Endogenous Cushing's Syndrome Market Insights Highlight Expanding Outlook Till 2032, DelveInsight Evaluates

DelveInsight's "Endogenous Cushing's Syndrome Market Insights, Epidemiology, and Market Forecast-2032′′ report offers an in-depth understanding of the Endogenous Cushing's Syndrome, historical and forecasted epidemiology as well as the Endogenous Cushing's Syndrome market trends in the United States, EU4 (Germany, Spain, Italy, France) the United Kingdom and Japan.

The latest healthcare forecast report provides an in-depth analysis of Endogenous Cushing's Syndrome, offering comprehensive insights into the Endogenous Cushing's Syndrome revenue trends, prevalence, and treatment landscape. The report delves into key Endogenous Cushing's Syndrome statistics, highlighting the current and projected market size, while examining the efficacy and development of emerging Endogenous Cushing's Syndrome therapies. Additionally, we cover the landscape of Endogenous Cushing's Syndrome clinical trials, providing an overview of ongoing and upcoming studies that are poised to shape the future of Endogenous Cushing's Syndrome treatment. This report is an essential resource for understanding the market dynamics and the evolving therapeutic options within the Endogenous Cushing's Syndrome space.

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Some of the key facts of the Endogenous Cushing's Syndrome Market Report:
• The Endogenous Cushing's Syndrome market size is anticipated to grow with a significant CAGR during the study period (2019-2032)
• In December 2024, Corcept Therapeutics, a US-based biotechnology company, has announced positive long-term results from its Phase III trial evaluating relacorilant as a treatment for individuals with endogenous hypercortisolism (Cushing's syndrome).
• In October 2024, Sparrow Pharmaceuticals, a clinical-stage biopharmaceutical company focused on developing targeted therapies for unmet needs in endocrinology and immunology, announced the completion of its Phase 2 RESCUE trial evaluating clofutriben, a selective HSD-1 inhibitor, for endogenous Cushing's syndrome. All eligible participants who completed the trial opted to continue treatment in an open-label extension (OLE) protocol. Encouraging results from the trial have accelerated plans for the next phase of development, set to begin next year. Additionally, the FDA has granted Orphan Drug Designation to clofutriben for the treatment of endogenous Cushing's syndrome.
• Key Endogenous Cushing's Syndrome Companies: Cortendo AB, RECORDATI GROUP, HRA Pharma, Corcept Therapeutics, and others
• Key Endogenous Cushing's Syndrome Therapies: Levoketconazole, osilodrostat, metyrapone, CORT125134, and others
• The Endogenous Cushing's Syndrome market is expected to surge due to the disease's increasing prevalence and awareness during the forecast period. Furthermore, launching various multiple-stage Endogenous Cushing's Syndrome pipeline products will significantly revolutionize the Endogenous Cushing's Syndrome market dynamics.
• Research by Scaroni et al. (2023) indicates that Cushing syndrome occurs at an incidence rate of 1.5 per 1,000,000 individuals annually and has a prevalence of around 60 per 1,000,000 individuals in Europe. In about 80% of cases, Cushing syndrome is caused by adrenocorticotrophic hormone (ACTH) hypersecretion, resulting in ACTH-dependent Cushing syndrome.
• Cushing's syndrome can be caused by either ACTH-dependent (80% of cases) or ACTH-independent (20% of cases) factors. The latter is primarily attributed to benign adrenal tumors (60%) or malignant tumors (40%). ACTH overproduction can either originate from the pituitary (85% of cases) or result from ectopic tumor secretion (15% of cases). The term "Cushing's disease" is specifically used to refer to ACTH-secreting pituitary tumors.

Endogenous Cushing's Syndrome Overview
Endogenous Cushing's Syndrome is a rare hormonal disorder caused by the body's overproduction of cortisol, a hormone produced by the adrenal glands. This overproduction can result from tumors or abnormalities in the pituitary gland (Cushing's disease), adrenal glands, or other parts of the body that cause excessive cortisol secretion. It contrasts with exogenous Cushing's syndrome, which results from external sources like long-term use of corticosteroid medications.

