United States Diffuse Large B-cell Lymphoma Therapeutics Market Set to Reach USD 7.2 Billion by 2031 | DataM Intelligence

Diffuse Large B-cell Lymphoma Therapeutics Market size was valued at USD 4,107.50 million in 2021 and is estimated to reach at a compound annual growth rate (CAGR) of 7.50% over the forecast period (2024-2031).

Diffuse Large B-cell Lymphoma (DLBCL) therapeutics target one of the most common and aggressive types of non-Hodgkin lymphoma. Standard treatment involves R-CHOP chemotherapy, combining immunotherapy and cytotoxic agents. New approaches include CAR-T cell therapy, monoclonal antibodies, and targeted small molecules. Personalized treatment is guided by molecular subtyping and genetic profiling. Relapsed cases benefit from stem cell transplantation or novel immunotherapies. Research continues to enhance survival rates and minimize treatment-related toxicity.

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☛ Diffuse Large B-cell Lymphoma Therapeutics Market Recent Developments 2025:

United States: Recent Industry Developments

✅ In July 2025, Gilead Sciences announced positive Phase 3 results for CAR-T cell therapy Yescarta in relapsed/refractory DLBCL patients, showing improved overall response and durable remission.

✅ In June 2025, Roche/Genentech expanded the use of Gazyva (obinutuzumab) in combination with chemotherapy for first-line DLBCL treatment, demonstrating enhanced progression-free survival.

✅ In May 2025, Bristol Myers Squibb initiated clinical trials for a bispecific antibody therapy targeting CD20 and CD3, aiming to enhance immune-mediated tumor cell killing in DLBCL.

Japan: Recent Industry Developments

✅ In July 2025, Astellas Pharma advanced novel targeted kinase inhibitors for DLBCL, focusing on patients with high-risk molecular subtypes resistant to standard therapy.

✅ In June 2025, Chugai Pharmaceutical initiated research on ADC (antibody-drug conjugate) therapies for relapsed DLBCL, combining targeted delivery with potent cytotoxic agents.

✅ In May 2025, Takeda Pharmaceutical partnered with Japanese cancer centers to develop personalized immunotherapy protocols using next-generation sequencing for patient stratification in DLBCL treatment.

☛ Diffuse Large B-cell Lymphoma Therapeutics Market Competitive Landscape:

F. Hoffmann-La Roche Ltd, Novartis AG, Celltrion, Karyopharm Therapeutics, Kite Pharma, MorphoSys AG, AbbVie, CTI BioPharma, Seagen Inc., TG Therapeutics.

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☛ Segments Covered in the Diffuse Large B-cell Lymphoma Therapeutics Market:

By Drug Type: Immuno and Targeted Drugs | Others (Combination Drugs)

By Route of Administration: Intravenous Route | Oral

By End User: Hospitals | Cancer Centers | Others

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☛ Regional Analysis for Diffuse Large B-cell Lymphoma Therapeutics Market:

⇥ North America (U.S., Canada, Mexico)

⇥ Europe (U.K., Italy, Germany, Russia, France, Spain, The Netherlands and Rest of Europe)

⇥ Asia-Pacific (India, Japan, China, South Korea, Australia, Indonesia Rest of Asia Pacific)

⇥ South America (Colombia, Brazil, Argentina, Rest of South America)

⇥ Middle East & Africa (Saudi Arabia, U.A.E., South Africa, Rest of Middle East & Africa)

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