Acute Respiratory Distress Syndrome Pipeline Drugs Landscape Report 2025: MOA Analysis, R&D Progress, Clinical Trial Pipeline, and Strategic Market Evolution

DelveInsight's, "Acute Respiratory Distress Syndrome Pipeline Insights 2025" report provides comprehensive insights about 50+ companies and 50+ pipeline drugs in Acute Respiratory Distress Syndrome pipeline landscape. It covers the Acute Respiratory Distress Syndrome pipeline drug profiles, including clinical and nonclinical stage products. It also covers the Acute Respiratory Distress Syndrome therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

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Key Takeaways from the Acute Respiratory Distress Syndrome Pipeline Report

* On 21 November 2025, PPD Development LP conducted a Phase 2 study that will evaluate the safety and efficacy of host-directed therapeutics in hospitalized adults diagnosed with Acute Respiratory Distress Syndrome (ARDS) utilizing a platform trial design.
* On 17 November 2025, AstraZeneca initiated a Phase III study is to evaluate the effect of tozorakimab, as an add-on to SoC in patients with viral lung infection requiring supplemental oxygen, on the prevention of death or progression to IMV/ECMO.
* On 12 November 2025, Aerogen Pharma Limited announced a study comparing preterm subjects with RDS who are treated with APC-0101 and nCPAP/NIV to subjects treated with nCPAP/NIV alone (Sham). In Part 1, subjects will be followed until they reach 40 weeks post-menstrual age (PMA) or are discharged from the NICU, whichever comes first. In Part 2, subjects will undergo post-term follow-up through 12 months corrected age.
* DelveInsight's Acute Respiratory Distress Syndrome Pipeline report depicts a robust space with 50+ active players working to develop 50+ pipeline therapies for Acute Respiratory Distress Syndrome treatment.
* The leading Acute Respiratory Distress Syndrome Companies such as Staidson (Beijing) Biopharmaceuticals Co., Ltd, Cartesian Therapeutics, GEn1E Lifesciences, Aqualung Therapeutics Corp., Theratome Bio, Meridigen Biotech Co., Ltd., Dompe Farmaceutici S.p.A, Veru Healthcare, Windtree Therapeutics, MiNK Therapeutics, Avalo Therapeutics, Inc., Cynata Therapeutics Limited, Thiogenesis Therapeutics Inc., Arch Biopartners, Ibudilast , and others.
* Promising Acute Respiratory Distress Therapies such as STSA-1002, Rhu-pGSN, Reparixin 600mg, Centhaquine, MRG-001, TTI-0102, Dexamethasone , and others.

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The Acute Respiratory Distress Syndrome Pipeline Report provides disease overview, pipeline scenario and therapeutic assessment of the key pipeline therapies in this domain. The Acute Respiratory Distress Syndrome Pipeline Report also highlights the unmet needs with respect to the Acute Respiratory Distress Syndrome.

Acute Respiratory Distress Syndrome Overview

ARDS is a rapidly progressive disease occurring in critically ill patients. The major complication in ARDS is marked by leakage of fluid into the lungs, making breathing difficult or impossible. It is a severe lung condition that causes low blood oxygen. People who develop ARDS are usually ill due to another disease or a major injury which leads to fluid build-up inside the tiny air sacs of the lungs, and surfactant breakdown. The causes of ARDS are divided into two categories: direct or indirect injuries to the lung. Some of the direct injuries to the lung include pneumonia, aspiration, trauma, and others. Whereas the indirect injuries to the lung include inflammation of the pancreas, severe infection (also known as sepsis), blood transfusions, burns, and medication reactions.

Acute Respiratory Distress Syndrome Emerging Drugs Profile

* GEn 1124: GEn1E Lifesciences

GEn 1124 is an investigative small molecule drug being developed in collaboration with GEn1E Lifesciences and Biomedical Advanced Research and Development Authority (BARDA),part of the Administration for Strategic Preparedness and Response within the U.S. Department of Health and Human Services to support the development of the company's novel therapy for acute respiratory distress syndrome (ARDS), The drug candidate is mitogen activated protein kinase 14 inhibitors .Currently, the drug is in Phase II stage of its development for the treatment of acute respiratory distress syndrome.

* ALT-100: Aqualung Therapeutics Corp.

ALT-100 is a "First in Man" immune-based monoclonal antibody (mAb) being developed by Aqualung Therapeutics Corp. ALT-100 antibody is a revolutionary, next generation antibody therapy. The humanized antibody has been developed and optimized by Fusion Antibodies' revolutionary CDRx humanization and ADD develop ability platforms. This humanized monoclonal antibody will block systemic inflammation and will improve survival in the ARDS. ALT-100 inhibits eNAMPT binding to TLR4.Currently the drug is in Phase II stage of clinical trial for the treatment of acute distress respiratory syndrome.

