Press release
Bronchial Hyperreactivity Market to Reach USD 2.2 Billion by 2034
Bronchial Hyperreactivity
Pune, India, November 2025 - Exactitude Consultancy reports that the Global Bronchial Hyperreactivity (BHR) Market is expected to reach USD 2.2 billion by 2034, growing at a CAGR of 5.7% from 2025 to 2034. The market expansion is driven by the rising global burden of asthma and chronic obstructive pulmonary disease (COPD), improvements in bronchodilator therapies, and growing use of airway reactivity testing in clinical diagnostics.
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Bronchial hyperreactivity, a hallmark of asthma, is characterized by excessive narrowing of airways in response to triggers such as allergens, pollutants, or exercise. Growing emphasis on early detection, biomarker-based treatment, and digital spirometry solutions is enhancing disease management outcomes worldwide.
Key Takeaways
• Market Size: USD 1.25 billion in 2024 → projected USD 2.2 billion by 2034
• CAGR: 5.7% (2025-2034)
• Key Growth Drivers: Rising prevalence of asthma and COPD, precision respiratory medicine, and improved diagnostic accuracy
• Major Players: GlaxoSmithKline (GSK), AstraZeneca, Novartis AG, Boehringer Ingelheim, Teva Pharmaceutical Industries, Cipla Ltd., Sanofi, and Merck & Co.
• Top Regions: North America leads with 38% market share, while Asia-Pacific exhibits fastest CAGR (Less than 6.5%)
Market Story
The bronchial hyperreactivity market is closely linked to advancements in respiratory care and asthma therapeutics. Global asthma cases now exceed 340 million, underscoring the need for precise diagnostic tools and effective long-term management.
Pharmaceutical innovation continues to reshape the therapeutic landscape. AstraZeneca's Tezspire (tezepelumab) and GSK's Trelegy Ellipta are gaining momentum as next-generation biologics and combination inhalers for severe asthma and airway hyperreactivity. Meanwhile, digital spirometry and FeNO testing are becoming standard components of respiratory clinics, enabling earlier and more accurate detection of hyperresponsive airways.
Additionally, the rise of environmental pollution, urbanization, and occupational exposures is amplifying disease incidence in emerging economies, creating new growth opportunities for diagnostics and pharmaceutical firms alike.
Market Segmentation
By Type:
• Intrinsic (Non-Allergic) BHR
• Extrinsic (Allergic) BHR
By Diagnosis Method:
• Spirometry
• Methacholine Challenge Test
• Eucapnic Voluntary Hyperventilation Test
• Exhaled Nitric Oxide (FeNO) Test
By Treatment Type:
• Bronchodilators (β2-Agonists, Anticholinergics)
• Corticosteroids
• Biologics (Monoclonal Antibodies)
• Leukotriene Modifiers
By End User:
• Hospitals
• Pulmonary Clinics
• Research & Academic Institutions
By Region:
• North America
• Europe
• Asia-Pacific
• Latin America
• Middle East & Africa
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Recent Developments
• October 2025: AstraZeneca expanded global access for Tezspire, a biologic for severe asthma, following new approvals across Asia and Latin America.
• August 2025: GSK announced strong clinical results for its triple-therapy inhaler Trelegy Ellipta in reducing bronchial reactivity and asthma exacerbations.
• June 2025: Novartis launched a Phase II trial evaluating QVM149 for hyperreactive airway management in adults.
• April 2025: Boehringer Ingelheim introduced an AI-supported spirometry device for enhanced diagnostic precision in primary care.
Expert Insight
"Bronchial hyperreactivity remains one of the most underdiagnosed respiratory conditions, yet it directly impacts millions of asthma patients," said Dr. Lina Mehta, Senior Respiratory Analyst at Exactitude Consultancy. "Advances in biologics, portable lung diagnostics, and digital inhaler technologies are reshaping how clinicians identify and manage airway hyperresponsiveness."
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Market Drivers
• Rising asthma and COPD prevalence worldwide
• Technological advancements in pulmonary diagnostics and digital spirometry
• Growing demand for biologics and combination inhaler therapies
• Government initiatives to reduce air pollution and improve respiratory healthcare infrastructure
Forecast and Regional Outlook
North America dominates the BHR market due to high healthcare spending, widespread access to advanced respiratory therapies, and ongoing public awareness campaigns. Europe follows closely with strong clinical infrastructure and active research in immunological airway disorders.
Asia-Pacific is projected to grow fastest, supported by large patient populations in India and China, rising air pollution levels, and expanded access to affordable inhalation therapies.
Government and Institutional Initiatives
• U.S. NIH/NHLBI expanded funding under the Severe Asthma Research Program (SARP) to study airway hyperresponsiveness biomarkers.
• European Respiratory Society (ERS) introduced standardized BHR diagnostic guidelines in 2024.
• India's Ministry of Health launched the National Asthma Control Programme to promote early diagnosis and inhaler accessibility.
Conclusion
The Bronchial Hyperreactivity Market is witnessing a pivotal transformation as diagnostics, therapeutics, and digital health converge to improve respiratory care outcomes. With biologics gaining approval, portable testing devices entering clinics, and governments prioritizing lung health initiatives, the next decade promises significant progress in patient management and disease prevention.
This report is also available in the following languages : Japanese (気管支過敏症市場), Korean (기관지 과민반응 시장), Chinese (支气管高反应性市场), French (Marché de l'hyperréactivité bronchique), German (Markt für bronchiale Hyperreaktivität), and Italian (Mercato dell'iperreattività bronchiale), etc.
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