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Cancer Immunotherapy Market Size to Reach US$ 261.74 Billion by 2033 at 7.9% CAGR

10-07-2025 01:21 PM CET | Health & Medicine

Press release from: DataM Intelligence 4Market Research LLP

Cancer Immunotherapy Market

Cancer Immunotherapy Market

The global cancer immunotherapy market was valued at US$ 137.70 billion in 2024 and is projected to reach US$ 261.74 billion by 2033, expanding at a CAGR of 7.9% during the forecast period (2025-2033), according to DataM Intelligence. The steady rise in global cancer incidence, increased research investments, and expanding clinical approvals for novel immunotherapies are fueling significant market advancements.

Cancer immunotherapy, also known as immuno-oncology, enhances the body's natural immune response to identify and destroy cancer cells. With leading treatments such as immune checkpoint inhibitors, CAR-T cell therapies, monoclonal antibodies, and cancer vaccines, this therapeutic class has revolutionized cancer management and patient survival outcomes.

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Key Highlights from the Report

➤ Global market size to reach US$ 261.74 billion by 2033 with a 7.9% CAGR
➤ Immune checkpoint inhibitors hold the largest market share at 37.5% (2024)
➤ North America leads the market with 57.4% share owing to strong R&D and drug sales
➤ Keytruda (Pembrolizumab) tops global sales, contributing nearly US$ 29.82 billion in 2024
➤ Surge in cancer incidence projected to surpass 29.9 million global cases by 2040 (GLOBOCAN)
➤ Increasing regulatory approvals for new immunotherapies strengthen global market momentum

Market Segmentation

The cancer immunotherapy market is segmented by type, indication, and region.

By type, immune checkpoint inhibitors lead the global market, accounting for 37.5% share in 2024. These drugs block proteins like PD-1, PD-L1, and CTLA-4, preventing cancer cells from evading immune detection. Flagship products such as Keytruda (Merck & Co.), Opdivo (Bristol-Myers Squibb), and Tecentriq (Roche) continue to dominate due to wide-ranging indications and strong clinical outcomes.

Checkpoint inhibitors have redefined cancer therapy, offering long-term remission and higher survival rates across multiple tumor types, including lung, melanoma, breast, and urinary cancers. Ongoing research continues to expand their use for emerging indications and combination therapies.

Regional Insights

North America Dominates the Global Cancer Immunotherapy Market

North America leads with a 57.4% market share in 2024, supported by robust healthcare infrastructure, rapid adoption of innovative treatments, and a high cancer burden. In the U.S., immunotherapy sales generated record revenues, with Keytruda contributing over 60% of its total sales regionally.

The region's strong oncology pipeline and routine integration of immunotherapies into treatment guidelines have further solidified its dominance. Programs by FDA and clinical research consortia have accelerated access to breakthrough therapies for patients across multiple cancer categories.

Asia-Pacific: Fastest Growing Region

The Asia-Pacific region is set to witness the fastest growth rate, owing to rising cancer prevalence, improving healthcare infrastructure, and expanding domestic drug manufacturing capabilities. Increasing government approvals - such as China's NMPA approval of Akeso's Ivonescimab (PD-1/VEGF bispecific antibody) in April 2025 - are improving availability of advanced immunotherapies locally.

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Market Dynamics

Market Drivers

The increasing global incidence of cancer and a strong shift toward targeted therapies are major drivers of market growth. Rising R&D investment and expansion of immunotherapy indications enable early intervention and personalized cancer care.

Market Restraints

High cost remains a critical barrier to widespread adoption. For instance, Merck's Keytruda treatment costs approximately US$ 23,590 per six-week dose, limiting accessibility in low- and middle-income countries despite its proven efficacy.

Market Opportunities

Expanding clinical research, approvals in emerging markets, and combination immunotherapies leveraging AI and biomarker profiling represent strong growth opportunities. Biotech collaborations and adaptive trial designs are expected to accelerate innovation through the forecast period.

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Reasons to Buy the Report

✔ Comprehensive insights into global cancer immunotherapy pipeline trends and growth drivers
✔ Detailed market segmentation by treatment class, indication, and geography
✔ Evaluation of regulatory landscapes shaping access to advanced therapies
✔ Competitive analysis highlighting key players and novel drug approvals
✔ Future market opportunities in emerging economies and next-generation CAR-T therapies

Frequently Asked Questions (FAQs)

◆ How big is the global cancer immunotherapy market in 2024?
◆ Who are the leading companies driving innovation in immuno-oncology?
◆ What are the top-selling immune checkpoint inhibitors globally?
◆ What is the expected CAGR of the market from 2025-2033?
◆ Which region dominates the global cancer immunotherapy industry?

Company Insights

Merck & Co., Inc.

Bristol-Myers Squibb Company

F. Hoffmann-La Roche Ltd

AstraZeneca

Pfizer Inc.

Johnson & Johnson Services, Inc.

Novartis AG

Kite Pharma, Inc.

Dendreon Pharmaceuticals LLC

Amgen Inc.

Recent Developments:

April 2025 - Akeso, Inc. received NMPA approval in China for Ivonescimab, the world's first PD-1/VEGF bispecific antibody therapy for PD-L1-positive NSCLC patients.

September 2024 - F. Hoffmann-La Roche Ltd gained U.S. FDA approval for Tecentriq Hybreza, the first subcutaneous PD-L1 inhibitor approved in the United States.

September 2024 - Merck (MSD) obtained regulatory clearance in Japan for Keytruda to treat advanced non-small cell lung carcinoma and urothelial carcinoma.

Conclusion

The cancer immunotherapy market is poised for continued transformation as science and technology converge to advance precision medicine. Growing cancer prevalence worldwide, combined with breakthrough progress in immune checkpoint inhibitors and bispecific antibody development, is reinforcing the market's global footprint. With North America maintaining leadership and Asia-Pacific emerging as a key growth region, the next decade will mark a pivotal era in immuno-oncology, redefining cancer treatment standards and survival outcomes worldwide.

Contact Us

Mr. Sai Kiran
DataM Intelligence 4market Research LLP Ground floor
DSL Abacus IT Park, Industrial Development Area
Uppal, Hyderabad, Telangana 500039
USA: +1 877-441-4866
Email: Sai.k@datamintelligence.com
Visit Our Website: https://www.datamintelligence.com

About Us

DataM Intelligence 4Market Research is a comprehensive market intelligence platform offering syndicated and customized reports along with expert consulting across multiple industries, including chemicals, healthcare, agriculture, food & beverages, and more. With extensive experience and a strategy-focused approach, DataM provides businesses and individuals with reliable market insights, statistical forecasts, and personalized research solutions to help them make informed decisions and successfully bring innovations to market.

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