Press release
Future of the Global Primary Biliary Cholangitis Market: Trends, Innovations, and Key Forecasts Through 2034
Primary Biliary Cholangitis
Primary Biliary Cholangitis Market Size Growth Forecast: What to Expect by 2025?
The market valuation for primary biliary cholangitis has exhibited robust expansion lately, projected to escalate from $0.98 billion in 2024 to $1.06 billion by 2025, reflecting a compound annual growth rate averaging 7.9% over that timeframe; this historical upswing is underpinned by several key factors, including elevated consciousness surrounding the ailment, amplified worldwide spending on medical care, concerted alliances within the health industry, dedicated efforts toward supporting patient causes, and governmental programs aimed at promoting liver wellness.
How Will the Primary Biliary Cholangitis Market Size Evolve and Grow by 2029?
Anticipation suggests a robust escalation in the scale of the primary biliary cholangitis market across the ensuing years, projected to reach a value of $1.47 billion by 2029, propelled by a compound annual growth rate (CAGR) of 8.6 percent; this upward trajectory is fueled by several factors including the furtherance of biomarker investigations, worldwide initiatives concerning the handling of uncommon ailments, heightened partnership within studies, a shift toward care models centered on the patient, and the increasing need for liver transplant procedures. Key developments shaping this period encompass strides made in biomarker discovery, greater attention given to diagnostic methods that do not require invasive procedures, scientific concentration on therapies that modulate immune responses, the incorporation of artificial intelligence (AI) into processes, the inclusion of patient-validated results in clinical assessments, the utilization of remote consultation for managing patient care, a strategic leaning toward multi-drug treatments, and the development of novel treatments aimed at mitigating fibrosis.
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What Drivers Are Propelling the Growth of Primary Biliary Cholangitis Market Forward?
Anticipated escalation in tobacco use is projected to be a significant catalyst for the expansion of the primary biliary cholangitis market in the coming period; this habit involves drawing in and expelling smoke generated from combusted tobacco products or similar materials, representing a recognized contributor to liver ailments such as PBC, consequently meaning elevated prevalence of smoking will necessitate greater medical intervention for hepatic complications, for example, Statistics Canada reported in July 2023 that cigarette output across Canada climbed by 2.2% over the previous month, June 2023, further highlighting this trend, cigarette transactions saw a 2.6% jump in June, totaling 1.4 billion units relative to May figures, thereby indicating that heightened smoking activity will fuel the trajectory of the primary biliary cholangitis market.
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Which Emerging Trends Are Transforming the Primary Biliary Cholangitis Market in 2025?
Firms active within the primary biliary cholangitis domain are channeling efforts toward creating novel, highly specific therapies, including orphan medications that pair obeticholic acid (OCA) alongside bezafibrate for addressing primary biliary cholangitis (PBC), with the goal of securing exclusive market positioning. This blending of OCA and bezafibrate, coupled with orphan drug status, intends to provide a more thorough and potent strategy for handling PBC management, possibly elevating the standard of living for those afflicted with this uncommon ailment. To illustrate, in May 2023, the US pharmaceutical entity Intercept Pharmaceuticals, Inc. was granted orphan drug designation by the FDA for this combination, which acts as a PPAR agonist, as a prospective therapy for primary biliary cholangitis (PBC), a chronic liver disorder; moreover, obeticholic acid, commercialized under the name Ocaliva, already holds approval for PBC within the United States.
What Are the Key Segments in the Primary Biliary Cholangitis Market?
The primary biliary cholangitismarket covered in this report is segmented -
1) By Treatment Type: Drugs; Liver Transplantation
2) By Diagnosis: Imaging Tests; Magnetic Resonance Elastography (MRE); Magnetic Resonance Cholangiopancreatography (MRCP); Ultrasound; Fibroscan; Blood Tests; Cholesterol Test; Antibody Tests; Liver Tests; Other Diagnoses
3) By End-Users: Specialty Clinics; Homecare; Other End-Users
Subsegments:
1) By Drugs: Ursodeoxycholic Acid (UDCA); Obeticholic Acid (OCA); Fibrates; Immunosuppressive Drugs; Other Targeted Therapies
2) By Liver Transplantation: Orthotopic Liver Transplantation (OLT); Living Donor Liver Transplantation; Hepatobiliary Surgery For Liver Transplant
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Who Are the Key Players Shaping the Primary Biliary Cholangitis Market's Competitive Landscape?
Major companies operating in the primary biliary cholangitis market report are Pfizer Inc., F. Hoffmann-La Roche Ltd., Merck And Co. Inc., Novartis AG, Bristol-Myers Squibb Company, AstraZeneca PLC, GlaxoSmithKline PLC, Takeda Pharmaceutical Company, Amgen Inc., Boehringer Ingelheim International GmbH., Gilead Sciences Inc., Vertex Pharmaceuticals, Dr. Reddy's Laboratories Ltd., Amneal Pharmaceuticals LLC, Alnylam Pharmaceuticals Inc., Ionis Pharmaceuticals Inc., Intercept Pharmaceuticals Inc., Arrowhead Pharmaceuticals Inc., CureVac N.V., Sangamo Therapeutics Inc., Calliditas Therapeutics AB, NGM Biopharmaceuticals Inc., Bluebird Bio Inc., Intellia Therapeutics Inc., Albireo Pharma Inc., TARGET PharmaSolutions Inc., Genfit S.A., Editas Medicine Inc., CymaBay Therapeutics Inc., Ascletis Pharma Inc.
What Geographic Markets Are Powering Growth in the Primary Biliary Cholangitis Market?
North America was the largest region in the primary biliary cholangitis market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the primary biliary cholangitis market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
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