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Japan Therapeutic Plasma Exchange Market Size, Share, and Growth Outlook | Major Players:- Asahi Kasei Corporation., Baxter International Inc., Terumo Corporation | DataM Intelligence Market Research 2025.
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Therapeutic plasma exchange market product launches:-
❇️August 2025: Terumo Corporation introduced a portable plasma exchange device in Japan allowing for outpatient treatment, targeting smaller clinics and remote areas.
❇️April 2025: Asahi Kasei Corporation launched an advanced automated plasma exchange system in Japan with enhanced filtration technology designed for neurological disorder treatments, aiming to improve efficiency and patient outcomes.
Japan Market - Recent M&A Activity 2025
🌐 2025 (current year): Major Japanese therapeutic plasma exchange companies are actively involved in strategic acquisitions aimed at consolidating technological capabilities and expanding product lines, but details and terms of these deals are not as publicly available.
🌐Takeda Pharmaceuticals is increasing investment in plasma-derived therapies which could foreshadow potential future endeavors to merge companies as a means of increasing manufacturing capacity and integrating technology.
🌐In Japan, we are observing a market trend of local companies collaborating with international companies in order to enhance their presence in the market.
Recent Government Approvals:
:- 2025 (current year): The Japanese government is still issuing approvals for novel plasma exchange devices and associated therapies that continue to support advanced health technologies within the healthcare reimbursement system.
:- Japan's regulatory bodies have expedited reviews and approvals for many plasma-derived therapeutic products and devices, allowing patients to access therapies more quickly.
:- Ongoing supportive regulatory frameworks, as well as government healthcare policy efforts, continue to create pathways for innovative and next-generation therapeutic plasma exchange technologies.
Recent FDA and PMDA Approvals in Japan Market (2025):-
-February 2025: FDA and PMDA jointly approved a new plasma exchange automated system developed collaboratively by American and Japanese firms for neurological disorder treatment.
-May 2025: Both agencies cleared new disposable consumables designed to improve safety and reduce procedure times in therapeutic plasma exchange.
-October 2025: Dual regulatory approval was received for a portable plasma exchange device aimed at expanding treatment access outside hospital settings.
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Key Development:
2025 : Japan continues to see tech advances in automated TPE systems and membranes for enhanced process efficiency and patient safety.
Leading companies like Terumo and Asahi Kasei are sponsoring research and creating new next-gen TPE devices, including new features like GUI screens and automatic interfaces.
The growing trend to use TPE as an adjunct to other autoimmune and neurological therapies presents a key area of development.
There is a general effort to expand local manufacturing capacity to meet a growing demand for a stable supply.
🌍Recent Investments Announced 2025
-September 29, 2025: Takeda revised its investment in the plasma-derived therapies manufacturing facility in Osaka, increasing the total investment to 153 billion yen to address rising construction costs and labor challenges, aiming for completion by fiscal year 2029.
-Continuous investments by firms like Terumo and Asahi Kasei support R&D and commercialization of innovative plasma exchange products.
-Government incentives and supportive healthcare policies encourage private sector investment in therapeutic plasma exchange technologies and infrastructure
Key Players with market share in japan market :
-Asahi Kasei Corporation holds approximately 15% market share in the Japan TPE market.
-Baxter International Inc. commands around 20% market share in this market.
-Terumo Corporation owns about 18% market share.
-B. Braun Melsungen AG has roughly 12% market share.
-Fresenius Kabi AG controls approximately 10% market share.
-Haemonetics Corporation's share is around 5%.
-Kawasumi Laboratories holds about 3% market share.
-Adcem Healthcare and Kochin Inlab Equipments India Pvt Ltd together have a small combined share, estimated under 3%.
-Miltenyi Biotec accounts for roughly 2% market share.
Key Segments:
♀️ By Product Type: Includes Apheresis Machines, Filters, and Others, which are essential for separating and purifying plasma components during therapeutic procedures.
♀️ By Indication: Categorized into Neurological, Cardiovascular, Hematology, Renal Disorders, and Others, where plasma exchange helps remove harmful antibodies and toxins to treat chronic and autoimmune conditions.
♀️ By End-User: Includes Hospitals, Ambulatory Surgical Centers, and Others, representing healthcare facilities that utilize plasma exchange for patient treatment, critical care, and advanced therapeutic applications.
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Latest News-
⏭️September 30, 2025: Takeda has provided an update on the expansion of its manufacturing facility for plasma-derived therapies in Juso, Osaka, reaffirming its long-term commitment in spite of challenges such as rising costs and operational and labor shortages.
⏭️Japanese companies are still reporting success in advancing and commercializing new products for plasma exchange.
⏭️The market is benefiting from government health care policies related to aging population and chronic disease management, contributing to increased demand for therapeutic plasma exchange.
FAQ's
Q1: How fast is the Therapeutic plasma exchange market reached growing?
A: The Market is on an impressive growth trajectory, expected to expand at a CAGR of 9.1%.
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