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Endogenous Cushing's Syndrome Epidemiology
The epidemiology section provides insights into the historical, current, and forecasted epidemiology trends in the seven major countries (7MM) from 2019 to 2032. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. The epidemiology section also provides a detailed analysis of the diagnosed patient pool and future trends.

Endogenous Cushing's Syndrome Epidemiology Segmentation:
The Endogenous Cushing's Syndrome market report proffers epidemiological analysis for the study period 2019-2032 in the 7MM segmented into:
• Total Prevalence of Endogenous Cushing's Syndrome
• Prevalent Cases of Endogenous Cushing's Syndrome by severity
• Gender-specific Prevalence of Endogenous Cushing's Syndrome
• Diagnosed Cases of Episodic and Chronic Endogenous Cushing's Syndrome

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Endogenous Cushing's Syndrome Drugs Uptake and Pipeline Development Activities
The drugs uptake section focuses on the rate of uptake of the potential drugs recently launched in the Endogenous Cushing's Syndrome market or expected to get launched during the study period. The analysis covers Endogenous Cushing's Syndrome market uptake by drugs, patient uptake by therapies, and sales of each drug.
Moreover, the therapeutics assessment section helps understand the drugs with the most rapid uptake and the reasons behind the maximal use of the drugs. Additionally, it compares the drugs based on market share.
The report also covers the Endogenous Cushing's Syndrome Pipeline Development Activities. It provides valuable insights about different therapeutic candidates in various stages and the key companies involved in developing targeted therapeutics. It also analyzes recent developments such as collaborations, acquisitions, mergers, licensing patent details, and other information for emerging therapies.

Endogenous Cushing's Syndrome Therapies and Key Companies
• Levoketconazole: Cortendo AB
• osilodrostat: RECORDATI GROUP
• metyrapone: HRA Pharma
• CORT125134: Corcept Therapeutics

Discover more about therapies set to grab major Endogenous Cushing's Syndrome market share @ Endogenous Cushing's Syndrome Treatment Landscape
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Endogenous Cushing's Syndrome Market Drivers
• Growing Prevalence of Endogenous Cushing's Syndrome
• Advancements in Diagnostic Techniques
• Emerging Targeted Therapies
• Increasing Investment in Rare Disease Research
• Growing Awareness and Early Diagnosis
• Increased Focus on Orphan Drug Development

Endogenous Cushing's Syndrome Market Barriers
• High Treatment Costs
• Limited Treatment Options
• Complexity in Diagnosis
• Side Effects of Current Treatments
• Small Patient Population
• Regulatory Challenges

Scope of the Endogenous Cushing's Syndrome Market Report
• Study Period: 2019-2032
• Coverage: 7MM [The United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan]
• Key Endogenous Cushing's Syndrome Companies: Cortendo AB, RECORDATI GROUP, HRA Pharma, Corcept Therapeutics, and others
• Key Endogenous Cushing's Syndrome Therapies: Levoketconazole, osilodrostat, metyrapone, CORT125134, and others
• Endogenous Cushing's Syndrome Therapeutic Assessment: Endogenous Cushing's Syndrome current marketed and Endogenous Cushing's Syndrome emerging therapies
• Endogenous Cushing's Syndrome Market Dynamics: Endogenous Cushing's Syndrome market drivers and Endogenous Cushing's Syndrome market barriers
• Competitive Intelligence Analysis: SWOT analysis, PESTLE analysis, Porter's five forces, BCG Matrix, Market entry strategies
• Endogenous Cushing's Syndrome Unmet Needs, KOL's views, Analyst's views, Endogenous Cushing's Syndrome Market Access and Reimbursement

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This release was published on openPR.