United States Bone Grafts and Substitutes Market 2025: Industry Developments, Future Growth, Share & Industry Insights | Orthofix Medical Inc, DePuy Synthes, Bioventus, Arthrex, Inc

The Bone Grafts and Substitutes Market grew from US$ 3.39 billion to US$ 3.60 billion in 2024 and is projected to reach US$ 6.37 billion by 2033, registering a CAGR of 6.6% during 2025-2033.

DataM Intelligence has published a new research report on "Bone Grafts and Substitutes Market Size 2025". The report explores comprehensive and insightful Information about various key factors like Regional Growth, Segmentation, CAGR, Business Revenue Status of Top Key Players and Drivers. The purpose of this report is to provide a telescopic view of the current market size by value and volume, opportunities, and development status.

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Key Players: Orthofix Medical Inc, DePuy Synthes, Zimmer Biomet, Medtronic, Stryker, Bioventus, Arthrex, Inc

Industry Latest News:

✅ Feb 13, 2025 - LifeNet Health launches OraGen®, the first viable dental bone allograft now available for dental procedures.

✅ Jan 9, 2025 - Medtronic signs an exclusive five-year sales agency agreement to commercialize Kuros' MagnetOs bone graft product.

✅ Apr 23, 2025 - Xtant Medical launches TriviumTM Advanced Bone Graft engineered with PureLocTM Fiber Technology.

✅ Apr 24, 2025 - South Korea's CGBIO receives FDA IDE approval to begin pivotal U.S. trials of NOVOSIS PUTTY (rhBMP-2 containing bone graft substitute).

✅ Jun 2025 (PMA posted) - Cerapedics' PearlMatrixTM Bone Graft receives FDA PMA for lumbar interbody fusion and treated its first U.S. patient after approval.

✅ Sep 17, 2025 - Keensight Capital acquires a majority stake in Isto Biologics (orthobiologics company) a private-equity transaction impacting the orthobiologics/bone grafts space.

✅ Aug 2025 - FDA issues final guidance on animal studies supporting 510(k) submissions for dental bone grafting material devices, clarifying preclinical expectations.

✅ Oct 3, 2025 - Kuros debuts the commercial launch of MagnetOs MIS (minimally invasive sterile, prefilled bone graft delivery system) at SMISS 2025.

✅ Oct 21-22, 2025 - Bone Solutions receives FDA clearances for magnesium-based bone graft substitutes (Mg OSTEOCRETE / Mg OSTEOINJECT) expanding indications including pediatric use.

✅ Feb 1, 2025 - Stryker announces definitive agreement to sell its U.S. spinal implants business (portfolio shifts that affect distribution/competition for bone graft and fusion products).

Growth Forecast Projected:

The Global Bone Grafts and Substitutes Market is anticipated to rise at a considerable rate during the forecast period, between 2025 and 2032. In 2024, the market is growing at a steady rate, and with the rising adoption of strategies by key players, the market is expected to rise over the projected horizon.

Research Process:

Both primary and secondary data sources have been used in the global Bone Grafts and Substitutes Market research report. During the research process, a wide range of industry-affecting factors are examined, including governmental regulations, market conditions, competitive levels, historical data, market situation, technological advancements, upcoming developments, in related businesses, as well as market volatility, prospects, potential barriers, and challenges.

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Key Segments:

By Product Type (Allograft, Bone Graft Substitutes, Others)

By Material (Ceramic based, Polymer-based)

By Application (Spinal Fusion, Dental Bone Grafting, Joint Reconstruction, Craniomaxillofacial, Foot and Ankle, Long Bone, Others)

By End-User (Hospitals, Orthopedic Clinics, Others)

By Region (North America, Europe, South America, Asia Pacific, Middle East, and Africa)

Regional Analysis for Market:

⇥ North America (U.S., Canada, Mexico)

⇥ Europe (U.K., Italy, Germany, Russia, France, Spain, The Netherlands and Rest of Europe)

⇥ Asia-Pacific (India, Japan, China, South Korea, Australia, Indonesia Rest of Asia Pacific)

⇥ South America (Colombia, Brazil, Argentina, Rest of South America)

⇥ Middle East & Africa (Saudi Arabia, U.A.E., South Africa, Rest of Middle East & Africa)

Benefits of the Report:

Chapter 1: Sets the stage by outlining the report's coverage, summarizing key market segments by region, product type, and application. Presents a snapshot of market sizes, growth potential across segments, and anticipated industry evolution both short and long term.

Chapter 2: Highlights pivotal market insights and uncovers the most significant emerging trends driving change within the industry.

Chapter 3: Offers an in-depth look at the competitive landscape among Bone Grafts and Substitutes producers, including revenue shares, strategic moves, and recent mergers and acquisitions.

Chapter 4: Presents comprehensive profiles of the market's key players, delving into details such as revenue, profit margins, product portfolios, and company milestones.

Chapters 5 & 6: Analyze Bone Grafts and Substitutes revenue at both regional and country levels, providing quantitative breakdowns of market sizes, growth opportunities, and development prospects worldwide.

Chapter 7: Focuses on different market segments by type, examining their individual sizes and potential, guiding readers toward high-impact, untapped market areas.

Chapter 8: Explores segmentation by application, evaluating industry growth potential in various downstream markets and pinpointing promising sectors for expansion.

Chapter 9: Provides a thorough review of the industry's supply chain mapping out both upstream and downstream activities.

Chapter 10: Concludes with a summary of the report's key findings and highlights the most critical takeaways for industry stakeholders.

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FAQ's

Q1: What is the current size of the Bone Grafts and Substitutes Market?

A: The Bone Grafts and Substitutes Market stood at US$ 3.39 billion to US$ 3.60 billion in 2024 and is set to experience remarkable growth, reaching US$ 6.37 billion by 2033.

Q2: How fast is the Bone Grafts and Substitutes Market growing?

A: The Market is on an impressive growth trajectory, expected to expand at a CAGR of 6.6% from 2025-2033

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