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Global Nontuberculous Mycobacterial Infection Market Growth Accelerates: Strategic Forecast Predicts $19.37 Billion by 2029

11-18-2025 08:44 AM CET | Health & Medicine

Press release from: The Business Research Company

Nontuberculous Mycobacterial Infection

Nontuberculous Mycobacterial Infection

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What Will the Nontuberculous Mycobacterial Infection Industry Market Size Be by 2025?
The market valuation for nontuberculous mycobacterial infections is on an upward trajectory, moving from a total of $14.25 billion assessed in 2024 to an anticipated $14.96 billion the following year, reflecting a steady compound annual growth rate of 5.0%. This expansion observed during the preceding years has been fueled by advancements in detection methods, an increasing demographic of older individuals, heightened recognition of cystic fibrosis, and the wider use of immunosuppressive pharmaceuticals.

What's the Long-Term Growth Forecast for the Nontuberculous Mycobacterial Infection Market Size Through 2029?
Projections indicate robust expansion within the market addressing nontuberculous mycobacterial infections over the forthcoming period, estimated to reach a valuation of $19.37 billion by the year 2029, driven by a compound annual growth rate (CAGR) of 6.7%; this forward momentum is fundamentally supported by several factors, notably the ongoing development of antimicrobial pharmaceuticals, heightened public and clinical awareness concerning NTM, progress in genetic studies, and the increasing adoption of telehealth and remote patient oversight solutions, while the prevailing shifts shaping this landscape involve the movement toward individualized treatment protocols, amplified regulatory scrutiny, the utilization of combination therapeutic approaches, and the integration of novel digital health instruments.

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What Are the Key Growth Drivers Fueling the Nontuberculous Mycobacterial Infection Market Expansion?
The increasing worldwide incidence of chronic obstructive pulmonary disease (COPD) is projected to be a key element fueling the expansion of the market for nontuberculous mycobacterial infections. COPD, defined as a persistent and often worsening restriction of airflow in the lungs, creates conditions conducive to these infections; specifically, NTM infections in individuals suffering from COPD correlate with a more pronounced reduction in FEV1 values and a higher frequency of disease exacerbations. This underlying respiratory ailment can compromise immunological defenses and cause structural deterioration in lung tissue, thus lowering the barrier for NTM bacteria to establish an infection within the pulmonary system. Illustratively, data released in March 2023 by ScotPHO, a public health organization in Scotland, indicated an uptrend in COPD figures spanning 2021 to 2022; during this period, the rate for males rose from 83.2 to 97.6 cases per 100,000 individuals, and concurrently, the rate for females escalated from 72.6 to 97.3 per 100,000 people, underscoring why the escalating spread of COPD acts as a catalyst for the nontuberculous mycobacterial infection market's advancement.

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What Are the Key Trends Driving Nontuberculous Mycobacterial Infection Market Growth?
Leading corporations within the nontuberculous mycobacterial infection sector are implementing novel strategies like securing fast track designation for drug authorization to maintain their competitive standing. The FDA's Fast Track status represents a mechanism intended to accelerate both the creation and evaluation of pharmaceuticals targeting severe ailments where current medical solutions are inadequate. To illustrate this, the United States federal regulatory body, the Food and Drug Administration, conferred Fast Track Designation in July 2022 upon NUZYRA for managing lung disease caused by Mycobacterium avium complex (MAC) in nontuberculous mycobacteria patients. NUZYRA, which is omadacycline, functions as a cutting-edge, broad-spectrum antibacterial agent engineered to fight serious bacterial infections, inclusive of those stemming from resistant microbial strains. This bestowed status streamlines the necessary development timeline and the subsequent review procedures for the NUZYRA antibiotic, thereby addressing critical gaps in current medical care.

How Is the Nontuberculous Mycobacterial Infection Market Segmented?
The nontuberculous mycobacterial infectionmarket covered in this report is segmented -

1) By Drug Class: Macrolides; Rifampin; Aminoglycoside; Other Drug Classes
2) By Route Of Administration: Oral; Parenteral; Other Routes
3) By Distribution Channel: Hospital Pharmacies; Retail Pharmacies; Online Pharmacies

Subsegments:
1) By Macrolides: Azithromycin; Clarithromycin
2) By Rifampin: Rifampin; Rifabutin
3) By Aminoglycoside: Amikacin; Streptomycin
4) By Other Drug Classes: Ethambutol; Clofazimine; Linezolid

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Which Companies Are Leading the Charge in Nontuberculous Mycobacterial Infection Market Innovation?
Major companies operating in the nontuberculous mycobacterial infection market are Pfizer Inc., Johnson & Johnson, F. Hoffman La Roche AG, Merck & Co. Inc., AbbVie Inc., Bayer AG, Novartis AG, Sanofi S.A., Bristol Myers Squibb, AstraZeneca PLC, Abbott Laboratories, GlaxoSmithKline PLC, Takeda Pharmaceutical Company, Eli Lilly and Company, C.H. Boehringer Sohn AG & Co. KG, Teva Pharmaceutical Industries Ltd., Mylan N.V., Astellas Pharma Inc., Vertex Pharmaceuticals Inc., Sun Pharmaceutical Industries Ltd., Horizon Therapeutics PLC, Lupin Limited, BioMarin Pharmaceutical Inc., Ionis Pharmaceuticals Inc., Insmed Incorporated, Paratek Pharmaceuticals Inc., Spero Therapeutics Inc., Aradigm Corporation, Dauntless Pharmaceuticals Inc., Validus Pharmaceuticals LLC.

Which Regions Are Leading the Global Nontuberculous Mycobacterial Infection Market in Revenue?
North America was the largest region in the nontuberculous mycobacterial infection market in 2024. North America is expected to be the fastest-growing region in the forecast period. The regions covered in nontuberculous mycobacterial infection market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.

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