* STSA 1002: Staidson (Beijing) Biopharmaceuticals Co., Ltd

STSA 1002 is an investigative recombinant anti-human C5a IgG1 monoclonal antibody which acts by targeting complement C5a inhibitors C5a by specifically binding to anaphylatoxin C5a, C5a loses its ability to bind to receptors and blocks C5a-induced Biological functions, such as neutrophil chemotaxis, degranulation and oxygen respiratory burst, etc., while not affecting C5 cleavage and the formation of membrane attack complex (MAC), retaining the bacteriolytic and bactericidal functions of the complement system, thereby achieving the treatment of viruses, etc. Severe pneumonia, acute lung injury or acute respiratory distress syndrome caused by factors. It is administered through oral and subcutaneous route. Currently, the drug is in Phase I/II stage of its development for the treatment of acute respiratory distress syndrome.

* Descartes 30: Cartesian Therapeutics

Descartes-30 is an off-the-shelf (allogeneic) MSC product engineered with Cartesian's RNA ArmorySM cell therapy platform. Descartes-30 expresses a unique combination of DNases in patients and delivers a targeted treatment directly to the site of disease which eliminates neutrophil extracellular traps which are a key driver of inflammation and clotting in acute respiratory distress syndrome. The drug candidate relies on cell replacements mechanism of action. Currently the drug is in Phase I/II stage of clinical trial for the treatment of acute respiratory distress syndrome.

The Acute Respiratory Distress Syndrome Pipeline report provides insights into

* The report provides detailed insights about companies that are developing therapies for the treatment of Acute Respiratory Distress Syndrome with aggregate therapies developed by each company for the same.
* It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Acute Respiratory Distress Syndrome Treatment.
* Acute Respiratory Distress Syndrome Companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
* Acute Respiratory Distress Syndrome Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.
* Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the Acute Respiratory Distress Syndrome market

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Acute Respiratory Distress Syndrome Companies

Staidson (Beijing) Biopharmaceuticals Co., Ltd, Cartesian Therapeutics, GEn1E Lifesciences, Aqualung Therapeutics Corp., Theratome Bio, Meridigen Biotech Co., Ltd., Dompe Farmaceutici S.p.A, Veru Healthcare, Windtree Therapeutics, MiNK Therapeutics, Avalo Therapeutics, Inc., Cynata Therapeutics Limited, Thiogenesis Therapeutics Inc., Arch Biopartners, Ibudilast, and others.

Acute Respiratory Distress Syndrome Pipeline Report provides the therapeutic assessment of the pipeline drugs by the Route of Administration

* Oral
* Parenteral
* Intravitreal
* Subretinal
* Topical

Acute Respiratory Distress Syndrome Products have been categorized under various Molecule types such as

* Monoclonal Antibody
* Peptides
* Polymer
* Small molecule
* Gene therapy

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Scope of the Acute Respiratory Distress Syndrome Pipeline Report

* Coverage- Global
* Acute Respiratory Distress Syndrome Companies- Staidson (Beijing) Biopharmaceuticals Co., Ltd, Cartesian Therapeutics, GEn1E Lifesciences, Aqualung Therapeutics Corp., Theratome Bio, Meridigen Biotech Co., Ltd., Dompe Farmaceutici S.p.A, Veru Healthcare, Windtree Therapeutics, MiNK Therapeutics, Avalo Therapeutics, Inc., Cynata Therapeutics Limited, Thiogenesis Therapeutics Inc., Arch Biopartners, Ibudilast , and others.
* Acute Respiratory Distress Therapies- STSA-1002, Rhu-pGSN, Reparixin 600mg, Centhaquine, MRG-001, TTI-0102, Dexamethasone , and others.
* Acute Respiratory Distress Syndrome Therapeutic Assessment by Product Type: Mono, Combination, Mono/Combination
* Acute Respiratory Distress Syndrome Therapeutic Assessment by Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III

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Table of Content

* Introduction
* Executive Summary
* Acute Respiratory Distress Syndrome: Overview
* Pipeline Therapeutics
* Therapeutic Assessment
* Acute Respiratory Distress Syndrome- DelveInsight's Analytical Perspective
* Late Stage Products (Phase III)
* Drug name: Company name
* Drug profiles in the detailed report.....
* Mid Stage Products (Phase II)
* GEn 1124: GEn1E Lifesciences
* Drug profiles in the detailed report.....
* Early Stage Products (Phase I/II)
* STSA 1002: Staidson (Beijing) Biopharmaceuticals Co., Ltd
* Drug profiles in the detailed report.....
* Preclinical and Discovery Stage Products
* Drug Name: Company Name
* Drug profiles in the detailed report.....
* Inactive Products
* Acute Respiratory Distress Syndrome Key Companies
* Acute Respiratory Distress Syndrome Key Products
* Acute Respiratory Distress Syndrome- Unmet Needs
* Acute Respiratory Distress Syndrome- Market Drivers and Barriers
* Acute Respiratory Distress Syndrome- Future Perspectives and Conclusion
* Acute Respiratory Distress Syndrome Analyst Views
* Acute Respiratory Distress Syndrome Key Companies

About Us

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