NGS-based RNA-seq Market Size, Growth Analysis 2032 by Key Vendors- Illumina, Thermo Fisher Scientific, Agilent Technologies, F. Hoffmann-La Roche, QIAGEN

USA, New Jersey: According to Verified Market Research analysis, the global NGS-based RNA-seq Market size was valued at USD 3.17 Billion in 2023 and is projected to reach USD 12.81 Billion by 2031, growing at a CAGR of 19.05% from 2024 to 2031.

How AI and Machine Learning Are Redefining the future of NGS-based RNA-seq Market?

AI and machine learning are revolutionizing the NGS-based RNA-seq Market by accelerating data interpretation, enhancing transcriptomic accuracy, and supporting advanced biomarker discovery. As researchers demand faster turnaround, predictive analytics and automation-driven workflows are becoming central to market penetration strategies, improving reproducibility across large-scale sequencing studies and multi-omics research environments.

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AI-driven alignment algorithms reduce noise, elevate read quality, and streamline transcript quantification for more reliable sequencing outcomes.

Machine learning models classify expression profiles, enabling high-resolution identification of disease-specific molecular signatures.

Automated pipelines accelerate differential gene expression analysis, minimizing human error and improving workflow efficiency in complex studies.

Predictive analytics support drug discovery by correlating RNA expression patterns with therapeutic response markers.

Smart solutions enhance single-cell RNA-seq interpretation, delivering deeper insights into cellular heterogeneity and immune profiling.

AI-enabled cloud platforms optimize data storage, security, and scalability while ensuring compliance with evolving regulatory shifts.

What are the top trends and innovations in the NGS-based RNA-seq Market to watch in 2025?

The NGS-based RNA-seq Market in 2025 is shaped by new sequencing chemistries, automation technologies, and multi-omics integrations that redefine molecular diagnostics and precision medicine. Growing investments in high-throughput platforms and advanced analytics are boosting global adoption, while digital transformation trends push laboratories to embrace interoperable, cloud-ready sequencing ecosystems.

Single-cell and spatial transcriptomics emerge as dominant trends, enabling high-resolution mapping of cellular architecture and gene expression dynamics.

Long-read RNA sequencing gains momentum, supporting full-length transcript characterization and improved isoform detection across complex genomes.

Automated sample prep systems reduce workflow bottlenecks, allowing labs to scale sequencing operations with improved consistency and throughput.

Cloud-native bioinformatics platforms expand accessibility to advanced analysis tools, enabling real-time collaborative research and secure data mobility.

Multi-omics integration accelerates systems biology research by combining RNA-seq with proteomics, epigenomics, and metabolomics datasets.

AI-powered sequencing instruments deliver real-time quality control and adaptive analysis, strengthening accuracy and reducing operational costs.

What are the Drivers, Restraints and Opportunities of NGS-based RNA-seq Market?

The NGS-based RNA-seq Market is driven by expanding applications in oncology, immunology, and precision medicine, supported by rapid technological advancements. Despite high operational costs and data-processing challenges, the sector presents strong opportunities for innovation through cloud adoption, automation, and AI-enabled transcriptomic analytics across research and clinical settings.

Key market drivers include rising demand for transcriptome profiling in disease research, biomarker discovery, and targeted therapy development.

Growing adoption of next-generation platforms promotes deeper sequencing insights, faster turnaround times, and more scalable workflows.

Major restraints involve complex data-processing requirements and limited bioinformatics expertise across emerging research markets.

High instrument costs and infrastructure limitations pose barriers for small laboratories and decentralized research facilities.

Opportunities arise from AI-powered analytic engines and cloud-native platforms that reduce computational burden and improve accessibility.

Increasing collaboration between sequencing vendors, pharma companies, and academic institutions expands innovation potential and global market reach.

Major companies

Illumina, Thermo Fisher Scientific, Agilent Technologies, F. Hoffmann-La Roche, QIAGEN, PerkinElmer, Pacific Biosciences of California, Oxford Nanopore Technologies, Novogene Co., BGI, Macrogen, GENEWIZ, Eurofins Genomics, Twist Bioscience Corporation, MGI Tech Co., Paragon Genomics, NanoString Technologies, Lexogen, and Singular Genomics Systems.

Trends

Global Market Expansion: As markets continue to globalize, numerous enterprises in the NGS-based RNA-seq sector are actively exploring opportunities in emerging markets. Leveraging their expertise and resources, these companies are strategically expanding their footprint and reaching out to new customer segments, thereby capitalizing on evolving market dynamics.

