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Top Market Shifts Transforming the CRISPR Gene Editing Market Landscape: Key Insights

11-19-2025 06:01 AM CET | Health & Medicine

Press release from: The Business Research Company

CRISPR Gene Editing

CRISPR Gene Editing

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What Is the Expected CAGR for the CRISPR Gene Editing Market Through 2025?
The market encompassing CRISPR gene editing has seen rapid, expansive growth over the last few years, projected to expand its value from $2.26 billion in 2024 to $2.88 billion the following year, reflecting a substantial compound annual growth rate (CAGR) of 27.1%; this historical expansion is fundamentally driven by several factors: a heightened requirement for genome modification techniques, augmented financial support from governmental bodies, the rising incidence of various cancers, the increasing spread of long-term ailments, greater public understanding regarding CRISPR methodologies, and improvements in the provision of healthcare facilities.

What's the Projected Size of the Global CRISPR Gene Editing Market by 2029?
Anticipated over the coming years is substantial expansion for the CRISPR gene editing market, projected to achieve a value of $6.99 billion by 2029, reflecting a compound annual growth rate (CAGR) of 24.9%. This projected surge across the forecast timeline stems from several key factors: the escalating incidence of inherited diseases, a heightened focus on personalized medical treatments, augmented capital flowing into CRISPR research and development initiatives, an aging global demographic, and the increasing adoption of gene therapy techniques. Within this same forecast timeframe, significant trends shaping the landscape involve technological progress in gene editing capabilities, a greater volume of ongoing research projects, developments in pharmaceutical creation and refinement, novel approaches being introduced for delivery systems, and the growing incorporation of CRISPR modifications within agricultural practices.

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Top Growth Drivers in the CRISPR Gene Editing Industry: What's Accelerating the Market?
The rising incidence of conditions rooted in genomic anomalies-spanning issues from single-gene defects to complex multi-gene or chromosomal irregularities-is anticipated to fuel the expansion of the CRISPR gene editing sector.This surge in genetic ailments stems from accumulated mutations, the aging of global demographics, and the practice of consanguinity.CRISPR technology offers a powerful solution for addressing these health challenges, enabling highly accurate, directed alterations within the DNA sequence.Researchers are leveraging CRISPR not only to pinpoint and rectify the exact faulty DNA segments responsible for these disorders but also to reinstate typical cellular function and mitigate the resulting clinical manifestations, as exemplified by ongoing work in sickle cell anemia and cystic fibrosis.To illustrate this trend, data released in July 2022 by the US non-profit Cystic Fibrosis Foundation highlighted a growing patient pool: roughly 40,000 individuals in the States and over 105,000 globally were living with CF that year.Consequently, this escalating burden of genetic disorders acts as a primary catalyst propelling the CRISPR gene editing market forward.

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What Trends Will Shape the CRISPR Gene Editing Market Through 2029 and Beyond?
Leading entities within the sphere of CRISPR gene editing are concentrating their efforts on pioneering novel offerings, notably gene therapy, with the objective of capturing broader consumer segments, boosting transactional volumes, and augmenting financial returns. Gene therapy constitutes a therapeutic methodology wherein genetic material is employed for addressing, forestalling, or remedying various ailments and dysfunctions. A notable illustration occurred in December 2023 when the Casgevy cell-based gene therapy secured authorization from the US Food and Drug Administration, an agency of the United States federal government, specifically for managing sickle cell disease; this Casgevy treatment leverages the CRISPR/Cas9 genome editing platform for adjusting hematopoietic stem cells.

What Are the Main Segments in the CRISPR Gene Editing Market?
The crispr gene editingmarket covered in this report is segmented -

1) By Type: CRISPR-Associated Nuclease (Cas Nuclease); Guide Ribonucleic Acid (RNA); Deoxyribonucleic Acid (DNA) Ligase; Restriction Endonuclease; Other Types
2) By Services: Design Tools; Plasmid And Vector; CRISPR-Associated Protein 9 (Cas9) And Guide Ribonucleic Acid (g-RNA); Delivery System Products; Other Services
3) By Technology: CRISPR Or Cas9; Zinc Finger Nucleases; Other Technologies
4) By Application: Agricultural; Biomedical; Industrial; Genome Engineering; Disease Models; Functional Genomics; Other Applications
5) By End User: Academic Institutes And Research Centers; Biotechnology Companies; Contract Research Organizations (CROs); Pharmaceutical And Biopharmaceutical Companies

Subsegments:
1) By CRISPR-Associated Nuclease (Cas Nuclease): Cas9; Cas12; Cas13; Other Cas Nucleases
2) By Guide Ribonucleic Acid (RNA): Single-guide RNA (sgRNA); Dual-guide RNA; Synthetic Guide RNA
3) By Deoxyribonucleic Acid (DNA) Ligase: T4 DNA Ligase; E. coli DNA Ligase; Other DNA Ligases
4) By Restriction Endonuclease: Type II Restriction Enzymes; Type I And III Restriction Enzymes; Other Restriction Enzymes
5) By Other Types: CRISPR Delivery Systems; CRISPR Plasmids; CRISPR-Based Diagnostic Tools

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Which Top Companies are Driving Growth in the CRISPR Gene Editing Market?
Major companies operating in the CRISPR gene editing market are Thermo Fisher Scientific Inc., Merck KGaA, Agilent Technologies Inc., GenScript, Integrated DNA Technologies Inc., Takara Bio Inc., OriGene Technologies Inc., Intellia Therapeutics Inc., New England Biolabs, Synthego, Arbor Biotechnologies Inc., Rockland Immunochemicals Inc., Cellectis, Editas Medicine, Caribou Biosciences Inc., System Biosciences LLC, Applied StemCell, Addgene, Mirus Bio LLC, Excision BioTherapeutics Inc., GeneCopoeia Inc., ToolGen Inc., Cellecta Inc., CRISPR Therapeutics, ERS Genomics Limited

Which Regions Will Dominate the CRISPR Gene Editing Market Through 2029?
North America was the largest region in the CRISPR gene editing market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the CRISPR gene editing market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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