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United States Treatment-Resistant Depression Market Trends and Forecast 2024-2031: Antipsychotics, SSRIs, SNRIs, and Novel Treatment Developments
Treatment-Resistant Depression Market
According to DataM Intelligence has published a new research report on "Treatment-Resistant Depression Market Size 2025". The report explores comprehensive and insightful Information about various key factors like Regional Growth, Segmentation, CAGR, Business Revenue Status of Top Key Players and Drivers. The purpose of this report is to provide a telescopic view of the current market size by value and volume, opportunities, and development status.
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➣ Recent Developments:
United States: Recent Developments - Treatment-Resistant Depression (TRD)
✅ August 2025 - The FDA approved a new esketamine nasal spray formulation with extended dosing intervals, improving patient adherence and outpatient management for TRD.
✅ July 2025 - Biotech companies launched AI-driven personalized therapy platforms integrating pharmacogenomic data to optimize antidepressant selection for TRD patients.
✅ June 2025 - Clinical trials for novel psychedelic-based therapies (psilocybin and MDMA derivatives) demonstrated rapid symptom reduction in patients unresponsive to conventional treatments.
Europe: Recent Developments - Treatment-Resistant Depression (TRD)
✅ August 2025 - Germany: European regulators approved deep brain stimulation (DBS) devices for severe TRD, providing targeted neuromodulation therapy.
✅ July 2025 - UK: NHS pilot programs integrated AI-based remote monitoring tools to track treatment response and optimize therapy adjustments for TRD patients.
✅ June 2025 - France: New clinical trials explored multi-modal combination therapies, pairing novel antidepressants with psychotherapy and neuromodulation to enhance efficacy.
➣ Top Industry Players:
Pfizer Inc., Viatris Inc., Novartis AG, AbbVie Inc., Eli Lilly and Company, Otsuka America Pharmaceutical, Inc., AstraZeneca, Camber Pharmaceuticals, Inc., Biodesix and Validus Pharmaceuticals LLC
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➣ Key Segments:
By Drugs: Antipsychotics (Aripiprazole (Abilify), Brexpiprazole (Rexulti), Quetiapine (Seroquel), Olanzapine (Zyprexa), Selective Serotonin Reuptake Inhibitors (SSRIs) (Fluoxetine (Prozac), Sertraline (Zoloft), Citalopram (Celexa), Paroxetine (Paxil), Serotonin and Noradrenaline Reuptake Inhibitors (SNRIs) (Duloxetine (Cymbalta), Venlafaxine (Effexor XR), Desvenlafaxine (Pristiq), Monoamine Oxidase Inhibitors (MAOIs) (Phenelzine (Nardil), Isocarboxazid (Marplan), Others
By Route of Administration: Oral, Injectable, Others
By Distribution Channel: Hospital Pharmacies, Retail Pharmacies, Online Pharmacies
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