Knee Replacement Market to Hit USD 16.72 Billion by 2033 at 4.8% CAGR | North America Leads with 42% Regional Share

The Global Knee Replacement Market reached US$ 10.85 billion in 2024 and is projected to reach US$ 16.72 billion by 2033, expanding at a CAGR of 4.8% during the forecast period 2025-2033, according to the DataM Intelligence report. Market growth is driven by the rising prevalence of osteoarthritis, an aging population, and increasing demand for advanced joint reconstruction procedures. Improvements in implant materials, surgical robotics, and minimally invasive knee replacement techniques are further supporting wider adoption and enhancing patient outcomes.

Knee replacement devices are specialized medical implants designed to replace damaged or deteriorated portions of the knee joint resulting from conditions such as osteoarthritis, rheumatoid arthritis, or traumatic injuries. These devices are intended to reduce pain, restore mobility, and improve overall knee function. They are widely used in total knee arthroplasty, partial knee replacement, and revision surgeries, offering patients long-term durability and improved quality of life.

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The Knee Replacement Market refers to the industry that provides implants, surgical tools, and technologies used to replace damaged knee joints and restore mobility in patients with severe arthritis or injury.

Key Developments
✅ October 2025: Leading orthopedic device manufacturers launched next-generation robotic-assisted knee replacement systems to improve surgical precision and reduce recovery times.

✅ September 2025: Hospitals in the U.S. and Europe expanded adoption of AI-powered preoperative planning software to enhance implant selection and patient-specific alignment strategies.

✅ August 2025: Major implant companies introduced lightweight, high-durability knee prosthetics using advanced biomaterials such as titanium alloys and 3D-printed porous metals.

✅ July 2025: Research institutions initiated large-scale studies evaluating outcomes of cementless knee implants among younger and active patient populations.

✅ May 2025: Ambulatory surgical centers (ASCs) reported significant growth in outpatient knee replacement procedures due to minimally invasive surgical advancements.

✅ March 2025: Asia-Pacific hospitals increased investments in digital rehabilitation tools and remote physiotherapy platforms to support enhanced post-operative recovery for knee replacement patients.

Mergers & Acquisition
✅ November 2025: A global orthopedic technology company acquired a robotics startup specializing in AI-assisted joint replacement navigation systems to strengthen its surgical robotics portfolio.

✅ August 2025: A prominent implant manufacturer partnered with a European medtech firm to co-develop smart sensor-enabled knee implants for real-time mobility and load tracking.

✅ June 2025: An orthopedic solutions provider acquired a medical imaging and planning software company to integrate advanced preoperative analytics into its knee replacement ecosystem.

Key Players
Zimmer Biomet Holdings, Inc. | Stryker Corporation | DePuy Synthes (Johnson & Johnson) | Smith & Nephew Plc | B. Braun Melsungen AG | Medtronic Plc | MicroPort Scientific Corporation | Exactech, Inc. | Conformis, Inc. | DJO Global, Inc.

Key Highlights
Zimmer Biomet Holdings, Inc. - Holds a 17.4% share, driven by its extensive orthopedic implant portfolio, advanced joint reconstruction technologies, and strong global distribution network.

Stryker Corporation - Holds a 16.1% share, supported by innovative robotic-assisted surgical systems, trauma implants, and leadership in advanced orthopedic devices.

DePuy Synthes (Johnson & Johnson) - Holds a 15.3% share, fueled by a broad range of joint reconstruction, spine, and trauma products supported by strong clinical research and global adoption.

Smith & Nephew Plc - Holds a 10.2% share, backed by its strong knee and hip implant systems, sports medicine solutions, and expanding presence in minimally invasive orthopedics.

B. Braun Melsungen AG - Holds an 8.9% share, driven by high-quality orthopedic implants, surgical instruments, and advanced therapy systems.

Medtronic Plc - Holds an 8.1% share, supported by its spine and orthopedic technologies, continuous innovation, and strong hospital partnerships.

MicroPort Scientific Corporation - Holds a 6.3% share, strengthened by its growing orthopedic implant business, competitive pricing, and expanding presence in Europe and Asia.

Exactech, Inc. - Holds a 5.2% share, recognized for its advanced joint replacement systems, shoulder solutions, and patient-specific surgical technologies.

