Press release
mRNA Extraction and Purification Market Challenges Include High Cost of Instruments and Reagents Limiting Widespread Adoption
mRNA Extraction and Purification Market
The mRNA Extraction and Purification Market Size is valued at USD 1105.2 Million in 2024 and is predicted to reach USD 7561.2 Million by the year 2034 at a 21.6% CAGR during the forecast period for 2025-2034.
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mRNA extraction and purification are performed using various techniques, including solution-based and column-based methods, with the latter widely preferred due to their superior efficiency and reproducibility. The expansion of the DNA and RNA extraction and purification sector is primarily driven by the increasing focus on genomic research and molecular diagnostics. The growing adoption of personalized medicine, which tailors therapeutic interventions based on individual genetic profiles, has further heightened the demand for precise and reliable nucleic acid isolation methods.
High-quality DNA and RNA samples are essential for researchers and healthcare professionals engaged in molecular studies, including gene expression profiling and transcriptional analysis. Moreover, the isolation and purification of genetic material are critical to the biomedical and pharmaceutical industries, particularly for the development, evaluation, and quality assurance of novel drugs, vaccines, and therapeutic agents. Persistent demand across these applications continues to drive market growth, highlighting the strategic significance of advanced nucleic acid extraction and purification technologies.
List of Significant Players in the MRNA Extraction and Purification Market:
• Agilent Technologies, Inc
• Merck Kgaa
• Qiagen,
• Thermo Fisher Scientific
• Promega Corporation
• Miltenyi Biotec
• Biobasic Inc
• Norgen Biotek
• Zymo Research
• Takara Bio, Inc
• New England Biolabs
• Omega Bio-Tek, Inc
• Hoffmann-La Roche Ag
• Genaxxon Bioscience Gmbh
• Biovision
• Analytik Jena Ag
• Bio-Rad Laboratories, Inc
• AccuBioMed
• NEBNext Poly(A) mRNA Magnetic Isolation Module
• Arraystar, Inc
• Fisher BioReagents
• CD Bioparticles
• United States Biological
• Vdo Biotech
• Bulldog Bio Inc
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Market Dynamics
Drivers:
The global mRNA extraction and purification sector is experiencing robust growth, primarily fueled by the rising prevalence of genetic and chronic diseases. Comprehensive genetic analysis is crucial for diagnosing and managing hereditary conditions such as muscular dystrophy and cystic fibrosis, as well as chronic disorders including cancer, cardiovascular diseases, and obesity.
The accuracy of diagnostics, personalized treatment strategies, and ongoing disease monitoring relies heavily on the availability of high-quality nucleic acids, underscoring the importance of advanced extraction and purification technologies. As the incidence of these conditions increases, demand for reliable and precise tools for isolating intact genetic material continues to expand.
Challenges:
The adoption of sophisticated RNA extraction and purification technologies is constrained by the high costs of specialized equipment and reagents, particularly affecting academic institutions and smaller laboratories with limited financial resources. This economic barrier can hinder competitiveness in the fast-evolving fields of genomics and molecular biology. Additionally, regulatory complexities and the absence of standardized approval frameworks present further obstacles, especially in emerging markets. In regions with underdeveloped regulatory infrastructure, insufficient guidance on biotechnology and healthcare product compliance may restrict market growth despite strong patient demand.
Regional Trends:
North America is expected to maintain a leading position in the mRNA extraction and purification market, supported by significant investments in research and development, advanced technological infrastructure, and strong funding for scientific innovation. Meanwhile, the Asia-Pacific region is demonstrating rapid expansion, driven by enhancements in healthcare infrastructure, increased capital investment from industry stakeholders, growth in pharmaceutical manufacturing capabilities, and the proliferation of regional research initiatives.
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Recent Developments:
• In Oct 2023, Takara Bio Inc. commenced the construction of a new facility, the Center for Cell and Gene Processing III, at its headquarters to manufacture mRNA vaccine components and enzymes for mRNA synthesis. This facility will be built with funding from the Ministry of Economy, Trade and Industry's initiative "Developing Biopharmaceutical Manufacturing Sites to Strengthen Vaccine Production" and their own resources. As a dual-use facility, the Company produces materials for virus vector vaccines and mRNA vaccines, as well as enzymes for mRNA creation, in response to an infectious disease outbreak, following government directives.
Segmentation of mRNA Extraction and Purification Market-
By Product Type-
• Kit and Reagents
• Instruments
By Method Type-
• Polymerase Chain Reaction (PCR)
• Chromatography
o Affinity
OligodT Chromatography Resins
Others
o Ion Exchange
o Hydrophobic Interaction
o Others (Multimodal, Reverse Phase, etc.)
• Oligo Deoxythymidine (dT) Magnetic Particles
• Lithium Chloride Precipitation
By Application-
• Vaccine Production
• Protein Replacement Therapies
• Cancer Immunotherapies
By End-User-
• Hospitals and Clinics
• Biotechnology & Pharmaceutical Companies
• Contract Research Organizations
• Academic & Research Institutions
By Region-
North America-
• The US
• Canada
• Mexico
Europe-
• Germany
• The UK
• France
• Italy
• Spain
• Rest of Europe
Asia-Pacific-
• China
• Japan
• India
• South Korea
• South East Asia
• Rest of Asia Pacific
Latin America-
• Brazil
• Argentina
• Rest of Latin America
Middle East & Africa-
• GCC Countries
• South Africa
• Rest of the Middle East and Africa
Read Overview Report- https://www.insightaceanalytic.com/report/global-mrna-extraction-and-purification-market-/1285
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InsightAce Analytic is a market research and consulting firm that enables clients to make strategic decisions. Our qualitative and quantitative market intelligence solutions inform the need for market and competitive intelligence to expand businesses. We help clients gain competitive advantage by identifying untapped markets, exploring new and competing technologies, segmenting potential markets and repositioning products. Our expertise is in providing syndicated and custom market intelligence reports with an in-depth analysis with key market insights in a timely and cost-effective manner.
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