Press release
Global Spasticity Treatment Landscape Set for Transformation: DelveInsight Unveils Insights into 12+ Pipeline Therapies
Spasticity Pipeline
Stay informed with the latest developments! Access DelveInsight's comprehensive Spasticity Pipeline Report to review emerging therapies, leading companies, and the evolving treatment landscape. Explore the report here - Spasticity Pipeline Outlook: https://www.delveinsight.com/sample-request/spasticity-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=apr
Key Insights from the Spasticity Pipeline Report
• July 2025: Celgene launched a Phase II study evaluating the safety, efficacy, and tolerability of three oral doses of BMS-986368―a dual FAAH/MAGL inhibitor―for managing Spasticity in patients with Multiple Sclerosis (BALANCE-MSS-1).
• June 2025: Ipsen initiated a study assessing escalating doses of IPN10200 to determine its pharmacodynamic profile and identify the optimal dose with the best balance of efficacy and safety for treating adult upper limb spasticity.
• The report outlines a dynamic pipeline with 10+ active companies developing 12+ novel therapeutic candidates targeting Spasticity.
• Major industry players include Elpida Therapeutics SPC, Saol Therapeutics, Revance Therapeutics Inc., BlackfinBio Ltd., Ipsen, Motor Pharma, Lundbeck A/S, and others.
• Notable emerging candidates include IPN10200, SL-1002, Botulinum toxin type A, SPARC0921, Tizanidine, Moxifloxacin, and Meditoxin® administered under ultrasonography guidance.
Discover advancements reshaping Spasticity care. Access the full clinical pipeline and study insights: https://www.delveinsight.com/sample-request/spasticity-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=apr
Spasticity Overview
Spasticity is a motor disorder characterized by increased muscle tone, stiffness, and involuntary spasms resulting from disrupted communication between the brain, spinal cord, and muscles. It commonly arises from neurological conditions such as stroke, multiple sclerosis, cerebral palsy, traumatic brain injury, and spinal cord injury. This abnormal muscle tightness can interfere with mobility, daily activities, and overall quality of life. Severity varies widely, ranging from mild tightness to painful, uncontrollable contractions. Management typically involves physical therapy, oral medications, botulinum toxin injections, or advanced interventions such as intrathecal therapies. Ongoing research aims to develop more targeted and long-lasting treatment options.
Emerging Spasticity Drug Profiles
MELPIDA - Elpida Therapeutics SPC
Elpida Therapeutics SPC, a Social Purpose Corporation, focuses on gene therapies for ultra-rare pediatric disorders. Its flagship candidate, Melpida, is an AAV9-mediated gene therapy engineered to deliver a functional AP4M1 gene for treating SPG50 via intrathecal administration. Having completed Phase I/II studies, it has received FDA clearance to progress to a Phase III trial involving eight children beginning August 2024. Beyond SPG50, Elpida is advancing gene therapy programs for conditions such as CMT4J. Melpida is currently in Phase III development.
SL-1002 - Saol Therapeutics
SL-1002 is a proprietary chemoneurolytic injection under evaluation for managing limb spasticity and knee osteoarthritis-related pain in adults. The therapy is currently in Phase II clinical development for Spasticity.
IPN-10200 - Ipsen
IPN-10200 is a next-generation, extended-duration botulinum neurotoxin type A (mrBoNT/A) developed to offer longer-lasting therapeutic effects. Administered intramuscularly, it is in Phase I/II clinical trials for both aesthetic indications (e.g., glabellar and forehead lines) and adult upper limb spasticity due to stroke or traumatic brain injury. Ongoing trials aim to determine its safety profile, efficacy, and optimal dosing regimen.
What the Spasticity Pipeline Report Covers
• Comprehensive profiles of companies developing Spasticity therapies and the total number of programs under each.
• Classification of therapeutic candidates by development stage: early-, mid-, and late-stage.
• Overview of active and inactive (paused or discontinued) development programs.
• Assessment of therapies by development phase, route of administration, mechanism of action, molecular type, and monotherapy vs. combination therapy.
• Detailed insights into ongoing collaborations, licensing agreements, and financial activities influencing pipeline progress.
Gain deeper visibility into groundbreaking programs advancing Spasticity treatment.
Explore the full report - Spasticity Unmet Needs: https://www.delveinsight.com/sample-request/spasticity-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=apr
Leading Companies in the Spasticity Pipeline
Elpida Therapeutics SPC | Saol Therapeutics | Revance Therapeutics Inc. | BlackfinBio Ltd | Ipsen | Motor Pharma | Lundbeck A/S | Others
Spasticity Pipeline Segmentation by Route of Administration
• Intravenous
• Subcutaneous
• Oral
• Intramuscular
Spasticity Pipeline Segmentation by Molecule Type
• Monoclonal antibody
• Small molecule
• Peptide
Access strategic insights into emerging therapies and key developmental milestones. Explore Spasticity Market Drivers, Barriers, and Forecasts:
https://www.delveinsight.com/sample-request/spasticity-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=apr
Scope of the Spasticity Pipeline Report
• Geographical Coverage: Global
• Key Companies: Elpida Therapeutics SPC, Saol Therapeutics, Revance Therapeutics Inc., BlackfinBio Ltd, Ipsen, Motor Pharma, Lundbeck A/S, and others
• Notable Pipeline Candidates: IPN10200, SL-1002, Botulinum toxin type A, SPARC0921, Tizanidine, Moxifloxacin, Meditoxin® (ultrasound-guided), etc.
• Therapeutic Assessment: Mono, Combination, and Hybrid regimens
• Development Stages: Discovery, Preclinical, Phase I, Phase II, Phase III
Identify the key innovators and leading programs in Spasticity drug development.
Explore the emerging drugs and major companies shaping the future:
https://www.delveinsight.com/sample-request/spasticity-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=apr
Contact Us:
Ankit Nigam
Manager Marketing
info@delveinsight.com
+14699457679
About DelveInsight
DelveInsight is a leading Life Science market research and business consulting company recognized for its off-the-shelf syndicated market research reports and customized solutions to firms in the healthcare sector.
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