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2025-2034 Protein Expression Market Evolution: Disruptions, Innovations, and Untapped Opportunities

11-20-2025 05:02 AM CET | Health & Medicine

Press release from: The Business Research Company

Protein Expression

Protein Expression

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What Is the Expected CAGR for the Protein Expression Market Through 2025?
The market encompassing protein expression has experienced swift expansion lately, projected to climb from its 2024 valuation of $3.58 billion to $3.97 billion by 2025, reflecting an impressive compound annual growth rate (CAGR) of 10.8%; this upward trajectory during the historical period stems from significant activity in scientific research, progress in biopharmaceutical creation, forward movement in biotechnology, the processes of drug discovery and development, and the expansion of the overall healthcare sector.

What's the Projected Size of the Global Protein Expression Market by 2029?
Anticipation surrounds the protein expression sector, projecting a swift expansion in the immediate future, with its market valuation poised to reach $6.52 billion by 2029, reflecting a sustained compound annual growth rate (CAGR) of 13.2%. This upward trajectory over the projection timeframe is primarily fueled by advancements in personalized medicine methodologies, the burgeoning biosimilars industry, increased efforts in drug repurposing initiatives, encouraging regulatory frameworks, and developments in precision agriculture. Key movements set to define this period involve the adoption of cell-free expression systems, the utilization of CRISPR-Cas9 technology for gene manipulation, the push towards environmentally sound bioprocessing methods, the expanding role of contract research and manufacturing organizations, and the deployment of multi-modal expression platforms.

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Top Growth Drivers in the Protein Expression Industry: What's Accelerating the Market?
The escalating need for biologic agents designed to combat diverse genetic ailments and long-standing health conditions stands as a primary impetus behind the advancements and commercial growth witnessed in the protein expression sector. Biologics represent pharmaceutical products derived from living entities or incorporating elements sourced from living systems, encompassing items like proteins, tissues, genetic material, allergens, cells, blood constituents, entire blood products, and vaccines. The broader adoption of these biologics (including therapeutic proteins and others) for treating persistent illnesses such as malignancies, heart-related issues, and inherited disorders is consequently boosting the need for specialized protein expression apparatus and machinery. To illustrate this point, data released by the World Health Organization, a United Nations specialized body headquartered in Switzerland, indicated that in September 2022, 41 million fatalities occurred annually worldwide, with a substantial 74 percent attributed to non-communicable diseases, or chronic conditions. Therefore, the growing requirement for biologics serves as a significant catalyst propelling the protein expression market forward.

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What Trends Will Shape the Protein Expression Market Through 2029 and Beyond?
Leading firms within the protein expression arena are concentrating efforts on launching advanced offerings, exemplified by the Visium CytAssist Gene and Protein Expression Assay, aiming to substantially boost their market earnings. These cutting-edge products signify the deployment of sophisticated methodologies intended to enhance how swiftly, precisely, and effectively protein expression is achieved. To illustrate this, 10x Genomics Inc., an American biotech entity, released the Visium CytAssist Gene and Protein Expression Assay in May of 2023, a tool designed to facilitate the examination of comparative protein expression profiles within human immunological systems. A distinctive feature of Visium is its morphology-centric methodology, which permits H&E staining to occur prior to any chemical processing of the tissue specimen. This capability allows for three-dimensional spatial investigation using the very same sample material, thereby permitting scientists to scrutinize tissue architecture on the identical slide utilized for more in-depth spatial multiomic investigations. By employing a sequencing-based detection system, the Visium CytAssist Gene and Protein Expression facilitates the synchronized acquisition of gene expression across the entire transcriptome alongside protein levels and histological assessment, all derived from one tissue section within a solitary experimental run.

What Are the Main Segments in the Protein Expression Market?
The protein expressionmarket covered in this report is segmented -

1) By Protein Expression: Yeast Expression; Mammalian Expression; Algae Expression; Insect Expression; Bacterial Expression; Cell-free Expression
2) By Product: Reagents; Competent Cells; Expression vectors; Services; Instruments
3) By Application: Therapeutic; Industrial; Research
4) By End Use: Pharmaceutical And Biotechnological Companies; Academic Research; Contract Research Organizations

Subsegments:
1) By Yeast Expression: Saccharomyces Cerevisiae; Pichia Pastoris; Kluyveromyces Lactis
2) By Mammalian Expression: Chinese Hamster ovary* (CHO) Cells; Human Embryonic Kidney (HEK) Cells; Vero Cells
3) By Algae Expression: Green Algae; Blue-green Algae (Cyanobacteria)
4) By Insect Expression: Sf9 Cells; Hi5 Cells
5) By Bacterial Expression: Escherichia Coli (E. coli); Bacillus Subtilis
6) By Cell-free Expression: Wheat germ Extract; Rabbit Reticulocyte Lysate

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Which Top Companies are Driving Growth in the Protein Expression Market?
Major companies operating in the protein expression market include Agilent Technologies Inc., Bio-Rad Laboratories Inc., Thermo Fisher Scientific Inc., New England Biolabs Inc., Promega Corporation, Qiagen NV, Takara Bio Inc., Merck KGaA, Genscript Biotech Corporation, Life Technologies Corporation, Sigma-Aldrich Corporation, Lucigen Corporation, Synthetic Genomics Inc., Becton, dic*kinson & Company, Lonza Group Ltd., Geneva Biotech LLC, Viva Biotech Holdings, Sengenics LLC, ARTES Biotechnology GmbH, Addgene Inc., Profacgen, ProteoGenix Inc., Peak Proteins Ltd., Domainex Ltd., Jena Bioscience GmbH, EMD Millipore Corporation, Oxford Expression Technologies Ltd., Creative Biolabs Inc., Abnova Taiwan Corp, Accelagen Inc.

Which Regions Will Dominate the Protein Expression Market Through 2029?
North America was the largest region in the protein expression market in 2024. Western Europe was the second largest region in the protein expression market. The regions covered in the protein expression market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa

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