Press release
U.S. Genome Editing Market to Reach USD 24.81 Billion by 2034 Driven by CRISPR Breakthroughs
U.S. Genome Editing Market
The U.S. maintains its position as the global leader in genome editing research and commercialization due to a combination of high-caliber scientific infrastructure, progressive regulations, venture capital support, and dominant biotech players. The largest revenue share in 2024 came from biotechnology and pharmaceutical companies, while academic and research institutions are forecast to grow fastest, reflecting a dynamic ecosystem driving both discovery and clinical translation.
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Key Highlights from the Report
➤ CRISPR/Cas9 held 42% share in 2024 and is the fastest-growing genome editing technology.
➤ Biotechnology and pharmaceutical firms drove 52% of market revenues in 2024.
➤ Academic institutions forecasted to grow at 18.9% CAGR, backed by NIH and federal grants.
➤ Ex-vivo delivery methods dominate with 51% share, while in-vivo grows at 19.4% CAGR.
➤ Genetic engineering holds 69% share and leads growth among applications.
➤ Contract research outsourcing is expanding fastest as companies leverage CRO expertise.
Market Segmentation
By end-use, biotechnology and pharmaceutical companies dominate, integrating genome editing into drug discovery, target validation, and therapy pipelines. Academic and government institutes are emerging rapidly due to grant-backed research into gene function and regenerative medicine.
Concerning delivery methods, ex-vivo approaches lead, favored for CAR-T and stem cell therapies where high control over genetic modifications is imperative. In-vivo delivery, using lipid nanoparticles or AAV vectors, is the fastest-growing, enabling treatment for hard-to-reach tissues in rare diseases.
By technology, CRISPR/Cas9 is the most widely adopted for its simplicity and scalability, while prime and base editing are gaining traction for correcting single nucleotide mutations with minimal side effects.
For applications, genetic engineering dominates, driving personalized medicine and advanced cell line engineering. Clinical applications follow closely, powered by genome editing's role in next-generation biopharmaceutical development.
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Regional Insights
Genome editing activity is concentrated in biotech hubs such as Massachusetts, California, and North Carolina, where companies, universities, and venture funds converge. These states lead adoption due to established incubators, top-tier research institutions, and sustained capital investment. Nationwide, strong public-private partnerships speed clinical translation, aided by FDA regulatory frameworks specific to gene editing therapies. Federal projects like the NIH SCGE program ensure coordinated national progress.
Market Dynamics
Market Drivers
Advances in CRISPR and next-gen editing tools, regulatory clarity from the FDA, and strong funding for translational research are fueling the U.S. genome editing market. Public acceptance of gene-based treatments is rising alongside breakthrough clinical trial results.
Market Restraints
Stringent regulatory compliance, the complexity of delivery mechanisms, high R&D costs, and ethical concerns around germline editing may slow rapid adoption, particularly for controversial applications.
Market Opportunities
Expansion into in-vivo treatments for rare diseases, integration with synthetic biology for programmable cells, and the rise of non-viral delivery systems present substantial growth opportunities. Agri-biotech and food sustainability applications also offer untapped potential.
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Reasons to Buy the Report
✔ Comprehensive CAGR and market size forecasts through 2034.
✔ Detailed segmentation by technology, delivery, mode, application, and end-use.
✔ Insight into key players' strategies and emerging technology trends.
✔ Coverage of clinical pipeline developments shaping genome editing adoption.
✔ Evaluation of policy and funding landscapes supporting market expansion.
Frequently Asked Questions (FAQs)
◆ How big is the U.S. genome editing market in 2024 and what is its forecast for 2034?
◆ Who are the key players driving innovation in genome editing technologies?
◆ What is the projected growth rate of CRISPR/Cas9 applications in the U.S.?
◆ Which delivery method dominates the U.S. genome editing market currently?
◆ Which states are leading the adoption of genome editing technologies?
Company Insights
Merck KGaA
Cibus
Recombinetics, Inc.
Sangamo
Editas Medicine
Precision Biosciences
CRISPR Therapeutics
Intellia Therapeutics, Inc.
Caribou Biosciences, Inc.
Cellectis S.A.
GenScript
AstraZeneca
Integrated DNA Technologies, Inc.
Egenesis Inc.
New England Biolabs
OriGene Technologies, Inc.
Lonza
Thermo Fisher Scientific, Inc.
Recent Developments:
March 2025: Editas Medicine announced leadership changes to accelerate clinical programs, notably EDIT-301 for sickle cell disease.
February 2025: Intellia Therapeutics received FDA fast-track designation for in-vivo CRISPR therapy targeting hereditary angioedema, showing promising Phase II interim data.
Conclusion
With a projected CAGR of 16.8%, the U.S. genome editing market is transitioning from groundbreaking research to mainstream clinical and commercial applications. CRISPR/Cas9 remains the gold standard, but innovations in base and prime editing are expanding therapeutic capabilities while minimizing risk. Federal backing, strong biotech ecosystems, and rapid advancements in delivery methods position the U.S. to remain the world leader in genome editing, shaping the future of medicine, agriculture, and synthetic biology over the coming decade.
Contact Us
Mr. Sai Kiran
DataM Intelligence 4market Research LLP Ground floor
DSL Abacus IT Park, Industrial Development Area
Uppal, Hyderabad, Telangana 500039
USA: +1 877-441-4866
Email: Sai.k@datamintelligence.com
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About Us
DataM Intelligence 4Market Research is a comprehensive market intelligence platform offering syndicated and customized reports along with expert consulting across multiple industries, including chemicals, healthcare, agriculture, food & beverages, and more. With extensive experience and a strategy-focused approach, DataM provides businesses and individuals with reliable market insights, statistical forecasts, and personalized research solutions to help them make informed decisions and successfully bring innovations to market.
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