
Online Pharmacies
Rising trend due to convenience, home delivery, and increasing e-health adoption
Others
Specialized distributors and medical supply chains
Market Breakup by Region
United States
Largest market in North America
High prevalence of OA, growing geriatric population
Advanced healthcare infrastructure supports complex therapeutics
EU-4 and the United Kingdom
Includes Germany, France, Italy, Spain, and the UK
Rising awareness and advanced treatment protocols
Adoption of hyaluronic acid and corticosteroid injections
Japan
Increasing prevalence of OA due to aging population
Strong R&D focus on regenerative therapies
India
Expanding healthcare infrastructure and increasing OA prevalence
Rising availability of oral NSAIDs and injectable therapies
Trends and Opportunities in the Osteoarthritis Therapeutics Market
Growth of Biologics and Regenerative Medicine
Focus on disease-modifying OA drugs (DMOADs)
Stem-cell-based and gene therapies in clinical trials
Increasing Preference for Minimally Invasive Treatments
Intra-articular injections gaining traction
Reduces need for surgical interventions
Rising Online Pharmacy Penetration
Patients increasingly prefer home delivery of oral and topical therapeutics
Combination Therapies
NSAIDs with topical analgesics or hyaluronic acid injections improve patient outcomes
Expansion in Emerging Economies
India, Brazil, and Mexico present growth opportunities
Rising healthcare spending and awareness
Challenges Facing the Market
High Cost of Advanced Therapeutics
Injectable biologics and regenerative therapies are expensive
Side Effects of Long-Term NSAID Use
Gastrointestinal, cardiovascular, and renal risks
Drives demand for safer alternatives
Stringent Regulatory Requirements
Delays approval of new drugs and biologics
Patient Compliance Issues
Complex dosing schedules and injectable therapies can affect adherence
Key Companies Covered in the Market
Sanofi
Bayer AG
Haleon plc
Seikagaku Corporation
Bristol Myers Squibb
Ono Pharmaceutical
Novartis AG
Pfizer Inc.
Assertio Holdings
Pacira Biosciences Inc.
Anika Therapeutics Inc.
Bioventus LLC
These companies are focusing on product innovation, partnerships, and R&D to develop next-generation OA therapeutics and expand their market share.
Future Outlook (2026-2035)
The osteoarthritis therapeutics market is expected to grow steadily due to:
Aging populations in developed countries
Increasing prevalence of knee and hip OA
Adoption of regenerative medicine and biologics
Expansion of homecare and outpatient treatment options
Growing online and retail pharmacy distribution networks
By 2035, the market is projected to reach USD 22.85 Billion, supported by increasing clinical research, patient awareness, and innovative therapeutics.
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