Sustainable Practices: There's a noticeable surge in prioritizing sustainability within the market, spurred by both consumer preferences and regulatory mandates. This shift is manifesting in heightened adoption of eco-friendly materials, implementation of energy-efficient processes, and proactive initiatives aimed at waste reduction.

Digital Transformation: The NGS-based RNA-seq market is swiftly embracing digital transformation, incorporating cutting-edge technologies like AI, IoT, and blockchain. This transition is significantly enhancing operational efficiency, fostering product innovation, and elevating customer experiences through personalization.

Health and Wellness: Consumers are placing a growing emphasis on health and wellness, catalyzing the introduction of functional and nutritious products in the NGS-based RNA-seq market. Additionally, there's a notable trend towards integrating health-focused attributes into existing offerings to meet evolving consumer expectations.

Key Segments Are Covered in Report

NGS-based RNA-seq Market, By Product & Service

Sample Preparation Products
Sequencing Platforms and Consumables
Sequencing Services
Data Analysis, Storage and Management

NGS-based RNA-seq Market, By Technology

Sequencing by Synthesis (SBS)
Ion Semiconductor Sequencing
Single-molecule Real-time Sequencing
Nanopore Sequencing

NGS-based RNA-seq Market, By Application

Expression Profiling Analysis
Small RNA Sequencing
De Novo Transcriptome Assembly
Variant Calling and Transcriptome Epigenetics

NGS-based RNA-seq Market, By End-User

Research and Academia
Hospitals and Clinics
Pharmaceutical and Biotechnology Companies
Others

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Barriers to Entry

Strong Brand Loyalty: Established brands enjoy strong customer loyalty and trust, making it difficult for new entrants to capture market share without substantial investment in brand building and marketing campaigns.

Economies of Scale: Existing players benefit from economies of scale, which enable them to lower production costs per unit and offer competitive pricing, posing a barrier for new entrants to achieve similar cost efficiencies.

High Capital Requirements: Entry into NGS-based RNA-seq Market requires substantial initial investment in manufacturing facilities, distribution networks, and marketing, making it challenging for new entrants to compete effectively.

Regulatory Hurdles: Compliance with NGS-based RNA-seq industry regulations and standards adds complexity and cost to market entry, especially for startups or smaller firms lacking resources to navigate regulatory requirements effectively.

Regional Analysis

North America (USA and Canada)
Europe (UK, Germany, France and rest of Europe)
Asia-Pacific (China, Japan, India, and Rest of Asia Pacific)
Latin America (Brazil, Mexico, and Rest of Latin America)
Middle East and Africa (GCC and Rest of the Middle East and Africa)

The report offers analysis on the following aspects:

(1) Market Penetration: Comprehensive information on the product portfolios of the top players in the NGS-based RNA-seq Market.

(2) Product Development/Innovation: Detailed insights on the upcoming technologies, R&D activities, and product launches in the NGS-based RNA-seq market.

(3) Competitive Assessment: In-depth assessment of the market strategies, geographic and business segments of the leading players in the market.

(4) Market Development: Comprehensive information about emerging markets. This report analyzes the market for various segments across geographies.

(5) Market Diversification: Exhaustive information about new products, untapped geographies, recent developments, and investments in the NGS-based RNA-seq Market.

Frequently Asked Questions (FAQ)

1. What are the present scale and future growth prospects of the NGS-based RNA-seq Market?
Answer: The NGS-based RNA-seq Market size was valued at USD 3.17 Billion in 2023 and is projected to reach USD 12.81 Billion by 2031, growing at a CAGR of 19.05% from 2024 to 2031.

2. What is the current state of the NGS-based RNA-seq market?
Answer: As of the latest data, the NGS-based RNA-seq market is experiencing growth, stability, and challenges.

3. Who are the key players in the NGS-based RNA-seq market?
Answer: Illumina, Thermo Fisher Scientific, Agilent Technologies, F. Hoffmann-La Roche, QIAGEN, PerkinElmer, Pacific Biosciences of California, Oxford Nanopore Technologies, Novogene Co., BGI, Macrogen, GENEWIZ, Eurofins Genomics, Twist Bioscience Corporation, MGI Tech Co., Paragon Genomics, NanoString Technologies, Lexogen, and Singular Genomics Systems. are the Prominent players in the NGS-based RNA-seq market, known for their notable characteristics and strengths.

4. What factors are driving the growth of the NGS-based RNA-seq market?
Answer: The growth of the NGS-based RNA-seq market can be attributed to factors such as key drivers technological advancements, increasing demand, and regulatory support.

5. Are there any challenges affecting the NGS-based RNA-seq market?
Answer: The NGS-based RNA-seq market's challenges include competition, regulatory hurdles, and economic factors.

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