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Global Preclinical CRO Market Projected to Grow at 9.5% CAGR, Reaching $8.99 Billion by 2029

11-17-2025 09:57 AM CET | Health & Medicine

Press release from: The Business Research Company

Preclinical CRO

Preclinical CRO

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What Will the Preclinical CRO Industry Market Size Be by 2025?
The overall valuation of the preclinical CRO sector has experienced robust expansion lately, projected to advance from $5.7 billion in 2024 to reach $6.25 billion a year later, representing a 9.7% compound annual growth rate; this historical upward trajectory is fundamentally linked to the increasing necessity for accelerated pharmaceutical development timelines, the execution of cost-saving measures, a concentrated effort on primary business capabilities, the need to adhere to regulatory mandates, and the worldwide expansion characterizing clinical testing operations.

What's the Long-Term Growth Forecast for the Preclinical CRO Market Size Through 2029?
Anticipation is high for substantial expansion within the preclinical contract research organization (CRO) market over the forthcoming years, projecting a valuation of $8.99 billion by 2029, spurred by a consistent compound annual growth rate (CAGR) of 9.5%. This projected surge in expansion throughout the forecast window is fundamentally linked to several key factors: the growing adoption of personalized medicine approaches, heightened attention directed towards both rare diseases and orphan drugs, an upswing in outsourcing activities across the biopharmaceutical sector, greater emphasis placed on biomarker investigation, and the increasing necessity for generating real-world evidence. Furthermore, the key dynamics shaping this period encompass the incorporation of artificial intelligence (AI) capabilities, the widening scope of oncology studies, technological progress in omics platforms, improvements in both in vitro and in vivo modeling systems, and strengthened partnerships facilitating translational research efforts.

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What Are the Key Growth Drivers Fueling the Preclinical CRO Market Expansion?
Anticipated expansion in the need for studies conducted prior to human testing is set to fuel the forward trajectory of the preclinical CRO sector. These preliminary assessments involve all evaluations of a therapeutic agent or intervention performed before subjects in human trials are utilized. Such foundational investigations frequently encompass innovative medical apparatus, pharmaceutical products requiring prescriptions, and diagnostic tools; their principal aims revolve around determining a foundational, safe dosage suitable for initial human investigations and assessing any inherent harmful effects of the compound. Preclinical stages are absolutely vital in the process of bringing a drug to market, and their significance is mounting alongside a stronger focus on both the safety profile and the effectiveness of novel pharmaceuticals. Illustratively, data from IQVIA, an American firm specializing in the integration of healthcare data and clinical research services, indicated this February 2024 that productivity within clinical development saw an upturn throughout 2023, marked by the introduction of 69 novel active substances worldwide that year, representing an increase of six over the preceding year, which notably included 24 introductions that were pioneers in their class within the United States. Consequently, the surging requirement for services supporting these trials preceding human testing is actively pushing the expansion of the preclinical contract research organization market.

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What Are the Key Trends Driving Preclinical CRO Market Growth?
A significant trend propelling the preclinical CRO market forward revolves around the integration of technological progress. Market leaders within this sector are actively implementing novel technologies as a strategy to maintain or enhance their competitive standing. As an illustration, in February of 2023, BenchSci, a Canadian firm specializing in AI solutions for preclinical research and development, introduced ASCEND, which is an all-inclusive Software as a Service platform designed specifically for preclinical drug discovery. This approach aims to accelerate the developmental cycle during the preclinical stage by providing deeper biological understandings of the core mechanisms driving diseases. Leveraging BenchSci's machine learning capabilities, ASCEND retrieves experimental data from both secure internal databases and publicly accessible external repositories, subsequently cross-referencing these findings using datasets categorized by curated ontologies. This process ultimately enables the software to generate evidence-based visualizations mapping the biological pathways associated with different illnesses.

How Is the Preclinical CRO Market Segmented?
The preclinical cromarket covered in this report is segmented -

1) By Service: Bioanalysis And DMPK Studies; Toxicology Testing; Compound Management; Chemistry; Safety Pharmacology; Others Services
2) By Type: Patient Derived Organoid (PDO) Model; Patient Derived Xenograft Model
3) By Animal Model: Small Animal Model; Large Animal Model
4) By Model System: In Vivo; In Vitro
5) By End User: Biopharmaceutical Companies; Government And Academic Institutes; Medical Device Companies; Other End-users

Subsegments:
1) By Bioanalysis And DMPK Studies: Pharmacokinetics Studies; Pharmacodynamics Studies; Drug Metabolism Studies
2) By Toxicology Testing: Acute Toxicity Testing; Chronic Toxicity Testing; Reproductive Toxicity Testing
3) By Compound Management: Sample Management; Inventory Management; Formulation Services
4) By Chemistry: Medicinal Chemistry; Analytical Chemistry; Synthetic Chemistry
5) By Safety Pharmacology: Cardiovascular Safety Studies; Central Nervous System Safety Studies; Respiratory Safety Studies
6) By Other Services: Regulatory Consulting; Project Management; Data Management Services

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Which Companies Are Leading the Charge in Preclinical CRO Market Innovation?
Major companies operating in the preclinical CRO market include Eurofins Scientific SE, PRA Health Sciences Inc., Wuxi AppTec Co. Ltd., Medpace Holdings Inc., Charles River Laboratories International Inc., Laboratory Corporation of America Holdings, SGA SA, Intertek Group plc, Crown Bioscience International, Cynbiose, AmplifyBio LLC, Vivotecnia SL, Simavita Ltd., BioEmission Technology Solutions, Altasciences Company Inc., Global Center For Medical Innovation, Pharmaceutical Product Development LLC, Parexel International Corporation, Envigo RMS Holding Corporation, Veeda Clinical Research Ltd., ICON plc, Kunming Biomed International Ltd., PharmaLegacy Laboratories, NorthEast BioAnalytical Laboratories LLC, MDS Pharma Services, MPI Research, Toxikon Corporation, BioReliance Corporation, Covance Inc., Syngene International Limited

Which Regions Are Leading the Global Preclinical CRO Market in Revenue?
North America was the largest region in the preclinical CRO market in 2024. Asia-Pacific is expected to be the fastest-growing region in the global preclinical CRO market during the forecast period. The regions covered in the preclinical CRO market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa

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