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Leptomeningeal Metastases Pipeline 2025: Therapies Under Investigation, Clinical Trials Milestones, and FDA Approvals by DelveInsight

11-06-2025 09:04 PM CET | Health & Medicine

Press release from: DelveInsight Business Research

Leptomeningeal Metastases Pipeline 2025: Therapies Under

(Las Vegas, Nevada, United States) As per DelveInsight's assessment, globally, Leptomeningeal Metastases pipeline constitutes 5+ key companies continuously working towards developing 5+ Leptomeningeal Metastases treatment therapies, analysis of Clinical Trials, Therapies, Mechanism of Action, Route of Administration, and Developments analyzes DelveInsight.

"Leptomeningeal Metastases Pipeline Insight, 2025" report by DelveInsight outlines comprehensive insights into the present clinical development scenario and growth prospects across the Leptomeningeal Metastases Market.

The Leptomeningeal Metastases Pipeline report provides a thorough evaluation of both the commercial and clinical aspects of pipeline products, spanning from the pre-clinical development stage to the marketed phase. It includes a comprehensive description of each drug, encompassing its mechanism of action, clinical studies, any approvals through New Drug Applications (NDAs), and various product development activities. These activities involve technological advancements, collaborations, mergers and acquisitions, funding details, designations, and other pertinent information related to the product.

Some of the key takeaways from the Leptomeningeal Metastases Pipeline Report: https://www.delveinsight.com/sample-request/leptomeningeal-metastases-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=gpr
• Companies across the globe are diligently working toward developing novel Leptomeningeal Metastases treatment therapies with a considerable amount of success over the years.
• Leptomeningeal Metastases companies working in the treatment market are NanoLiposome Plus Therapeutics, AstraZeneca, TYK Medicine, Angiochem, and others, are developing therapies for the Leptomeningeal Metastases treatment
• Emerging Leptomeningeal Metastases therapies in the different phases of clinical trials are- Rhenium-186, AZD1390, TY-9591, ANG1005, and others are expected to have a significant impact on the Leptomeningeal Metastases market in the coming years.
• In July 2025, Plus Therapeutics, Inc. (Nasdaq: PSTV), a clinical-stage pharmaceutical company specializing in targeted radiotherapeutics for central nervous system (CNS) cancers, announced that it will present the results of its ReSPECT-LM clinical trial orally and host a sponsored educational symposium at the upcoming SNO/ASCO CNS Metastases Conference.
• In May 2025, Single-dose rhenium (Re186) obisbemeda (Reyobiq; 186RNL) was found to be well tolerated and showed preliminary clinical benefits in patients with leptomeningeal metastases, as reported in the phase 1 dose-escalation ReSPECT-LM trial (NCT05034497).
• In April 2025, Plus Therapeutics, Inc. (Nasdaq: PSTV), a clinical-stage pharmaceutical company focused on developing targeted radiotherapeutics for central nervous system (CNS) cancers using advanced platform technologies, has announced the online release of new data on its lead compound, REYOBIQTM (rhenium Re186 obisbemeda). This data will be featured in an abstract for both an oral presentation and a poster at the Nuclear Medicine and Neurooncology conference.
• In March 2025, The FDA has awarded orphan drug designation to the investigational radiotherapeutic rhenium (186Re) obisbemeda, recognizing its potential as a treatment for leptomeningeal metastases in lung cancer patients. Rhenium (186Re) obisbemeda is designed to deliver high-dose, highly targeted radiation directly to central nervous system (CNS) tumors, aiming to enhance both safety and efficacy by providing a more concentrated and localized radiation dose compared to existing therapies.

Leptomeningeal Metastases Overview
Leptomeningeal Metastases refers to the spread of cancer cells to the leptomeninges, the delicate membranes surrounding the brain and spinal cord. It occurs when malignant cells from primary tumors commonly breast cancer, lung cancer, or melanoma migrate through the bloodstream or cerebrospinal fluid (CSF) and infiltrate the central nervous system. LM can lead to neurological symptoms such as headaches, nausea, vomiting, vision changes, weakness, and cognitive impairment. It is considered a serious and often late-stage complication of cancer, requiring targeted therapies, intrathecal chemotherapy, or radiotherapy to manage symptoms and slow disease progression.

