What You Need to Know About Unexplained Infertility

You may be diagnosed with unexplained infertility if standard tests don't show any reason why you're unable to conceive naturally. Some cases resolve without intervention, but others require a comprehensive evaluation to identify previously missed conditions. Understanding the diagnosis and condition enables you to make informed decisions for your next steps. Here are a few things you should know about infertility that's unexplained by standard tests:

Associated Hidden Conditions

Although an unexplained diagnosis doesn't name any specific underlying cause of infertility, the condition has various medical reasons. The obvious one is endometriosis, a condition where endometrial cells and tissues grow outside the uterus. Normal endometrial tissues grow during ovulation in anticipation of fertilization and implantation. When that doesn't happen, they shed during menses.

Sometimes these cells grow around the ovaries, inside the fallopian tubes, or in the pelvic cavity. Abnormal growths may block pathways for the sperm and egg to meet or cause inflammation of the uterine wall. Endometriosis may cause pain and other symptoms, but some cases are silent and remain a leading cause of unexplained infertility (https://receptivadx.com). Couples may not find out because standard tests don't check for signs of endometriosis. Silent cases also don't have any diagnosable symptoms except the infertility.

Other conditions associated with this type of infertility include endometritis, a chronic bacterial infection, progesterone resistance, and subtle egg or sperm defects. These conditions can disrupt conception without showing up in routine tests. Learning about the possible causes of infertility allows doctors to perform targeted evaluations for those specific markers.

Comprehensive Fertility Testing

Fertility doctors offer routine tests that check your hormone levels, ovulation patterns, and the overall condition of your fallopian tubes. If these standard tests return normal, doctors may recommend advanced imaging, such as ultrasounds, or take biopsies to check for chronic infections. Further evaluation extends to undetectable factors, such as sperm function, timing of fertilization, and egg quality issues. This process rules out common causes of fertility and leads to the diagnosis of your condition being unexplained if the tests yield no results.

After exhausting standard tests, fertility doctors may recommend non-traditional assessments, such as BCL6 and CD138. A BCL6 test checks for markers of the unique protein associated with an inflamed uterine wall. If the results are positive, seek further evaluation for endometriosis, which is linked to elevated levels of the BCL6 gene even in silent cases. Tests can include biopsies and imaging to confirm the presence of abnormal endometrial growths.

A CD38 test checks for plasma activity, which signifies potential chronic infections, such as endometritis. Chronic bacterial infections affect the uterine condition, receptivity, and implantation. Fertility doctors also check for progesterone resistance, which affects how the uterine wall responds to elevated progesterone levels during ovulation and implantation.

Holistic Treatment Options

Fertility doctors offer various treatment options for couples looking to start a family. If standard tests don't reveal an issue, you may still try pregnancy medication and lifestyle adjustments to optimize your overall health. For issues like endometriosis, doctors use a combination of medication, monitoring, and surgery. Medication includes hormones or birth control options that suppress your menstrual cycle. Monitoring checks whether intervention is necessary, especially in early-stage endometriosis. Surgery involves laparoscopic removal, where the abnormal growths are surgically removed if they block the fallopian tubes and other pathways. Bacterial infections, such as endometritis, are treated using carefully selected antibiotics. Doctors may take a biopsy to identify the specific bacteria, allowing them to create targeted antibiotics. For conditions like progesterone resistance, treatment could involve medication to increase the level of the hormone or enhance the receptivity of the uterine wall.

Doctors also offer assisted reproductive technologies like IVF, IUI, and donor eggs and sperm. These options bypass natural conception but require optimal health and checks for endometriosis and other causes of IVF failure. Other treatment options include genetic testing to identify potential chromosomal anomalies and gene-related disorders that affect implantation and embryo development. Holistic treatment covers targeted interventions and general practices that enhance your chances of natural or assisted reproduction.

Learn Your Next Action After Unexplained Infertility

Even if your infertility can't be explained by routine tests, doctors may still find ways around the issue. Tests for endometriosis, endometritis, and progesterone resistance offer a starting point. Personalized treatment through medication and health optimization also boosts your chances of conceiving. Get a test today to start exploring your next action following an unexplained infertility diagnosis.

Site: https://receptivadx.com

This release was published on openPR.