Shigella Vaccines Pipeline Market: Clinical Trial Analysis, Trends, and Forecast 2024-2031

The Shigella Vaccines Pipeline Market to grow at a HIGH CAGR during the forecast period 2024- 2031.

The Shigella Vaccines Pipeline Market focuses on vaccines under development to prevent Shigella bacterial infections causing dysentery. Pipeline candidates include live attenuated, conjugate, and subunit vaccines. Market growth is driven by the global need for vaccines in regions with poor sanitation and high disease prevalence. Clinical trials and research collaborations accelerate candidate evaluation. Regulatory support for infectious disease vaccines encourages development. The market outlook is promising with increasing investment in preventive healthcare and global immunization programs.

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☛ Shigella Vaccines Pipeline Market Recent Developments 2025:

✅ In June 2025, GSK licensed its Shigella vaccine candidate altSonflex1-2-3 to Bharat Biotech International (BBIL). The vaccine uses GMMA (Generalized Modules for Membrane Antigens) technology and targets multiple Shigella serotypes including S. sonnei and S. flexneri types 1b, 2a, and 3a. Bharat Biotech will lead Phase 3 trials, regulatory submissions, and large-scale manufacturing.

✅ In April 2025, Valneva SE and LimmaTech Biologics AG began a Phase 2 infant safety and immunogenicity study of their tetravalent bioconjugate vaccine candidate S4V2 (Shigella4V2). The trial is evaluating two dose levels in nine-month-old infants in Kenya, with results expected in late 2025.

✅ In November 2024, Valneva/LimmaTech initiated a Phase 2b Controlled Human Infection Model (CHIM) study of S4V2 in healthy adults aged 18-50 in the United States. This study aims to assess preliminary efficacy and immune protection under controlled exposure conditions.

✅ In October 2024, S4V2 received FDA Fast Track designation, expediting its development and review process given the high unmet need for Shigella prevention globally.

☛ Shigella Vaccines Pipeline Market Competitive Landscape:

LimmaTech Biologics AG, Eveliqure Biotechnologies GmbH, Zhi Fei Biological, Vaxcyte, Inventprise.

Research Methodology

We follow a hybrid research approach, combining qualitative insights with rigorous quantitative analysis to deliver reliable and comprehensive market intelligence. Our process begins with extensive secondary research, drawing on trusted industry reports, proprietary databases, and credible market sources. This is then reinforced through targeted primary research, including structured surveys and in-depth interviews with industry leaders, subject matter experts, and key market participants.

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☛ Segments Covered in the Shigella Vaccines Pipeline Market:

By Vaccine Type: Live Attenuated Vaccines, Inactivated Vaccines, Whole-cell inactivated vaccines, Subunit inactivated vaccines, Conjugate Vaccines, Others.

By Age Group: Infants, Childrens.

By End User: Hospitals, Clinics, Non-Governmental Organizations (NGOs), Vaccination Centers, Others.

☛ This Report Includes:

✔ Comprehensive go-to-market strategies with actionable insights.

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✔ Identification of niche segments and high-growth regions presenting strong opportunities.

✔ Accurate regional forecasts using both top-down and bottom-up approaches.

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☛ Regional Analysis for Shigella Vaccines Pipeline Market:

⇥ North America (U.S., Canada, Mexico)

⇥ Europe (U.K., Italy, Germany, Russia, France, Spain, The Netherlands and Rest of Europe)

⇥ Asia-Pacific (India, Japan, China, South Korea, Australia, Indonesia Rest of Asia Pacific)

⇥ South America (Colombia, Brazil, Argentina, Rest of South America)

⇥ Middle East & Africa (Saudi Arabia, U.A.E., South Africa, Rest of Middle East & Africa)

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