Conformis, Inc. - Holds a 4.1% share, fueled by its customized, patient-specific knee and hip implants leveraging 3D-printing and AI-driven design.

DJO Global, Inc. - Holds a 3.4% share, supported by its orthopedic bracing, rehabilitation devices, and growing surgical solutions portfolio.

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Market Drivers

• Rising prevalence of osteoarthritis, rheumatoid arthritis, and joint degeneration increasing the demand for knee replacement procedures.

• Aging global population driving higher incidence of knee-related mobility issues and surgical interventions.

• Technological advancements such as robotic-assisted knee replacement, 3D-printed implants, and personalized prosthetics improving outcomes.

• Growing awareness and acceptance of minimally invasive orthopedic surgeries with shorter recovery times.

• Increasing obesity rates contributing to knee joint wear-and-tear and growing surgical demand.

• Expansion of orthopedic care centers and improved access to joint replacement services in emerging markets.

• Enhanced implant durability and design innovations driving long-term adoption of partial and total knee replacement procedures.

Industry Developments

• Introduction of next-generation robotic-assisted knee replacement systems enhancing precision and recovery outcomes.

• Development of custom, patient-specific implants using 3D printing and advanced imaging technologies.

• Expansion of cementless knee implant designs offering better long-term fixation and improved biocompatibility.

• Strategic partnerships between orthopedic device manufacturers and hospitals to expand surgical robotics programs.

• Increased investments in smart implants with embedded sensors for real-time monitoring of joint performance.

• Rise in outpatient knee replacement procedures supported by advancements in minimally invasive orthopedic techniques.

• Growing regulatory approvals for advanced knee implants and digital surgery platforms.

Regional Insights

North America - 42% share: "Driven by high osteoarthritis prevalence, strong adoption of robotic knee replacement systems, and advanced orthopedic care infrastructure."

Europe - 30% share: "Supported by growing demand for minimally invasive orthopedic surgeries, increasing elderly population, and rapid adoption of next-generation knee implants."

Asia Pacific - 20% share: "Fueled by rising medical tourism, expanding hospital infrastructure, increasing arthritis cases, and growing affordability of joint replacement procedures."

Latin America - 5% share: "Boosted by improving orthopedic care access, rising joint-related disorders, and growing adoption of affordable knee replacement solutions."

Middle East & Africa - 3% share: "Driven by increasing investments in specialty orthopedic centers, rising lifestyle-related joint issues, and gradual expansion of surgical capabilities."

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Key Segments

➥ By Procedure Type
Total Knee Replacement
A comprehensive surgical procedure involving complete resurfacing of the knee joint for patients with severe arthritis or joint degeneration.

Partial Knee Replacement
Minimally invasive procedure replacing only the damaged compartment of the knee, preserving healthy bone and ligaments for faster recovery.

Revision Knee Replacement
A corrective procedure performed to replace or repair failed or worn-out knee implants from previous surgeries, addressing complications or implant loosening.

➥ By Implant Type
Fixed-Bearing Implants
Traditional implants where the polyethylene insert is fixed to the tibial component, offering stability and long-term durability.

Mobile-Bearing Implants
Advanced implants designed to allow rotational movement between components, improving flexibility and reducing wear.

Medial Pivot Implants
Implants engineered to mimic the natural movement of the knee joint by providing a stable medial pivot point for improved biomechanics.

Customized Implants
Patient-specific implants created using imaging and 3D modeling to enhance fit, precision, and surgical outcomes.

➥ By Component
Femoral Component
The metal component attached to the end of the femur, designed to articulate smoothly with the tibial surface.

Tibial Component
Placed on top of the tibia, this component can be fixed-bearing or mobile-bearing and supports the polyethylene insert.

Patellar Component
A polyethylene button affixed to the back of the patella to facilitate smooth movement against the femoral component.

➥ By Fixation Type
Cemented Fixation
Uses bone cement to secure the implant components in place, offering immediate stability and widely used in elderly patients.

Cementless Fixation
Implants with porous surfaces allowing natural bone growth for long-term stability, ideal for younger or more active patients.

Hybrid Fixation
Combines cemented fixation for some components and cementless fixation for others, optimizing durability and bone integration.

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