Press release
United States Gastric Cancer Treatment Market: Oral Drugs for Home Care Growth By 2025-2033 | Top Most Keyplayers - Merck & Co., Inc., Eli Lilly and Company, Genentech USA, Inc., Pfizer Inc., Astellas Pharma Inc.
Gastric Cancer Treatment Market
Global Gastric Cancer Treatment Market size reached US$ 5.82 billion in 2024 and is expected to reach US$ 14.66 billion by 2033, growing at a CAGR of 10.9% during the forecast period 2025-2033.
According to DataM Intelligence Comprehensive Report has released its latest report on the "Gastric Cancer Treatment Market Size 2025," providing a detailed analysis of market trends, key growth drivers, competitive landscape, and regional insights. The report includes market size (value and volume), CAGR projections, and emerging opportunities that help businesses identify growth areas and build effective strategies. Backed by data-driven insights and future outlook, this study serves as a valuable resource for companies looking to stay competitive and capitalize on market potential.
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Latest M & A:
In March 2025, the FDA granted full approval to Keytruda (pembrolizumab, Merck) in combination with trastuzumab and chemotherapy for first-line HER2-positive, PD-L1 CPS ≥1, locally advanced/metastatic gastric or GEJ adenocarcinoma, based on KEYNOTE-811 trial results.
Novel therapies targeting CLDN18.2 (zolbetuximab/Vyloy, by Astellas Pharma) gained regulatory approvals in the U.S., EU, and Japan for advanced CLDN18.2-positive, HER2-negative cases; biomarker-driven treatment trends continue to expand.
Amgen's bemarituzumab (FGFR2b antibody) showed positive late-stage trial results, advancing biomarker-guided therapy pipeline and boosting M&A interest for FGFR2b assets.
The FDA granted fast track status to DPTX3186, a novel agent in development for gastric cancer, promising significant therapeutic impact and expedited clinical review (November 2025).
Biosimilars market expansion: In July 2024, Zydus Lifesciences received Mexican regulatory approval for Mamitra, a trastuzumab biosimilar indicated for breast and gastric cancer, underscoring growth in affordable biologics.
Immune-oncology and ADC combinations (Enhertu for HER2-positive, novel PD-1/CLDN18.2 combos) are driving durable response rates, with ongoing integration into national guidelines in Europe and Asia.
Industry M&A deals see major pharma acquiring early-stage GI and antibody-drug conjugate (ADC) pipelines to broaden portfolios for gastric, colorectal, and other GI malignancies.
Asia-Pacific remains the largest market due to high incidence rates, rapid adoption of innovative therapies, and strong government screening programs, especially in China, Japan, and South Korea.
Technology and R&D investments focus on minimally invasive surgery, advanced imaging, precision diagnostics, and integrating AI into biomarker testing for improved patient stratification and personalized care.
Industry Developments:
USA Developments
September 19, 2025: The FDA approved the subcutaneous (under the skin) formulation of pembrolizumab (Keytruda Qlex) for solid tumor indications, including gastric cancer. This new delivery method aims to offer greater convenience and accessibility for patients compared to traditional intravenous (IV) infusion.
Ongoing Trend (Jul-Sept 2025): The market saw a significant push toward earlier use of immunotherapy in combination regimens, following the full FDA approval (March 2025) of pembrolizumab with trastuzumab and chemotherapy for first-line HER2-positive, PD-L1 positive gastric cancer.
Japan Developments
Ongoing Trend (Jul-Sept 2025): The Japanese market continued to see the rapid adoption and expanded use of antibody-drug conjugates (ADCs), particularly trastuzumab deruxtecan (Enhertu), as a standard of care for advanced HER2-positive gastric cancer, driven by its high efficacy in later lines of therapy.
Ongoing Regulatory Pressure (Jul-Sept 2025): The MHLW maintained stringent cost-control measures, including annual NHI price revisions, which exerted downward pressure on the prices of established gastric cancer drugs, driving manufacturers to focus on innovative combinations and newer targeted therapies to secure premium pricing.
Major Key Player:
Merck & Co., Inc., Eli Lilly and Company, Genentech USA, Inc., Pfizer Inc., Astellas Pharma Inc., Bristol-Myers Squibb Company, Blueprint Medicines Corporation, Daiichi Sankyo, Inc., BeiGene, Ltd., Ipsen Biopharmaceuticals Inc., Taiho Oncology, Inc., and Deciphera Pharmaceuticals, LLC.
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Key Segments:
➥ By Cancer Type: Non-Cardia (Distal) Stomach Cancer, Proximal Stomach Cancer, Diffuse Stomach Cancer, Lymphomas, Gastrointestinal Stromal Tumors, Carcinoid Tumors, Adenocarcinoma, Others
➥ By Treatment Type: Chemotherapy, Radiation Therapy, Targeted Therapy, Immunotherapy, Surgery, Others
➥ By Route of Administration: Injectable, Oral
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