Nucleic Acid Extraction Equipment Market to Reach USD 1.5 Billion by 2035, Fueled by Demand for Molecular Diagnostics and Genomics Research

The global nucleic acid extraction equipment market (https://www.transparencymarketresearch.com/nucleic-acid-extraction-equipment-market.html) is poised for substantial growth, expanding from US$ 0.8 billion in 2024 to US$ 1.5 billion by 2035, at a steady compound annual growth rate (CAGR) of 6.3% from 2025 to 2035. Market growth is being propelled by increasing genetic and infectious disease prevalence, rapid technological advancements in genomics and next-generation sequencing (NGS), and rising funding in biopharmaceutical and biomedical research.

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Analysts' Viewpoint

The nucleic acid extraction equipment market is undergoing rapid evolution due to the global emphasis on molecular diagnostics, personalized medicine, and precision healthcare. The extraction of DNA and RNA from biological samples forms the backbone of genomic analysis, disease detection, and drug development. As demand for accurate, high-throughput, and automated extraction systems intensifies, manufacturers are focusing on technologies that enhance yield, purity, and speed.

The COVID-19 pandemic significantly accelerated investments in nucleic acid extraction systems as testing volumes surged worldwide. Even post-pandemic, the expansion of infectious disease testing, oncology diagnostics, and genetic screening continues to drive demand for advanced extraction solutions. However, challenges such as high equipment costs and the need for trained laboratory professionals remain key barriers in low- and middle-income economies.

Despite these challenges, the future remains bright for this market, as automated extraction systems and AI-integrated laboratory workflows revolutionize research and diagnostics. Companies focusing on developing compact, high-yield extraction instruments are likely to capture a substantial share of emerging opportunities in this sector.

Market Introduction

Nucleic acid extraction equipment plays a vital role in isolating DNA and RNA from biological materials such as blood, tissues, or cells for use in diagnostics, research, and biotechnology. These systems are essential in clinical diagnostics, forensics, genomics, and proteomics.

Extraction involves cell lysis, purification, and nucleic acid isolation-a process that demands precision and contamination-free handling. Various techniques such as magnetic bead-based, silica membrane-based, and liquid-phase extraction are employed depending on the sample type and downstream applications.

The growing relevance of CRISPR gene editing, NGS, and biomarker discovery has amplified the need for high-quality nucleic acid extraction equipment. Laboratories are increasingly adopting automated systems capable of processing multiple samples simultaneously, thereby minimizing human error and optimizing workflow efficiency.

Market Drivers

Growing Demand for Molecular Diagnostics and Genetic Testing
One of the primary drivers of the nucleic acid extraction equipment market is the surge in molecular diagnostic applications. The ability to detect genetic mutations and pathogens at the molecular level enables early diagnosis and targeted therapies-a key component of precision medicine.

The increased prevalence of infectious diseases, oncological disorders, and hereditary conditions has heightened the demand for reliable genetic testing. Technologies like PCR and NGS require high-quality nucleic acid samples, underscoring the importance of efficient extraction systems.

Furthermore, during the COVID-19 pandemic, global diagnostic labs scaled up extraction capacity to support massive testing operations. This demand surge led to the adoption of automated, high-throughput extraction equipment capable of processing thousands of samples daily. The pandemic thus set a long-term precedent for improved diagnostic preparedness and accelerated automation adoption across laboratories.

Rising Focus on Personalized Medicine and Genomics Research
As the healthcare industry transitions toward personalized and precision medicine, the need to understand individual genetic variations has intensified. Genomic sequencing and biomarker identification depend on the integrity and purity of extracted nucleic acids.

The global boom in genome mapping, pharmacogenomics, and gene therapy has significantly expanded the market scope for nucleic acid extraction systems. Research institutions and pharmaceutical companies are investing heavily in automated solutions that deliver reproducible results.

Collaborations among biotech firms, academic institutions, and clinical laboratories are fueling innovation, enabling next-generation extraction equipment with higher throughput, software integration, and minimal manual intervention. These trends underscore the pivotal role of extraction systems in advancing biomedical research and clinical applications.

Segment Outlook

By Product Type: Automated Systems Lead the Market

Automated extraction systems dominated the market in 2024, accounting for 65.3% of total revenue. These systems streamline workflows by minimizing manual handling, reducing human error, and ensuring consistent sample quality. Their ability to handle large sample volumes with speed and precision makes them indispensable in high-throughput labs and biopharma companies.

Integration of robotics, AI-based process optimization, and data analytics has enhanced the efficiency of automated systems. These innovations contribute to improved yield, purity, and scalability, making automation the preferred choice in both research and clinical diagnostics.

Manual and hybrid systems, while still in use for small-scale or specialized applications, are gradually being replaced by fully automated instruments that align with the broader trend of laboratory digitization and automation.

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Regional Outlook

North America Leads the Global Market

North America accounted for 37.5% of global revenue in 2024, making it the leading region in the nucleic acid extraction equipment market. The U.S. dominates this share due to robust investments in biotechnology R&D, a well-established healthcare infrastructure, and a high concentration of academic and research institutions.

The region's focus on early disease detection, precision diagnostics, and oncology research continues to fuel the demand for advanced extraction solutions. Strong presence of key industry players such as Thermo Fisher Scientific, QIAGEN, and Bio-Rad Laboratories further consolidates the market's leadership in North America.

Meanwhile, Asia Pacific is expected to register the fastest growth over the forecast period, driven by rising investments in genomics research, expanding biopharma manufacturing, and increasing awareness of molecular diagnostics in emerging economies like China, India, and Japan.

Competitive Landscape

The market is moderately consolidated, with major players focusing on strategic collaborations, technological innovation, and product portfolio expansion. Leading companies include:

Thermo Fisher Scientific Inc.
QIAGEN N.V.
Bio-Rad Laboratories, Inc.
Hoffmann-La Roche Ltd.
Agilent Technologies, Inc.
Danaher Corporation
Merck KGaA
Promega Corporation
Tecan Group Ltd.
Zymo Research Corporation

Recent developments highlight strong industry momentum. For instance, in October 2025, Sampled partnered with AutoGen to enhance access to specialized nucleic acid extraction solutions. Similarly, QIAGEN introduced upgraded EZ1 & EZ2 ccfDNA Kits and QIAsymphony DSP Circulating DNA Kits to optimize liquid biopsy workflows, further cementing its market position in automated systems.

The nucleic acid extraction equipment market is on a trajectory of steady growth, supported by expanding applications in genomics, molecular diagnostics, and biopharmaceutical R&D. With a forecasted value of US$ 1.5 billion by 2035, the market's future lies in automation, precision, and integration of AI-driven technologies.

As global healthcare continues to pivot toward genetic-based diagnostics and personalized medicine, the role of efficient nucleic acid extraction systems will be indispensable. Companies that invest in innovation and automation stand to gain a competitive advantage in this evolving, research-intensive landscape.

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