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Rising Cases Of Peripheral Artery Disease Fueling The Growth Of The Market Due To Increasing Prevalence And Risk Factors Emerges as a Core Driver of the Intermittent Claudication Market in 2025

11-21-2025 07:24 AM CET | Health & Medicine

Press release from: The Business Research Company

Intermittent Claudication

Intermittent Claudication

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What Is the Expected CAGR for the Intermittent Claudication Market Through 2025?
Strong expansion has characterized the market for intermittent claudication recently, projecting a rise from $12.81 billion in 2024 to $13.51 billion the following year, reflecting a compound annual growth rate of 5.5%. This upward trajectory during the past period is linked to several factors, including the growing prevalence of peripheral artery disease, heightened public understanding of vascular conditions, an aging global population, better detection rates for the condition, and escalating spending on healare services.

What's the Projected Size of the Global Intermittent Claudication Market by 2029?
Projections indicate that the market addressing intermittent claudication is positioned for substantial expansion across the coming years, reaching an estimated $16.99 billion by 2029, fueled by a compound annual growth rate (CAGR) of 5.9%; this upward trajectory during the forecasting window is largely attributable to the escalating incidence rates of diabetes, the rising burden of obesity, the increased frequency of cardiovascular ailments, growing consumption of both alcohol and tobacco products, and expanded outlays on healare services, while key movements shaping this period encompass progress in diagnostic tools for PAD, the incorporation of wearable technology, the adoption of tailored medical treatments, a market transition favoring drug-eluting stents, and innovations emerging within stem cell treatments.Drivers 1:

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Top Growth Drivers in the Intermittent Claudication Industry: What's Accelerating the Market?
As the prevalence of peripheral artery disease (PAD), a circulatory ailment characterized by constricted arteries diminishing limb blood flow and resulting in discomfort, numbness, and further issues, continues to rise, this trend is anticipated to propel the expansion of the market addressing intermittent claudication.This escalation in PAD occurrences is linked to several contributing elements, including demographic shifts towards older populations, the high incidence of diabetes, tobacco use, elevated blood pressure, higher body mass indexes, and inactive living patterns.The mechanism by which PAD induces intermittent claudication involves inadequate oxygen supply to the leg musculature during physical exertion, manifesting as pain and cramping.Illustratively, data published in June 2023 by the American Heart Association Journals, a scholarly, freely accessible periodical from the United States, estimated that PAD impacts between 7 and 12 million individuals within the US alongside a worldwide patient base of 200 million people.Consequently, the documented surge in peripheral artery disease cases stands as a primary catalyst for the market growth associated with intermittent claudication treatments.

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What Trends Will Shape the Intermittent Claudication Market Through 2029 and Beyond?
Key market players addressing intermittent claudication are concentrating efforts on cutting-edge pharmaceutical approaches, notably RIPK1 inhibitors, with the overarching goal of optimizing therapeutic results for individuals afflicted with peripheral artery disease (PAD) exhibiting claudication symptoms, thereby striving to boost circulation, mitigate inflammatory processes, and impede the advancement of the condition. These RIPK1 inhibitors represent specialized pharmaceuticals designed to obstruct the kinase function of RIPK1, resulting in a decrease in both inflammation and regulated cell demise. Illustratively, in August of 2022, the US Food and Drug Administration (FDA) granted clearance for a Phase II clinical investigation involving GFH312, a novel therapeutic candidate for intermittent claudication (IC) associated with peripheral artery disease (PAD), developed by the Chinese biotechnology firm GenFleet. This particular trial, which will employ a randomized, double-blinded, placebo-controlled design, is slated to occur across fifteen distinct investigative sites, offering a robust evaluation framework for GFH312, a RIPK1 inhibitor which preliminary investigations in animal subjects demonstrated efficacy in curtailing the inflammatory cascade.

What Are the Main Segments in the Intermittent Claudication Market?
The intermittent claudicationmarket covered in this report is segmented -

1) By Type: Medication Therapies; Revascularization
2) By Route Of Administration: Parenteral Route; Oral Route; Other Routes Of Administration
3) By Application: Hospitals; Clinics; Home Healare; Other Applications
4) By Distribution Channel: Hospital Pharmacies; Retail Pharmacies; Online Pharmacies

Subsegments:

1) By Medication Therapies: Antiplatelet Agents; Vasodilators; Phosphodiesterase Inhibitors; Cilostazol; Pentoxifylline
2) By Revascularization: Angioplasty; Stenting; Bypass Surgery; Endarterectomy

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Which Top Companies are Driving Growth in the Intermittent Claudication Market?
Major companies operating in the intermittent claudication market are Pfizer Inc., Bristol Myers Squibb Company, AstraZeneca PLC, Novartis AG, GSK plc, Eli Lilly and Company, Merck KGaA, Teva Pharmaceutical, Otsuka Pharmaceutical Co. Ltd., Sanofi S.A., Bayer AG, Hikma Pharmaceuticals PLC, Dr. Reddy's Laboratories, Pipelinepharma, Pharmaoffer, Alkem Laboratories, LGM Pharma, Aastrid Life Sciences Pvt. Ltd., Manus Aktteva Biopharma LLP, Enomark Pharma, Pharmacompass.

Which Regions Will Dominate the Intermittent Claudication Market Through 2029?
North America was the largest region in the intermittent claudication market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the intermittent claudication market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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