Lumbar Degenerative Disc Disease Market Analysis, Size, Share, and Growth Forecast through 2025-2031 -Sorrento Therapeutics, SpineThera, Eliem Therapeutics.

Global Lumbar Degenerative Disc Disease Market reached US$ 12.1 billion in 2022 and is expected to reach US$ 21.3 billion by 2031, growing with a CAGR of 7.4% during the forecast period 2024-2031.

Lumbar Degenerative Disc Disease (DDD) is a condition characterized by the gradual deterioration of the intervertebral discs in the lower back. It commonly results from aging, repetitive strain, or injury. As the discs lose hydration and elasticity, they become less effective at cushioning spinal vertebrae. This can cause chronic back pain, stiffness, and reduced mobility. The condition may also contribute to nerve compression, leading to leg pain or numbness. Treatment options range from physical therapy and medications to surgical interventions in severe cases.

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☛ Lumbar Degenerative Disc Disease Market Recent Developments 2025:

United States: Recent Industry Developments

✅ In July 2025, Medtronic plc launched a new generation of artificial lumbar disc implants designed to mimic natural spinal motion. Clinical trials demonstrated improved patient outcomes and reduced recovery times compared to traditional spinal fusion surgery.

✅ In June 2025, NuVasive, Inc. initiated a multicenter study evaluating its minimally invasive lumbar disc replacement system, which combines advanced imaging with robotic navigation for enhanced surgical precision.

✅ In May 2025, Johnson & Johnson's DePuy Synthes introduced a biologic therapy platform leveraging stem cell-derived growth factors to promote disc regeneration in early-stage degenerative disc disease patients.

Japan: Recent Industry Developments

✅ In July 2025, Kyocera Medical Corporation launched its ceramic-based lumbar disc prosthesis offering superior biocompatibility and wear resistance. The innovation aligns with Japan's growing demand for minimally invasive spine treatments.

✅ In June 2025, Takeda Pharmaceutical announced preclinical progress in its gene therapy candidate aimed at restoring extracellular matrix function in degenerative discs, targeting the root cause of the disease.

✅ In May 2025, Nipro Corporation partnered with Japanese hospitals to develop injectable hydrogel-based disc repair systems, enabling non-surgical treatment for mild to moderate lumbar degeneration.

☛ Lumbar Degenerative Disc Disease Market Competitive Landscape:

Sorrento Therapeutics, SpineThera, Eliem Therapeutics, Scilex Holding, Sinfonia Biotherapeutics, Seikagaku Corporation, Kolon life Science, Vita Sciences, Aurobindo Pharma, and Neurotech.

Research Methodology

We follow a hybrid research approach, combining qualitative insights with rigorous quantitative analysis to deliver reliable and comprehensive market intelligence. Our process begins with extensive secondary research, drawing on trusted industry reports, proprietary databases, and credible market sources. This is then reinforced through targeted primary research, including structured surveys and in-depth interviews with industry leaders, subject matter experts, and key market participants.

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☛ Segments Covered in the Lumbar Degenerative Disc Disease Market:

By Treatment: Type, Drug Treatment, Biologics, Other.

By Route of Administration: Oral, Injectables, Other.

By End-User: Hospitals, Specialty Clinics, Academic Research Centers, Others.

☛ This Report Includes:

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✔ Identification of niche segments and high-growth regions presenting strong opportunities.

✔ Accurate regional forecasts using both top-down and bottom-up approaches.

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☛ Regional Analysis for Lumbar Degenerative Disc Disease Market:

⇥ North America (U.S., Canada, Mexico)

⇥ Europe (U.K., Italy, Germany, Russia, France, Spain, The Netherlands and Rest of Europe)

⇥ Asia-Pacific (India, Japan, China, South Korea, Australia, Indonesia Rest of Asia Pacific)

⇥ South America (Colombia, Brazil, Argentina, Rest of South America)

⇥ Middle East & Africa (Saudi Arabia, U.A.E., South Africa, Rest of Middle East & Africa)

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