United States Chronic Lower Back Pain Drugs Market is expected to reach US$ 4,608.47 Million by 2033 | Top key players - Johnson & Johnson, GSK plc, Bayer AG.

Market Size and Forecast:

The Chronic Lower Back Pain Drugs Market size reached US$ 2,768.82 million in 2024 and is expected to reach US$ 4,608.47 million by 2033, growing at a CAGR of 6.4% during the forecast period of 2025-2033.

The Chronic Lower Back Pain Drugs Market report, published by DataM Intelligence, provides in-depth insights and analysis on key market trends, growth opportunities, and emerging challenges. Committed to delivering actionable intelligence, DataM Intelligence empowers businesses to make informed decisions and stay ahead of the competition. Through a combination of qualitative and quantitative research methods, it offers comprehensive reports that help clients navigate complex market landscapes, drive strategic growth, and seize new opportunities in an ever-evolving global market.

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The Chronic Lower Back Pain Drugs Market encompasses the development, production, and commercialization of medications aimed at alleviating persistent lower back pain. It includes analgesics, anti-inflammatory drugs, muscle relaxants, and neuropathic pain treatments. The market is driven by rising prevalence of chronic back conditions, aging populations, lifestyle factors, and growing demand for effective, safe, and long-term pain management solutions.

Recent Key Developments of United States and Japan:

USA:
FDA Approval for Fibromyalgia Drug: The FDA approved TNX-102 SL (Tonmya) on August 15, 2025, for the treatment of fibromyalgia, which often co-exists with or mimics chronic lower back pain. It is a new class of non-opioid analgesics.

Trial Analysis for Lumbosacral Radicular Pain: A post-hoc analysis of the C.L.E.A.R. trial for SP-102 (SEMDEXA), targeting lumbosacral radicular pain (often a component of CLBP), was presented in May 2025, suggesting movement toward clinical meaningfulness, with future developments anticipated in the forecast period.

Japan:
Decreasing Opioid and NSAID Use: Continuing a trend, the proportion of patients receiving non-surgical interventions (like nerve blocks) who use Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) and opioids significantly decreased.

Increasing Use of Alternative Drugs: There was a significant increase in the proportion of patients using acetaminophen, antiseizure medications, and certain antidepressants (SNRIs and TCAs) for low back pain management in the context of interventional treatments.

List of the Key Players in the Chronic Lower Back Pain Drugs Market:

Johnson & Johnson
GSK plc
Bayer AG
Aurobindo Pharma USA
Viatris Inc.
Mankind Pharma
Sanofi S.A.
Eli Lilly and Company
Dr. Reddy's Laboratories Ltd.
Sun Pharmaceutical Industries Ltd.

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This Report Covers:

✔ Go-to-market Strategy.

✔ Neutral perspective on the market performance.

✔Development trends, competitive landscape analysis, supply side analysis, demand side analysis, year-on-year growth, competitive benchmarking, vendor identification, and other significant analysis, as well as development status.

✔Customized regional/country reports as per request and country level analysis.

✔ Potential & niche segments and regions exhibiting promising growth covered.

✔ Analysis of Market Size (historical and forecast), Total Addressable Market (TAM), Serviceable Available Market (SAM), Serviceable Obtainable Market (SOM), Market Growth, Technological Trends, Market Share, Market Dynamics, Competitive Landscape and Major Players (Innovators, Start-ups, Laggard, and Pioneer).

Segments Covered in the Chronic Lower Back Pain Drugs Market:

By Drug Class: Nonsteroidal Anti-Inflammatory Drugs (NSAIDs), Analgesics, Antidepressants, Opioids, Others.

By Route of Administration: Oral, Parenteral.

By Distribution Channel: Hospital Pharmacies, Retail Pharmacies, Online Pharmacies.

Regional Analysis:

⇥ North America (U.S., Canada, Mexico)

⇥ Europe (U.K., Italy, Germany, Russia, France, Spain, The Netherlands and Rest of Europe)

⇥ Asia-Pacific (India, Japan, China, South Korea, Australia, Indonesia Rest of Asia Pacific)

⇥ South America (Colombia, Brazil, Argentina, Rest of South America)

⇥ Middle East & Africa (Saudi Arabia, U.A.E., South Africa, Rest of Middle East & Africa)

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Chapter Outline

⏩ Market Overview: It contains five chapters, as well as information about the research scope, major manufacturers covered, market segments, Chronic Lower Back Pain Drugs market segments, study objectives, and years considered.

⏩ Market Landscape: The competition in the Global Chronic Lower Back Pain Drugs Market is evaluated here in terms of value, turnover, revenues, and market share by organization, as well as market rate, competitive landscape, and recent developments, transaction, growth, sale, and market shares of top companies.

⏩ Companies Profiles: The Global Chronic Lower Back Pain Drugs market's leading players are studied based on sales, main products, gross profit margin, revenue, price, and growth production.

⏩ Market Outlook by Region: The report goes through gross margin, sales, income, supply, market share, CAGR, and market size by region in this segment. North America, Europe, Asia Pacific, Middle East & Africa, and South America are among the regions and countries studied in depth in this study.

⏩ Market Segments: It contains the deep research study which interprets how different end-user/application/type segments contribute to the Chronic Lower Back Pain Drugs Market.

⏩ Market Forecast: Production Side: In this part of the report, the authors have focused on production and production value forecast, key producers forecast, and production and production value forecast by type.

⏩ Research Findings: This section of the report showcases the findings and analysis of the report.

⏩ Conclusion: This portion of the report is the last section of the report where the conclusion of the research study is provided.

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