Get a Free Sample PDF Report to know more about Leptomeningeal Metastases Pipeline Therapeutic Assessment-
https://www.delveinsight.com/report-store/leptomeningeal-metastases-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=gpr

Emerging Leptomeningeal Metastases Drugs Under Different Phases of Clinical Development Include:
• AZD1390: AstraZeneca
• TY-9591: TYK Medicine
• Rhenium-186: NanoLiposome Plus Therapeutics
• ANG1005: Angiochem

Leptomeningeal Metastases Pipeline Therapeutics Assessment
• Leptomeningeal Metastases Assessment by Product Type
• Leptomeningeal Metastases By Stage and Product Type
• Leptomeningeal Metastases Assessment by Route of Administration
• Leptomeningeal Metastases By Stage and Route of Administration
• Leptomeningeal Metastases Assessment by Molecule Type
• Leptomeningeal Metastases by Stage and Molecule Type

DelveInsight's Leptomeningeal Metastases Report covers around 5+ products under different phases of clinical development like
• Late-stage products (Phase III)
• Mid-stage products (Phase II)
• Early-stage product (Phase I)
• Pre-clinical and Discovery stage candidates
• Discontinued & Inactive candidates
• Route of Administration

Further Leptomeningeal Metastases product details are provided in the report. Download the Leptomeningeal Metastases pipeline report to learn more about the emerging Leptomeningeal Metastases therapies
https://www.delveinsight.com/sample-request/leptomeningeal-metastases-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=gpr

Some of the key companies in the Leptomeningeal Metastases Therapeutics Market include:
Key companies developing therapies for Leptomeningeal Metastases are - AstraZeneca, Angiochem., Plus Therapeutics, Y-mAbs Therapeutics, and others.

Leptomeningeal Metastases Pipeline Analysis:
The Leptomeningeal Metastases pipeline report provides insights into
• The report provides detailed insights about companies that are developing therapies for the treatment of Leptomeningeal Metastases with aggregate therapies developed by each company for the same.
• It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Leptomeningeal Metastases Treatment.
• Leptomeningeal Metastases key companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
• Leptomeningeal Metastases Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.
• Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the Leptomeningeal Metastases market.
The report is built using data and information traced from the researcher's proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations, and featured press releases from company/university websites and industry-specific third-party sources, etc.

Download Sample PDF Report to know more about Leptomeningeal Metastases drugs and therapies
https://www.delveinsight.com/sample-request/leptomeningeal-metastases-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=gpr

Leptomeningeal Metastases Pipeline Market Drivers
• Increasing Prevalence of Leptomeningeal Metastasess, increase in research and developmental activities are some of the important factors that are fueling the Leptomeningeal Metastases Market.

Leptomeningeal Metastases Pipeline Market Barriers
• However, high-cost associated with the disease, side-effects associated with the treatment and other factors are creating obstacles in the Leptomeningeal Metastases Market growth.

Scope of Leptomeningeal Metastases Pipeline Drug Insight
• Coverage: Global
• Key Leptomeningeal Metastases Companies: NanoLiposome Plus Therapeutics, AstraZeneca, TYK Medicine, Angiochem, and others
• Key Leptomeningeal Metastases Therapies: Rhenium-186, AZD1390, TY-9591, ANG1005, and others
• Leptomeningeal Metastases Therapeutic Assessment: Leptomeningeal Metastases current marketed and Leptomeningeal Metastases emerging therapies
• Leptomeningeal Metastases Market Dynamics: Leptomeningeal Metastases market drivers and Leptomeningeal Metastases market barriers

Request for Sample PDF Report for Leptomeningeal Metastases Pipeline Assessment and clinical trials
https://www.delveinsight.com/sample-request/leptomeningeal-metastases-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=gpr

Contact Us:
Gaurav Bora
gbora@delveinsight.com
+14699457679
Healthcare Consulting
https://www.delveinsight.com/consulting-services

About DelveInsight
DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance. It also offers Healthcare Consulting Services, which benefits in market analysis to accelerate business growth and overcome challenges with a practical approach.

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