Insulin-like Growth Factors Market Forecast Driven by Increasing Demand for Pediatric and Adult Growth Hormone Therapies

InsightAce Analytic Pvt. Ltd. announces the release of a market assessment report on the "Insulin-like Growth Factors Market"- By Type (Mechano Growth Factor, Somatomedin C, IGF 1), By End-user (Hospitals, Medical Centers), Industry Trends, and Global Forecasts, 2022-2035 And Segment Revenue and Forecast To 2031."

The Insulin-like Growth Factors Market is valued at US$ 275.1 Mn in 2023, and it is expected to reach US$ 406.1 Mn by 2031, with a CAGR of 5.13% during the forecast period of 2024-2031.

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Insulin-like growth factors (IGFs) are naturally occurring proteins that play a pivotal role in regulating cellular growth, differentiation, and tissue development across various organ systems. Structurally similar to insulin, the pancreatic hormone, IGFs exhibit insulin-like effects in select tissues, though their glucose-lowering activity is comparatively limited. The primary isoforms, IGF-1 and IGF-2, are essential for normal physiological growth and development. Unlike other growth factors, including epidermal growth factor, platelet-derived growth factor, and nerve growth factor, IGFs are distinguished by their well-characterized endocrine functions in humans.

IGFs are critical for proper growth during childhood and adolescence, supporting the development and maturation of bones and connective tissues. In addition to their developmental functions, IGFs play a significant role in muscle growth and regeneration by stimulating protein synthesis and promoting the proliferation of muscle cells, thereby enhancing recovery and physical performance. IGF-1, in particular, contributes to bone formation and the maintenance of bone density by facilitating new bone tissue growth, which is crucial for skeletal strength and the prevention of fractures and degenerative conditions such as osteoporosis.

List of Prominent Players in the Insulin-like Growth Factors Market
• Boehringer Ingelheim International GmbH
• Genervon Biopharmaceuticals LLC
• Ascendis Pharma
• Regulaxis SAS
• MedImmune, LLC
• Other Prominent Players

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Market Dynamics
Drivers:
The growth of the insulin-like growth factor (IGF) therapeutics market is primarily fueled by the increasing prevalence of chronic conditions, including diabetes, cancer, and growth hormone deficiencies. Due to their critical role in regulating cellular growth and metabolic processes, IGFs are witnessing expanding therapeutic applications across diverse medical domains.

Advancements in regenerative medicine and anti-aging interventions have further amplified the use of IGFs, as these factors are integral to promoting cell proliferation and tissue repair. Additionally, rising health awareness and evolving lifestyle trends emphasizing physical fitness, muscle development, and overall wellness are contributing to increased adoption of IGF-based therapies and supplements aimed at enhancing performance and general health.

Challenges:
Despite their therapeutic promise, the broader adoption of IGF-based interventions faces several obstacles. Safety concerns, particularly potential associations with elevated cancer risk and other adverse effects, present substantial regulatory and ethical challenges. Comprehensive long-term studies are required to establish efficacy and safety, thereby fostering clinical and consumer confidence. Moreover, the incomplete understanding of IGF signaling pathways and their complex interactions with other biological systems continues to limit the development of highly targeted and optimized formulations.

Regional Trends:
North America is projected to maintain a leading position in the global IGF therapeutics market, driven by an aging population and corresponding declines in endogenous growth factor levels. The region's well-established research infrastructure, comprising prominent academic institutions, biotechnology firms, and pharmaceutical companies, is facilitating innovation and accelerating the clinical translation of IGF-based solutions. Robust investment in regenerative health and age-related therapies, combined with a strong biomedical research ecosystem, positions North America as a central contributor to the sustained growth of the global IGF market.

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Recent Developments:
• In Aug 2021, Ascendis Pharma A/S, a biopharmaceutical company, today announced that the U.S. Food and Drug Administration (FDA) has approved SKYTROFA (lonapegsomatropin-tcgd) for the treatment of pediatric patients one year and older who weigh at least 11.5 kg (25.4 lb) and have growth failure due to inadequate secretion of endogenous growth hormone (GH). The company uses its novel TransCon technologies to potentially create new treatments that make a meaningful difference in patients' lives.
• In January 2024, Ascendis Pharma A/S, After reaching an exclusive distribution agreement with Danish business Ascendis Pharma A/S (NASDAQ: ASND), Specialized Therapeutics Asia Pte Ltd (ST), an independent biopharmaceutical company, has expanded its portfolio to include three novel endocrinology medicines. The agreement states that ST will market Ascendis Pharma's weekly injectable pediatric human growth hormone treatment, SKYTROFATM (lonapegsomatropin), YORVIPATHTM (palopegteriparatide), for hypoparathyroidism, and TransConTM CNP (navepegritide), an investigational treatment for achondroplasia.

Segmentation of Insulin-like Growth Factors Market.
Global Insulin-like Growth Factors Market, By Type
• Mechano Growth Factor
• Somatomedin C
• IGF 1
Global Insulin-like Growth Factors Market - By End-user
• Hospitals
• Medical Centers
Global Insulin-like Growth Factors Market - By Region
North America-
• The US
• Canada
• Mexico
Europe-
• Germany
• The UK
• France
• Italy
• Spain
• Rest of Europe
Asia-Pacific-
• China
• Japan
• India
• South Korea
• Southeast Asia
• Rest of Asia Pacific
Latin America-
• Brazil
• Argentina
• Rest of Latin America
Middle East & Africa-
• GCC Countries
• South Africa
• Rest of the Middle East and Africa

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This release was published on openPR.