Essential Tremor Pipeline Drugs Report 2025 highlights MOA, Emerging Therapies, Clinical Trials | DelveInsight

DelveInsight's "Essential Tremor Pipeline Insight 2025" report provides comprehensive insights about 7+ companies and 10+ pipeline drugs in the Essential Tremor pipeline landscape. It covers the Essential Tremor Pipeline drug profiles, including clinical and nonclinical stage products. It also covers the Essential Tremor Pipeline Therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

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Key Takeaways from the Essential Tremor Pipeline Report

* In July 2025, Jazz Pharmaceuticals conducted a study of the safety and efficacy of JZP385 in the treatment of adult participants with moderate to severe ET.
* DelveInsight's Essential Tremor Pipeline report depicts a robust space with 7+ active players working to develop 10+ pipeline therapies for Essential Tremor treatment.
* The leading Essential Tremor Companies such as Merz Pharma, SAGE Therapeutics, GE Healthcare, Praxis Precision Medicines, OB Pharmaceuticals, Novartis, Jazz Pharmaceuticals and others.
* Promising Essential Tremor Therapies such as SAGE-324, CAD-1883, NBI-827104, JZP385, CX-8998, SAGE-217, Memantine, Pregabalin, and others.

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The Essential Tremor Pipeline Report provides disease overview, pipeline scenario and therapeutic assessment of the key pipeline therapies in this domain. The Essential Tremor Pipeline Report also highlights the unmet needs with respect to the Essential Tremor.

Essential Tremor Overview

Essential tremor (ET) is a chronic, progressive neurologic disease. The hallmark motor feature of ET is a 4-12-Hz kinetic tremor (i.e., a tremor that occurs during voluntary movements such as writing or eating) that involves the hands and arms, but which may also eventually spread to involve the head (i.e., neck), voice, jaw, and other body regions. Given the presence of etiologic, clinical, pharmacologic response profile and pathologic heterogeneity, there is increasing support for the notion that ET may be a family of diseases whose central defining feature is kinetic tremor of the arms, and which might more appropriately be referred to as "the essential tremors.

Essential Tremor Emerging Drugs Profile

* SAGE-324: Sage therapeutics

SAGE-324 is an investigational oral neuroactive steroid (NAS) GABAA receptor positive allosteric modulator (PAM). NAS GABAA receptor PAMs bind to both synaptic and extrasynaptic GABAA receptors, enhancing inhibitory activity of the GABAergic system, the major inhibitory neurotransmission system in the brain. GABA is the primary inhibitory neurotransmitter in the central nervous system and plays a critical role in maintaining balanced neuronal activity in the brain. GABA dysregulation has been implicated in the pathophysiology of ET. It is currently being evaluated in Phase II stage of development.

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The Essential Tremor Pipeline report provides insights into:-

* The report provides detailed insights about companies that are developing therapies for the treatment of Essential Tremor with aggregate therapies developed by each company for the same.
* It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Essential Tremor Treatment.
* Essential Tremor Companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
* Essential Tremor Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.
* Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the Essential Tremor market.

Essential Tremor Companies

Merz Pharma, SAGE Therapeutics, GE Healthcare, Praxis Precision Medicines, OB Pharmaceuticals, Novartis, Jazz Pharmaceuticals and others.

Essential Tremor Pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as,

* Intranasal
* Intrathecal
* Intravenous
* Oral
* Oral/Intravenous
* Parenteral
* Subcutaneous
* Subcutaneous/Intramuscular
* Transdermal

Essential Tremor Products have been categorized under various Molecule types such as,

* Antisense oligonucleotide
* Gene therapy
* Hormones
* Neuropeptides
* Oligonucleotides
* Small Molecule
* Triglyceride

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Scope of the Essential Tremor Pipeline Report

* Coverage- Global
* Essential Tremor Companies- Merz Pharma, SAGE Therapeutics, GE Healthcare, Praxis Precision Medicines, OB Pharmaceuticals, Novartis, Jazz Pharmaceuticals and others.
* Essential Tremor Therapies- SAGE-324, CAD-1883, NBI-827104, JZP385, CX-8998, SAGE-217, Memantine, Pregabalin, and others.
* Essential Tremor Therapeutic Assessment by Product Type: Mono, Combination, Mono/Combination
* Essential Tremor Therapeutic Assessment by Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III

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Table of Contents

* Introduction
* Executive Summary
* Essential tremor: Overview
* Pipeline Therapeutics
* Therapeutic Assessment
* Essential tremor- DelveInsight's Analytical Perspective
* Late Stage Products (Phase III)
* Drug name: Company name
* Drug profiles in the detailed report.....
* Mid Stage Products (Phase II)
* PRAX 114: Praxis Precision Medicines
* Drug profiles in the detailed report.....
* Early Stage Products (Phase I/II)
* Drug name: Company name
* Drug profiles in the detailed report.....
* Early Stage Products (Phase I)
* Drug name: Company name
* Drug profiles in the detailed report.....
* Preclinical Stage Products
* TD 567: OB Pharmaceuticals
* Drug profiles in the detailed report.....
* Inactive Products
* Essential tremor Key Companies
* Essential tremor Key Products
* Essential tremor- Unmet Needs
* Essential tremor- Market Drivers and Barriers
* Essential tremor- Future Perspectives and Conclusion
* Essential tremor Analyst Views
* Essential tremor Key Companies
* Appendix

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