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Strategic Forecast for the Normothermic Machine Perfusion Industry: Market Outlook 2025-2034

10-14-2025 08:26 AM CET | Health & Medicine

Press release from: The Business Research Company

Normothermic Machine Perfusion Market

Normothermic Machine Perfusion Market

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Normothermic Machine Perfusion Market Size Growth Forecast: What to Expect by 2025?
The market size of normothermic machine perfusion has experienced swift expansion in the preceding years. The market is projected to expand from $1.28 billion in 2024 to $1.48 billion in 2025, registering a compound annual growth rate (CAGR) of 15.7%. The spike in growth during the historical period can be linked to a surge in organ demand, enhanced preservation results, an increase in donor age and marginal organ use, regulatory backing, escalating investment in medical technologies, and a necessity to minimize cold ischemia time.

How Will the Normothermic Machine Perfusion Market Size Evolve and Grow by 2029?
The market for normothermic machine perfusion is set to experience a swift expansion in the upcoming years. It is anticipated to accelerate to a value of $2.69 billion by 2029, with a compound annual growth rate (CAGR) of 16.1%. The projected growth during the forecast period can be associated with the escalating demand for the utilization of marginal donor organs, increasing success rates of transplants through NMP, ongoing clinical trials and gaining regulatory approvals, investment upsurge in organ preservation technologies, and widespread acceptance in developing economies. Noticeable trends for the forecast period are the integration of AI-based monitoring, the downsizing of perfusion apparatus, synchronization with telemedicine platforms, extension to marginal and DCD (donation after circulatory death) organs, advances in multi-organ perfusion systems, and improved biocompatible materials.

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What Drivers Are Propelling the Growth of Normothermic Machine Perfusion Market Forward?
The surging need for organ transplants is predicted to fuel the expansion of the normothermic machine perfusion market. The process of organ transplantation involves taking a healthy organ from one person to replace a diseased or dysfunctional organ in another. The rise in organ transplantation is linked to the growing instances of terminal organ failure caused by chronic diseases, along with improved surgical methods and immunosuppressive techniques. Normothermic machine perfusion plays a crucial role in organ transplantation as it helps preserve and rejuvenate donated organs by keeping them at body temperature using oxygenated blood or perfusate until the transplant happens. For example, the U.S. Department of Health & Human Services reported in January 2024 that in the previous year, a total of 46,632 organ transplants occurred with both living and deceased donors, which shows an 8.7% increase compared to 2022. Therefore, the burgeoning demand for organ transplants is stimulating the expansion of the normothermic machine perfusion market.

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Which Emerging Trends Are Transforming the Normothermic Machine Perfusion Market in 2025?
Leading firms in the normothermic machine perfusion sector are prioritizing the establishment of sophisticated research centers to quicken innovation, upgrade organ preservation methods, and better transplant results. The enlargement of facilities in the normothermic machine perfusion field enhances organ preservation, research capabilities, and clinical usage, thereby improving transplant outcomes and availability. For example, OrganOx Ltd., a medical equipment production company based in the UK, introduced a new 18,000 square feet global research, development, and production facility in Oxford in May 2024, following the success of its metra device that has positively impacted liver transplant results globally. The establishment of this facility signifies hope for the progression of scientific and clinical innovation via technology for improved treatment of organ failure.

What Are the Key Segments in the Normothermic Machine Perfusion Market?
The normothermic machine perfusion market covered in this report is segmented -

1) By Product Type: Portable Normothermic Machine, Stationary Normothermic Machine
2) By Technology: Mechanical Circulation Technology, Oxygenation Technology, Monitoring Technology
3) By Application: Organ Preservation, Organ Transplantation, Research And Development
4) By End-User: Hospitals And Ambulatory Surgery Centers (ASCs), Specialty Clinics, Other End-Users

Subsegments:
1) By Portable Normothermic Machine: Handheld Portable Devices, Battery-Operated Portable Machines, Transport-Friendly Portable Units
2) By Stationary Normothermic Machine: In-Hospital Stationary Machines, Modular Stationary Systems, Advanced Fixed-Location Units

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Who Are the Key Players Shaping the Normothermic Machine Perfusion Market's Competitive Landscape?
Major companies operating in the normothermic machine perfusion market are CVS Health Corporation, Medtronic plc, Tandem Diabetes Care Inc., Fluent Medical Inc., TransMedics Inc., XENIOS AG, RVL Pharmaceuticals plc, Xvivo Perfusion AB, LifePort Inc., Lifeline Scientific Inc., Organ Recovery Systems Inc., Bridge to Life Ltd., OrganOx Limited, Paragonix Technologies Inc., SurgiCor LLC, Waters Medical Systems LLC, InnovaHealth Partners LP, Prescient Surgical Inc., Vascular Insights LLC, Lung Bioengineering Inc.

What Geographic Markets Are Powering Growth in the Normothermic Machine Perfusion Market?
North America was the largest region in the normothermic machine perfusion market in 2024. The regions covered in the normothermic machine perfusion market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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