Protein Detection & Quantification Market to Reach USD 5.13 Billion by 2031, Growing at 9.60% CAGR from 2024-2031 | Western Blotting Segment Leads as Specificity Demand Rises | DataM Intelligence

Leander, Texas and TOKYO, Japan - Nov. 14 2025 "The Protein Detection & Quantification Market was valued at US$ 2.25 billion in 2022 and is projected to reach approximately US$ 5.13 billion by 2031, growing at a CAGR of 9.60% during the forecast period 2024-2031."

The Protein Detection & Quantification Market is driven by growing demand for accurate protein analysis in drug development, disease diagnostics, and biomedical research. Market growth is supported by advancements in mass spectrometry, immunoassays, and fluorescence based techniques, along with increasing adoption of precision medicine and biomarker discovery initiatives.

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☛ Recent Industry Developments :
United States:
✅ November 2025: Thermo Fisher Scientific launched a new ultra sensitive fluorescence based protein quantification kit, enabling picogram level detection for oncology and biomarker research. The launch was supported by 110 million invested in advanced assay chemistry and U.S. production upgrades.

✅ October 2025: Bio Rad Laboratories completed the acquisition of a digital immunoassay startup, expanding its portfolio of next-generation protein detection platforms. The company allocated 78 million to integrate microfluidics technology and accelerate commercialization across research labs.

✅ September 2025: Agilent Technologies partnered with a leading U.S. biotech to launch a mass-spec-enhanced protein quantification workflow for high throughput proteomics. The collaboration included 52 million in joint R&D investment, targeting drug discovery and precision medicine applications.

Japan:
✅ November 2025: Shimadzu Corporation introduced a new LC-MS/MS protein quantification system with enhanced dynamic range for clinical proteomics. The rollout was backed by 38 million invested in instrument innovation and domestic manufacturing capacity.

✅ October 2025: Fujifilm Wako Chemicals acquired a Japanese biosensor company to strengthen its protein detection reagent line. The acquisition involved 44 million earmarked for expanding biosensor based quantification technologies for medical diagnostics.

✅ September 2025: Hitachi High Tech launched an automated immunoassay analyzer designed for precise low abundance protein detection in biomedical research. The development was supported by 26 million in R&D funding focused on automation and assay sensitivity improvement.

☛ Core Catalysts Behind Market Growth:
Increasing focus on biomarker discovery, disease diagnostics, and drug development is driving demand for advanced protein detection and quantification techniques.

Rising prevalence of chronic and infectious diseases is boosting the need for accurate protein analysis in clinical and research settings.

Technological advancements in mass spectrometry, immunoassays, and electrophoresis are enhancing sensitivity, accuracy, and throughput of protein quantification methods.

Growing investments in proteomics research, personalized medicine, and pharmaceutical R&D are further accelerating the adoption of innovative protein detection platforms.

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☛ Market Segmentation :
By Technology :
Western Blotting leads with 32% share, driven by its high specificity and reliability in protein separation, detection, and validation across research and diagnostics.

ELISA holds 28%, supported by widespread clinical use, high sensitivity, and suitability for large scale protein quantification.

Mass Spectrometry accounts for 18%, growing rapidly due to advancements in proteomics, biomarker discovery, and high throughput workflows.

Spectroscopy & Colorimetric Assays capture 14%, valued for their simplicity, cost effectiveness, and routine use in biochemical laboratories.

Other emerging technologies represent 8%, including microarrays, chromatography based systems, and label free detection platforms.

By Product :
Reagents dominate with 40% share, driven by recurring demand for antibodies, buffers, substrates, and assay kits across research institutions and clinical labs.

Instruments account for 27%, supported by growing adoption of advanced detection systems such as mass spectrometers, microplate readers, and blot analyzers.

Kits hold 23%, fueled by the need for standardized, ready-to-use solutions enabling reproducible quantification and high experimental efficiency.

Software & Services represent 10%, with increasing importance in data processing, workflow automation, and integration with proteomics platforms.

By Application :
Drug Discovery & Development leads with 33% share, driven by rising investment in biologics, target identification, and mechanism of action studies.

Clinical Diagnostics holds 26%, supported by increased use of protein biomarkers for disease detection, cancer diagnostics, and immunological testing.

Proteomics Research captures 22%, propelled by advancements in mass spectrometry, structural biology, and personalized medicine.

Agricultural & Environmental Testing accounts for 10%, used for protein level analysis in food safety, plant biology, and environmental monitoring.

Other applications represent 9%, including forensic science, industrial biotechnology, and academic studies.

By End-User :
Pharmaceutical & Biotechnology Companies dominate with 38% share, driven by rising R&D spending, biologics manufacturing, and therapeutic protein analysis.

Academic & Research Institutes hold 30%, as universities and labs increasingly study protein expression, interactions, and biomarker discovery.

Clinical Laboratories account for 22%, supported by demand for diagnostic assays and protein quantification in patient testing.

Others capture 10%, including CROs, food testing labs, environmental labs, and agricultural research centers.

☛ Competitive Landscape:
The market is characterized by strong competition among global life science companies, biotechnology solution providers, and analytical instrument manufacturers.

Thermo Fisher Scientific leads the global market with an estimated 24% share, driven by its extensive portfolio of protein assays, spectrophotometers, western blotting systems, and advanced mass spectrometry platforms. The company reported strong double-digit growth in 2024 across proteomics research solutions.

Danaher Corporation holds approximately 20% market share, supported by its subsidiaries such as Cytiva and Molecular Devices. The company continues expanding its protein analysis technologies through strategic acquisitions and R&D investments.

Bio Rad Laboratories, Inc. captures around 18% market share, maintaining a strong presence in protein gels, electrophoresis systems, immunoassays, and imaging platforms used across academic and industrial research labs.

Merck & Co., Inc. (Merck KGaA in life science segment) commands 16% of the market, driven by its high-performance chromatography systems, ELISA kits, and quantitative proteomics tools integrated into pharmaceutical and clinical workflows.

GE Healthcare holds close to 12% market share, driven by its strong portfolio in protein purification, labeling, and quantification technologies, particularly within biopharmaceutical manufacturing and high-throughput analytics.

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☛ Regional Analysis:
North America :
North America leads the market with 38%, supported by advanced research infrastructure, high R&D spending, and strong adoption of proteomics technologies in the U.S. and Canada. Growing applications in drug discovery, clinical diagnostics, and precision medicine drive significant regional demand.

Europe :
Europe holds 29%, driven by strong biotechnology and pharmaceutical sectors across Germany, the U.K., France, and Switzerland. Increasing funding for proteomics, biomarker discovery, and academic research institutions further accelerates adoption.

Asia Pacific :
Asia Pacific accounts for 23%, fueled by growing investments in genomics and proteomics research in China, Japan, India, and South Korea. Expanding biotech industries, rising prevalence of chronic diseases, and increasing diagnostic testing support market growth.

Latin America :
Latin America holds 5%, with demand concentrated in Brazil, Mexico, and Argentina. Expanding clinical research, growing adoption of molecular diagnostics, and increasing healthcare spending contribute to gradual market expansion.

Middle East :
The Middle East accounts for 3%, supported by advancements in healthcare systems in GCC countries and growing investments in diagnostic technologies. Rising focus on early disease detection boosts demand for protein quantification tools.

Africa :
Africa holds 2%, with usage mainly in South Africa and Egypt. Limited research funding and infrastructure constrain widespread adoption, though gradual improvements in diagnostic labs are driving slow but steady growth.

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